A5046217304- Molecular Sensors and Ion Detection
- Electrochemical Analysis and Applications
- Trace Elements in Health
- Advanced biosensing and bioanalysis techniques
- Metal complexes synthesis and properties
- Drug Transport and Resistance Mechanisms
- Innovation and Socioeconomic Development
- Free Radicals and Antioxidants
- Magnetism in coordination complexes
- Advanced MRI Techniques and Applications
- Analytical Chemistry and Sensors
- Microfinance and Financial Inclusion
- Chemotherapy-induced organ toxicity mitigation
- Lanthanide and Transition Metal Complexes
The University of Sydney
2012-2021
In-Q-Tel
2014
Two major issues which hamper the use of anticancer drug cisplatin are development cancer cell resistance and its nephrotoxicity. One possible mechanism by is reported to develop a reduction in uptake across membrane. While passive has long been cited as an important contribution, far greater attention given active modes uptake, particularly recent research. Using unilamellar lipid vesicles together with stopped-flow kinetic method we show here that permeability coefficient increases...
Ratiometric probe for Cu(<sc>i</sc>) reveals influence of cisplatin on mitochondrial copper homeostasis.
Platinum complexes remain frontline anticancer therapies, even after 50 years of usage in clinical applications. However, there is still a lack methodology to robustly detect and quantify these biological fluids. We report here fluorescent sensor array comprising six sensors that demonstrates progress toward the detection platinum levels chemotherapy patients. Linear discriminant analysis was performed examine each multidimensional data set, able discriminate from other biologically relevant...
We report here FDCPt1, a novel selective fluorescent sensor for monofunctional platinum species. In the presence of such species, FDCPt1 exhibits 70-fold increase in fluorescence emission, and can be used to monitor metabolism Pt(II)-based complexes colorectal cancer cells. This probe is therefore expected valuable studying changes Pt coordination distribution during chemotherapy.
A fluorescent sensing array based on analogues of Calcein Blue is able to classify toxic heavy metals in water.
This paper provides an overview of the Bloom micro-distribution programme, initiative spearheaded by Mars Catalyst and Wrigley Confectionery Philippines that engages female sellers in Manilla, Philippines, as distributors confectionery products. The case includes assessment multi-dimensional impact on 300 well challenges project faces. Data for this were drawn from documents provided staff, key informant interviews, surveys conducted 2016; programme remains active.