Yunyan Dai

ORCID: 0009-0008-9872-5750
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Research Areas
  • Multiple Sclerosis Research Studies
  • melanin and skin pigmentation
  • Genomic variations and chromosomal abnormalities
  • Immune Response and Inflammation
  • Alcohol Consumption and Health Effects
  • Diet, Metabolism, and Disease
  • Cytokine Signaling Pathways and Interactions
  • Ferroptosis and cancer prognosis
  • Epigenetics and DNA Methylation
  • RNA regulation and disease
  • Viral Infections and Immunology Research
  • MicroRNA in disease regulation
  • Liver Disease Diagnosis and Treatment
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Immunotherapy and Immune Responses
  • Cancer-related molecular mechanisms research
  • T-cell and B-cell Immunology
  • RNA modifications and cancer
  • Systemic Lupus Erythematosus Research

Shanxi Academy of Medical Sciences
2024-2025

Shanxi Medical University
2024-2025

Karolinska Institutet
2001-2002

Karolinska University Hospital
2001-2002

Hepatocellular carcinoma (HCC) is the sixth most common cancer globally and primary cause of death in cases, with significant public health concern worldwide.Despite overall decline incidence mortality rates HCC recent years years, emergence metabolic liver disease-related causing heightened concern, especially countries like United States, Kingdom, P.R. China.The escalation attributed to a combination factors, including genetic predisposition, lifestyle choices, changes living...

10.2147/jhc.s450460 article EN cc-by-nc Journal of Hepatocellular Carcinoma 2024-03-01

The proinflammatory cytokine interferon (IFN)-γ has been shown to influence the course of multiple sclerosis (MS). IFN-γ (IFNG) contains a multiallelic dinucleotide repeat in intron l. To investigate whether alleles at this locus susceptibility MS, we performed linkage and familial association analyses on 100 sibling pairs from four Nordic countries, case-control analysis 220 intermediately disabled sporadic MS patients 266 controls. determine effect polymorphism disease outcome, compared...

10.1177/135245850100700304 article EN Multiple Sclerosis Journal 2001-06-01

Summary In recent years, numerous reports have described the diverse roles of CD40–CD40 ligand receptor–ligand pair. The interaction these two cell‐surface molecules regulates both humoral and cell‐mediated immune functions. Because CD40 is known to be highly expressed on peripheral blood mononuclear cells (PBMC) multiple sclerosis (MS) patients, because activated helper T expressing been found in brain sections MS but not those normal controls, protein believed involved development. We...

10.1046/j.1365-2370.2002.00270.x article EN European Journal of Immunogenetics 2002-03-25

Background Elevated evidence suggests that KIF20A plays an important role in hepatocellular carcinoma (HCC) progression. Nevertheless, the underlying mechanism by which promotes HCC cell growth are not well understood. Methods Using TCGA-LIHC RNAseq and GEO datasets, we assessed expression patient survival hepatitis B virus (HBV)-related HCC. Mutant CNV analysis were performed to evaluate genetic alteration of PPI network GSEA enrichment was utilized for analyzing KIF20A-related genes...

10.3389/fcimb.2024.1497427 article EN cc-by Frontiers in Cellular and Infection Microbiology 2024-11-18
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