A5008611402- Anesthesia and Neurotoxicity Research
- Knee injuries and reconstruction techniques
- Salivary Gland Tumors Diagnosis and Treatment
- Cancer Cells and Metastasis
- Ear and Head Tumors
- Urinary and Genital Oncology Studies
- Coenzyme Q10 studies and effects
- Skin Protection and Aging
- interferon and immune responses
- Cancer, Hypoxia, and Metabolism
- Head and Neck Cancer Studies
- Neuroscience and Neuropharmacology Research
- Inflammasome and immune disorders
- Heme Oxygenase-1 and Carbon Monoxide
- Bladder and Urothelial Cancer Treatments
- Mitochondrial Function and Pathology
- Cellular Mechanics and Interactions
- Glutathione Transferases and Polymorphisms
- Cleft Lip and Palate Research
- Traditional Chinese Medicine Analysis
- Genomics, phytochemicals, and oxidative stress
- Hippo pathway signaling and YAP/TAZ
- Endoplasmic Reticulum Stress and Disease
- Cytokine Signaling Pathways and Interactions
- Total Knee Arthroplasty Outcomes
Shandong First Medical University
1997-2024
Changchun University of Chinese Medicine
2023-2024
Huazhong University of Science and Technology
2009-2021
Tongji Hospital
1999-2015
Abstract Renal fibrosis, particularly tubulointerstitial fibrosis is considered to be the final manifestation of almost all chronic kidney diseases (CKDs). Herein we demonstrated evidence that CHOP-related ER stress associated with development renal in both CKD patients and unilateral ureteral obstruction (UUO)-induced animals, specifically, mice deficient Chop were protected from UUO-induced fibrosis. Mechanistic studies revealed loss tubular cells apoptosis secondary necrosis along...
Abstract Despite decades of significant progress in understanding the molecular mechanisms malignant tumorigenic cells, it remains elusive what these cells are and controls growth cells. Recently, we have mechanically selected grown highly tumor-repopulating (TRCs), a small sub-population cancer by culturing single soft fibrin matrices. However, is unclear regulates TRC besides Sox2. Here show that nuclear protein 1 (Nupr1), independent Sox2, downregulated TRCs melanoma, ovarian breast...
<title>Abstract</title> <bold>Purpose</bold>: This study investigates the relationship between ankle pain and lower extremity imaging parameters in patients following total knee arthroplasty (TKA). <bold>Methods</bold>: From September 2023 to February 2024, 41 with osteoarthritis (KOA) who underwent primary TKA were included this study. The incidence of was assessed six months post-surgery, limb measured analyze their pain. <bold>Results</bold>: Among patients, 13 experienced after TKA,...
To explore the effect of melatonin (MT) on 2, 2', 4, 4'-tetrabromodiphenylether (PBDE-47)-induced abnormal autophagy and apoptosis in rat adrenal medullary pheochromocytoma PC12 cells.PC12 cells were pretreated with a concentration gradient (12.5, 25, 50, 100, 200 μmol/L) for 2 h before exposure to 20 μmol/L PBDE-47 24 determine optimal cell treatment. In subsequent experiments, treated 0.5‰ DMSO (control group), PBDE-47, 25 melatonin, or both melatonin. Immunofluorescence assay was used...