A5016004380- Orthopaedic implants and arthroplasty
- Bone Tissue Engineering Materials
- Immune Cell Function and Interaction
- Liver Disease Diagnosis and Treatment
- Breast Cancer Treatment Studies
- CAR-T cell therapy research
- biodegradable polymer synthesis and properties
- Cancer Treatment and Pharmacology
- Reconstructive Surgery and Microvascular Techniques
- Biochemical Analysis and Sensing Techniques
- Abdominal vascular conditions and treatments
- Head and Neck Anomalies
- Pediatric Hepatobiliary Diseases and Treatments
- Enhanced Recovery After Surgery
- Cancer-related Molecular Pathways
- Endoplasmic Reticulum Stress and Disease
- Catalysis and Oxidation Reactions
- Global Cancer Incidence and Screening
- Advanced ceramic materials synthesis
- Liver Disease and Transplantation
- HER2/EGFR in Cancer Research
- Cardiac, Anesthesia and Surgical Outcomes
- Polyoxometalates: Synthesis and Applications
- Otolaryngology and Infectious Diseases
- Phytochemicals and Antioxidant Activities
Dong-A University
2004-2025
Taipei Veterans General Hospital
2025
Breast Center
2011
ErbB3 is markedly overexpressed in breast cancer cells and associated with resistance metastasis. Additionally, expression levels are positively correlated low densities of tumor-infiltrating lymphocytes, a marker poor prognosis. Consequently, promising therapeutic target for immunotherapy. Here, we report the generation ErbB3-targeted chimeric antigen receptor (CAR)-modified natural killer (NK) by transducing cord blood-derived primary NK using vsv-g envelope-pseudotyped lentiviral vectors....
Background: Metformin, a drug prescribed for patients with type 2 diabetes, has potential efficacy in enhancing antitumor immunity; however, the detailed underlying mechanisms remain to be elucidated.Therefore, we aimed identify inhibitory molecular of metformin on programmed death ligand 1 (PD-L1) expression cancer cells and (PD-1) immune cells.Methods: We employed luciferase reporter assay, quantitative real-time PCR, immunoblotting analysis, immunoprecipitation ubiquitylation assays,...
The current work was the first to conduct tyrosinase inhibition and antioxidant properties as well phenolic phytochemicals in seeds of Korean perilla species such cultivated wild types. 80% methanol extract (80 μg/mL) this source showed potent biological activities, especially, P. frutescens var. had highest antityrosinase effects with 86 87%. To investigate phenolics on their capacities, above chromatographed, which yielded six compounds, including caffeic acid (1), rosmarinic...
Clinical OtolaryngologyVolume 42, Issue 5 p. 1087-1091 Correspondence: Our Experience Application of ultrasound-guided pigtail catheter drainage for abscesses in the head and neck B.Y. Joo, Joo Department Otolaryngology-Head Neck Surgery, Dong-A University College Medicine, Busan, KoreaSearch more papers by this authorA.L. Jang, A.L. Jang Medical Engineering, Graduate School, authorJ.H. Lee, J.H. Lee Radiology, authorH.S. Park, H.S. Park authorM.K. Kang, M.K. Kang authorJ.C. Hong,...
Poly ε-caprolactone(PCL)/hydroxyapatite(HA) composite scaffolds were fabricated by particulate leaching and freeze drying routes with different HA content. Porosity was decreased addition, while mean pore size maintained at around porogen regardless of Compressive modulus increased increasing In this study, the optimum content 40% in weight against PCL to obtain highest compressive keeping porosity above 85%. apparently enhanced proliferation osteoblast-like MG63 cells PCL/HA scaffolds....
Degradation characteristics of calcium metaphosphate (CMP) ceramics substituted by 5, 10, 15, 20 mol% NaPO3 and KPO3, respectively, was evaluated in revised simulated body fluid (R-SBF) measuring the weight change, flexural strength, crystalline phases, surface morphology with immersion period. The loss CMP KPO3 significantly higher than that NaPO3. KCa(PO3)3–CMP samples due to dissolution KCa(PO3)3 phase. strength NaCa(PO3)3–CMP increased, however, decreased KCa(PO3) phase formed a pore...
Porous calcium metaphosphate granules for bone fillers were prepared by starch consolidation with baking powder and surfactant. Paste foaming was the mixing of water various amount (10~20㎛ size), where solid contents 30%, 45%, 60% paste. In order to obtain optimum micro/macro porous structure, appropriate surfactant at a fixed content examined. examine on pore morphology, added 60, 180, 300 wt% paste starch. And then, in investigate effect 0.035, 0.1, 0.16 weight powder. Foaming conducted...
Background: There are many clinical and molecular factors used to predict outcomes in patients with malignant lymphomas. Some studies have shown that serum ferritin levels correlated tumor mass closely followed disease activity hematologic malignancies such as lymphoma acute leukemia. And has frequently been a surrogate marker for systemic iron stores, but may also be elevated specific circumstances without excess inflammation. Nevertheless, actual practice, the lymphoma, who anemic high...