A5045379423- Parkinson's Disease Mechanisms and Treatments
- Neurological disorders and treatments
- Body Image and Dysmorphia Studies
- Reproductive tract infections research
- Acute Ischemic Stroke Management
- Neurological Complications and Syndromes
- Autism Spectrum Disorder Research
- Hemoglobinopathies and Related Disorders
- Voice and Speech Disorders
- Dysphagia Assessment and Management
- Neurogenetic and Muscular Disorders Research
- Syphilis Diagnosis and Treatment
New York State Department of Health
2024
University of Wisconsin–Madison
2017-2020
Neuromuscular pathology is found in the larynx and pharynx humans with Parkinson disease (PD); however, it unknown when this emerges. We hypothesized that occurs early (premanifest) stages. To address this, we used Pink1−/− rat model of PD, which shows age-dependent dopaminergic neuron loss, locomotor deficits, deficits related to laryngeal function. report findings thyroarytenoid muscle (TA) rats compared wild-type (WT) control at 4 6 mo age. TAs were analyzed for force production, myosin...
Parkinson disease (PD) is associated with speech and swallowing difficulties likely due to pathology in widespread brain nervous system regions. In post-mortem studies of PD, has been reported pharyngeal laryngeal nerves muscles. However, it unknown whether PD neuromuscular changes the tongue. Prior work a rat model (Pink1-/-) showed oromotor deficits premanifest stage which suggested sensorimotor impairments these functions. The present study tested hypothesis that Pink1-/- rats show...
Bacterial sexually transmitted infections (STIs) continue to increase in the United States. Despite evidence of effectiveness doxycycline post-exposure prophylaxis (Doxy-PEP) prevent STIs, little is known about providers' attitudes and willingness implement Doxy-PEP.
Groncy, P.; Softley, T.*; Bradley, W.*; Lake, J.*; Cooney, M.*; Saneda, D.* Author Information