A5102759574- Craniofacial Disorders and Treatments
- Cleft Lip and Palate Research
- Tracheal and airway disorders
- Orthodontics and Dentofacial Orthopedics
- Reconstructive Surgery and Microvascular Techniques
- Oral and Maxillofacial Pathology
- Dental Radiography and Imaging
- Reconstructive Facial Surgery Techniques
- Liver Disease Diagnosis and Treatment
- Adipose Tissue and Metabolism
- Temporomandibular Joint Disorders
- Facial Trauma and Fracture Management
- Dental Implant Techniques and Outcomes
- Peroxisome Proliferator-Activated Receptors
- Diet and metabolism studies
- Anatomy and Medical Technology
- Facial Nerve Paralysis Treatment and Research
- Endodontics and Root Canal Treatments
- Oral microbiology and periodontitis research
- Bone Tumor Diagnosis and Treatments
- Facial Rejuvenation and Surgery Techniques
- RNA modifications and cancer
- Medical and Biological Sciences
- Dental Anxiety and Anesthesia Techniques
- Growth Hormone and Insulin-like Growth Factors
Chinese University of Hong Kong
2012-2025
Prince of Wales Hospital
2025
Karolinska Institutet
2003-2019
Karolinska University Hospital
2009-2019
University of Hong Kong
2005-2017
Prince Philip Dental Hospital
1987-2012
HKU-Pasteur Research Pole
2008
University of Hong Kong - Shenzhen Hospital
2006
National Medical Research Center of Dentistry and Maxillofacial Surgery
2005
Royal Prince Alfred Hospital
1996
Purpose This paper aims to illustrate a number of instances where RP and associated technology has been successfully used for medical applications. Design/methodology/approach A case studies are presented, illustrating different uses technology. These have analysed in terms how the applied order solve related problems. Findings It was found that helpful ways However, numerous limitations establish should develop future. Practical implications can help problems, but must evolve if it is be...
PPARδ is involved in the inflammatory response and its expression induced by cytokines, however, limited knowledge has been produced regarding regulation. Since recent findings have shown that microRNAs, which are small non-coding RNAs regulate gene expression, immune response, we set out to investigate whether can be regulated microRNAs expressed monocytes. Bioinformatic analysis identified a putative miR-9 target site within 3'-UTR of was subsequently verified functional using reporter...
The aim of this study was to identify genes for hepatic fuel metabolism with a gender-differentiated expression and determine which these that might be regulated by the female-specific secretion GH. Effects gender continuous infusion GH male rats were studied in liver using cDNA microarrays representing 3200 genes. Sixty-nine transcripts displayed higher levels females, 177 males. portion GH-regulated same (30%) within two groups gender-specific had involved metabolism, indicating have...
Background: Oral candidiasis is a common problem in compromised patients. Although several non‐ albicans Candida species have emerged as pathogens the majority of candidal infections are caused by . Morphogenesis from blastospore to filamentous phase, and production secretory aspartyl proteinases (SAP) two major virulence attributes these opportunistic yeast. Histopathology oral characterized fungal invasion superficial epithelium although invasive potentials different vary. Computerized...
CD36 is a multiligand receptor involved in various metabolic pathways, including cellular uptake of long-chain fatty acids. Defect function or expression can result dyslipidemia insulin resistance. We have previously shown that female-predominant rat liver. In the present study, hormonal and nutritional regulation hepatic was examined male female rats. Since alternative transcription start sites been described murine human Cd36, we investigated whether transcripts are differentially...
MicroRNAs (miRNAs) are short non-coding RNAs playing an important role in post-transcriptional regulation of gene expression. We have previously shown that hepatic transcript profiles different between males and females; some these differences under the growth hormone (GH); mild starvation diminishes differences. In this study, we tested if miRNAs regulated a similar manner. Using microarrays, miRNA screening was performed to identify sex-dependent rat liver. Out 324 unique probes on array,...
Abstract Background Genes involved in hepatic metabolism have a sex-different expression rodents. To test whether male and female rat livers differ regarding lipid carbohydrate metabolism, whole-genome transcript profiles were generated these complemented by measurements of glycogen content, fatty acid (FA) oxidation rates glucose output (HGO). The latter was determined perfusates from situ perfusion livers. These also analysed using nuclear magnetic resonance (NMR) spectroscopy to identify...
The amount of intra-thoracic fat, which mediastinal adipose tissue comprises the major depot, is related to various cardiometabolic risk factors. Autopsy and imaging studies indicate that depot in adult humans could contain brown (BAT). To gain a better understanding this fat we examined possible BAT characteristics human comparison with subcutaneous tissue. Adipose biopsies from thoracic depots were obtained during open-heart surgery 33 subjects (26 male, 63.7±13.8 years, body mass index...