A5093077389- Colorectal Cancer Treatments and Studies
- Genetic factors in colorectal cancer
- Gastric Cancer Management and Outcomes
- Cancer Genomics and Diagnostics
- Sarcoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Colorectal Cancer Screening and Detection
- Tumors and Oncological Cases
- Cancer Research and Treatments
- RNA modifications and cancer
- Pancreatic and Hepatic Oncology Research
- Barrier Structure and Function Studies
- Pancreatitis Pathology and Treatment
- Soft tissue tumor case studies
- Immune Cell Function and Interaction
- Cancer Immunotherapy and Biomarkers
- Cancer Cells and Metastasis
- Hepatocellular Carcinoma Treatment and Prognosis
AC Camargo Hospital
2024-2025
ORCID
2024
Instituto de Oncologia do Paraná
2024
Gastric cancer (GC) remains a formidable global health challenge, ranking among the top-five causes of cancer-related deaths worldwide. The majority patients face advanced stages at diagnosis, with mere 6% five-year survival rate. First-line treatment for metastatic GC typically involves fluoropyrimidine and platinum agent combination; yet, predictive molecular markers have proven elusive. This review navigates evolving landscape biomarkers, specific focus on Claudin 18.2 (CLDN18.2) as an...
Proteinase 3 (PRTN3) has been linked to the progression of different cancer types. In this study, expression and cell biological function PRTN3 were investigated in gastric (GC) assess its role GC progression. The levels 20 pairs tissues detected via quantitative real-time reverse transcription polymerase chain reaction (qRT-PCR) Western blotting, while immunohistochemical staining was used 47 tissue samples. effects stable lentivirus-mediated knockdown on proliferative, cycle, apoptotic...
Background In Brazil, 75% of the population is covered by public health insurance (PubHIn), and rest pay for private (PrivHIn). The impact type on clinical presentation Brazilian patients diagnosed with soft tissue sarcoma (STS) unknown. We aim to describe characteristics at diagnosis STS, stratifying them insurance, evaluate symptom-diagnosis -treatment intervals. Methods Observational, retrospective cohort, single-center study conducted in a cancer center that admits both patients. Medical...
ABSTRACT Introduction: Desmoid Tumors (DT) are rare neoplasms with higher incidence in younger women. Methods: Retrospective, single-center analysis of patients DT. Variables were age, sex, biopsy, treatment and recurrence. The disease-free survival (DFS) was calculated the Kaplan-Meier method. Results: 242 evaluated, mean age 34 years, 70.7% women, 44.4% originated trunk/abdomen 54.5% had size > 5cm. Surgery performed 70.2%, 31% negative margin only 57% previous biopsy. Recurrence rate...
173 Background: Precision oncology has changed clinical practice in metastatic colorectal cancer (mCRC). However, there is little data about molecular epidemiology of mCRC Brazil. Our study aims to create a nation-wide database develop future projects the Oncoclinicas Group. Methods: This was an observational, retrospective, and multicenter study. Anonymized medical records adult patients (18 years or older) with from January 2019 July 2023 were reviewed. All specimens centrally reviewed our...
Background: The association of age at onset CRC and prevalence KRAS G12C mutation is unclear; Methods: Retrospective multicenter study evaluating metastatic patients from January 2019 to July 2023 treated Oncoclinicas units, tested for tissue-based KRAS/NRAS BRAF mutations in a centralized genomics lab. Mismatch repair (MMR) status was retrieved different labs electronic medical records, as were patient demographics (age, gender) tumor sidedness. Chi-square test used examine the between...