Dermatophytes are most common infectious agents causing superficial mycosis worldwide. A number of topical as well systemic antifungal drugs available for treatment dermatophytosis. Superficial caused by dermatophytes can be easily treated or oral drugs, but in the course time, an increased failure cases appearing. Possible cause could poor patient compliance, drug penetration into affected lesion, and also resistance dermatophytes. The aim this study is to investigate minimum inhibitory...

Efficient gene transfer to muscle stem cells (satellite cells) has not been achieved despite broad transduction of skeletal by systemically administered adeno-associated virus serotype 2/9 (AAV-9) in mice. We hypothesized that cellular migration during fetal development would make satellite accessible for following utero intravascular injection. injected AAV-9 encoding green fluorescent protein (GFP) marker into the vascular space mice ranging ages from post-coital day 12 (E12) postnatal 1...

Dermatophytosis is a major health related problem in areas with high humidity, overpopulation and poor hygienic conditions. Treatment options are topical as well systemic antifungal drugs. But during course of time dermatophytes have also evolved drug resistance for single multiple drugs simultaneously. Therefore it became necessary to find out susceptibility dermatophytes. In this study we using disc diffusion method testing. To pattern among 80 patients all age group clinical diagnosis...

Presently, in vivo methods to efficiently and broadly transduce all major cell types throughout both the central (CNS) peripheral adult nervous system (PNS) are lacking. In this study, we hypothesized that during early fetal development neural populations, including stem cells (NSCs), may be accessible for gene transfer via open groove. To test hypothesis, injected lentiviral vectors encoding a green fluorescent protein (GFP) marker into murine amniotic cavity at embryonic day 8. This method...

Aeromanas salmonicida belonging to the genus Aeromonas is a common pathogen that causes furunculosis and septicemia in variety of fishes. It infects cold blooded vertebrates living at low temperature mainly salmonid fish hence named salmonicida. considered be pathogen, non-pathogenic for humans as it cannot grow 37ºC. However, In our laboratory culture plates, blood bottle broths were incubated twice 37ºC each time same type colonies isolated which identified A. samonicida by Vitek 2 compact...

Drug resistance is a burning issue for bacterial isolates and in- appropriate use of antibiotics one the most important factors that could affect increasing patterns resistance. A predictable profile antibiotic sensitivity will be great help clinicians to start empirical treatment. Hence periodical monitoring their susceptibility pattern important. Various clinical samples were obtained from 70 subjects various departments Hospitals which are associated with Dr. S. N. Medical College,...

Fungal infections of hospital origin have been gaining importance in recent years due to their progressive increase with high rate morbidity and mortality. Our study reports the results environmental surveillance fungi specific areas two tertiary care hospitals Dr. S.N. Medical College, Jodhpur-Rajasthan. Study was conducted from January2015 2016. Samples air local were collected on a monthly basis. The sampling done by passive sedimentation method petriplates containing Sabouraud's dextrose...

Embryologic events in mammalian myogenesis remain to be fully defined. Recent evidence supports the presence of a common progenitor arising dermomyotome that gives rise both embryologic and adult muscle postnatal myogenic stem cells (satellite cells). In this study, we utilize technique early intra-amniotic gene transfer target nascent progenitors as they traverse primitive streak before formation dermomyotome. This robustly transduced epaxial hypaxial groups. Marker expression is observed...

Abstract Objective: Dermatophytosis is a type of superficial mycosis affecting skin, hair and nails. The disease becoming prevalent in India. With antifungal formulations containing potent steroids also due to resistance the clinical presentation changing. In Skin OPD many cases dermatophytosis are being encountered with an atypical that cannot be diagnosed only on ground. These fungal infections mimic pictures non-infectious conditions require microbiological evaluation for confirmation....

Infection is still noted to be one of the major complications in treatment fractures. Infections are associated with prolonged hospital stay, leading higher cost, morbidity and mortality, particularly when infecting agents multidrug resistant. To compare incidence infective their resistance pattern between post-operative closed open fracture wounds. In this particular study 125 patients all age group were enrolled exclusion history diabetes mellitus, chronic steroid therapy, chemotherapy HIV...

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<br><i>Nocardia</i> spp. are filamentous Gram positive bacteria that ubiquitous soil saprophytes. The majority of nocardial infections occur in severely immunocompromised patients who particularly susceptible to pulmonary disease and dissemination. Extrapulmonary nocardiosis is relatively common can through hematogenous dissemination or a contiguous spread necrotizing pneumonitis. Primary cutaneous soft tissue result from traumatic injury the skin involves contamination with soil. After...

In this study, we are trying to find out viral aetiology in paediatric age group patients from 1 month 15 years of Western Rajasthan region.A total 105 were recruited into study. CSF samples collected and processed by multiplex real-time PCR for detection various predefined panels agents. ELISA was also done all dengue, JE, measles mumps.A 32 tested positive Viral detected study Adenovirus (n ​= ​2), EBV ​1), HHV-1 ​10), HHV-6 (N ​5), Parechovirus Parvovirus B19 ​7), Dengue ​2) Measles ​1)....

Objective: India’s national coronavirus disease 2019 (COVID-19) vaccination programs started during January 2021 and prioritized health-care workers (HCWs). In this study, we are attempting to measure post-vaccination product-specific (ChAdOx1_nCoV-19/COVISHIELD) COVID-19 vaccine effectiveness among vaccinated hospital HCWs also assess symptoms in with reverse transcription-polymerase chain reaction (RT-PCR) confirmed severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) infection....

The aim of the work was to compare acceptance and feasibility high add spectacles over other low vision aids (telescope magnifiers) in patients tertiary eye care centres western India. Materials used included visual acuity charts, pinhole, retinoscope trial lenses, slit lamp, indirect ophthalmoscope, assessment equipment optical aids. Retrospectively, 128 eyes from patient prescriptions who reported OPD, different ophthalmological set-ups, India were studied. subjects enrolled irrespective...

Acute Febrile Encephalopathy is a clinical term used to describe patients presenting with short febrile illnesses altered mental states. Demographic distribution plays an essential role in the diagnosis of viral etiologies. One hundred ve suspected AFE cases were enrolled study. A detailed history by predesigned performa and laboratory investigations was obtained for data collection. Viral etiology diagnosed 32 (30.48%) cases. The male female ratio 1.39:1. Total 56.25% positive from lower...

Acute febrile encephalopathy is a term commonly used to identify the condition in which altered mental status either accompanies or follows short illness. Japanese encephalitis (JE) and Dengue are arboviral diseases that common tropical countries. Viruses of Flavirdae family neurotropic like JE virus however; does not cause neurological diseases. One hundred five patients suspected AFE between age one month 15 years were enrolled study. Out them 32 (30.48%) cases showed evidence viral...