A5101540455- Reproductive biology and impacts on aquatic species
- Child and Adolescent Health
- Aquaculture Nutrition and Growth
- Microbial Natural Products and Biosynthesis
- Endodontics and Root Canal Treatments
- Cooperative Studies and Economics
- Child and Adolescent Psychosocial and Emotional Development
- Esophageal and GI Pathology
- Youth Substance Use and School Attendance
- Heart Failure Treatment and Management
- Dental Research and COVID-19
- Eosinophilic Esophagitis
- Early Childhood Education and Development
- Gastrointestinal Tumor Research and Treatment
- Enzyme Structure and Function
- Ethics and Legal Issues in Pediatric Healthcare
- Plant Pathogens and Fungal Diseases
- Childhood Cancer Survivors' Quality of Life
- Diverse Education Studies and Reforms
- Aquaculture disease management and microbiota
- Global Educational Reforms and Inequalities
- Esophageal Cancer Research and Treatment
- Cardiac Health and Mental Health
- Fungal and yeast genetics research
- Genetic and phenotypic traits in livestock
Temasek Life Sciences Laboratory
2023
National University of Singapore
1989-2023
Spaulding Rehabilitation Hospital
2023
Tseung Kwan O Hospital
2021
National University Health System
2012
University of California, Irvine
2007-2008
Polyketide natural products possess diverse architectures and biological functions share a subset of biosynthetic steps with fatty acid synthesis. The final transformation catalyzed by both polyketide synthases (PKSs) is most often carried out thioesterase (TE). synthetic versatility TE domains in fungal nonreducing, iterative PKSs (NR-PKSs) has been shown to extend Claisen cyclase (CLC) chemistry catalyzing C–C ring closure reactions as opposed thioester hydrolysis or O–C/N–C...
Abstract Background: An improved light activated disinfection technique utilizing a specific photosensitizer formulation, liquid optical‐conduit, oxygen‐carrier and energy of appropriate wavelength has been introduced recently. This study tested the efficacy this on ex vivo biofilms Enterococcus faecalis at two different stages maturation. Methods: Eighty‐five tooth sections were prepared endodontic biofilm E. grown within root canal. In stage 1, conventional (LAD), chemical disinfectant...
Type II polyketides are a class of natural products that include pharmaceutically important aromatic compounds such as the antibiotic tetracycline and antitumor compound doxorubicin. The type polyketide synthase (PKS) is complex consisting 5−10 standalone domains homologous to fatty acid (FAS). Polyketide ketoreductase (KR) provides regio- stereochemical diversity during reduction. How KR specifically reduces only C9 carbonyl group not well understood. cocrystal structures actinorhodin...
Rationale: Cultural and social isolation, microaggressions, few culturally linguistically diverse (CLD) mentors contribute to a lack of belonging on clinical education experiences (CEEs) for CLD Doctor Physical Therapy students. The purpose was investigate whether multiple mentor model including learner, their instructor (CI), could develop CI cross-cultural psychological capital (CC PsyCap) mentoring skills support learners CEEs. Methods: Three CIs were each matched with mentor. completed...
Abstract Background Heart failure (HF) evolves as a global pandemic and strains the over-stretched hospital service. Ineffective self-care remains key factor to explain avoidable admission. Patient empowerment is theory-based strategy optimize patients' changes for disease management [1]. Its cost-effectiveness enhance health service utilization has yet be determined. Purpose This was double-blind randomized controlled trial compare effects of 12-week program with didactic education on...