K. Amy Chen

ORCID: 0009-0008-9768-7764
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About
Contact & Profiles
Research Areas
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Neurogenesis and neuroplasticity mechanisms
  • Chinese history and philosophy
  • Single-cell and spatial transcriptomics
  • Cell Image Analysis Techniques
  • Mesenchymal stem cell research
  • Neuroscience and Neuropharmacology Research
  • Anesthesia and Neurotoxicity Research

Wenzhou Medical University
2023

University of Florida
2006

University of Florida Health
2005

To the extent that their fate choice and differentiation processes can be understood manipulated, neural stem cells represent a promising therapeutic tool for variety of neuropathologies. We have previously shown mature astrocytes possess cell attributes, give rise to neurons through formation multipotent neurosphere clones. Here we show relatively generated from neurospheres derived postnatal subependymal zone or cerebellar cortex undergo phenotypic transformation into coincides with...

10.1002/cne.20722 article EN The Journal of Comparative Neurology 2005-01-01

The mammalian brain is composed of diverse neuron types that play different functional roles. Recent single-cell RNA sequencing approaches have led to a whole taxonomy transcriptomically-defined cell types, yet type definitions include multiple cellular properties can offer additional insights into neuron's role in circuits. While the Patch-seq method investigate how transcriptomic relate local morphological and electrophysiological linking identities long-range projections major unresolved...

10.1101/2023.11.25.568393 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2023-11-27
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