Rafik Ait-Sarkouh
A5098733380- Fibroblast Growth Factor Research
- Medical Imaging and Pathology Studies
- Sarcoma Diagnosis and Treatment
- Metastasis and carcinoma case studies
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
Debiopharm (Switzerland)
2024
This multicenter phase II basket trial investigated the efficacy, safety, and pharmacokinetics of Debio 1347, an investigational, oral, highly selective, ATP-competitive, small molecule inhibitor FGFR1-3, in patients with solid tumors harboring a functional FGFR1-3 fusion.
<p>Supplementary Figure S2. Progression-free survival.</p>
<p>Supplementary methods</p>
<p>Supplementary Figure S1. Study CONSORT diagram.</p>
<div>AbstractPurpose:<p>This multicenter phase II basket trial investigated the efficacy, safety, and pharmacokinetics of Debio 1347, an investigational, oral, highly selective, ATP-competitive, small molecule inhibitor FGFR1–3, in patients with solid tumors harboring a functional <i>FGFR1–3</i> fusion.</p>Patients Methods:<p>Eligible adults had previously treated locally advanced (unresectable) or metastatic biliary tract (cohort 1), urothelial 2),...