A5073083552- Cancer therapeutics and mechanisms
- Luminescence Properties of Advanced Materials
- Synthesis and biological activity
- Synthesis and Characterization of Heterocyclic Compounds
- Advanced battery technologies research
- Quinazolinone synthesis and applications
- Glass properties and applications
- Electrocatalysts for Energy Conversion
- Analytical Chemistry and Sensors
- Lung Cancer Treatments and Mutations
- Phenothiazines and Benzothiazines Synthesis and Activities
- Advanced Breast Cancer Therapies
- Dendrimers and Hyperbranched Polymers
- Radiation Detection and Scintillator Technologies
- Water Quality Monitoring and Analysis
- Advanced oxidation water treatment
- Protein Degradation and Inhibitors
- CO2 Reduction Techniques and Catalysts
- Solid State Laser Technologies
- Chemical Synthesis and Analysis
- Cancer-related Molecular Pathways
- Luminescence and Fluorescent Materials
Southern Medical University
2015-2025
Shenyang University of Chemical Technology
2024-2025
Jiangmen Wuyi Traditional Chinese Medicine Hospital
2025
Ni-based bimetallic alloys have superior physiochemical characteristics compared to monometallic Ni. In this study, a new type of low cost NimCon (n + m = 4) electrocatalysts with high active surface were synthesized on Ti substrate through hydrogen evolution assisted electrodeposition method. The as-prepared characterized by XRD, EDS, and SEM. It was revealed that the composition, morphology, as well crystal phase structure significantly changed increased content cobalt. Electrochemical...
CDK2 and CDK9 play pivotal roles in cell cycle progression gene transcription, respectively, making them promising targets for cancer treatment. Herein, we discovered a series of N4-(substituted thiazol-2-yl)-N2-(4-substituted phenyl)pyrimidine-2,4-diamines as highly potent CDK2/9 dual inhibitors. Especially, compound 20a significantly inhibited (IC50 = 0.004 μM) 0.009 μM), achieving 1000- 2800-fold improvement over lead 11, demonstrating broad antitumor efficacy. Mechanistic studies...
Abstract Upconversion luminescence materials hold significant promise for various applications, including lasers, solar cells, anti-counterfeiting technology, biological labeling, and sensor technology. GdPO 4 stands out as a highly promising upconversion host material thanks to its exceptional chemical thermal stability. While the properties of Er 3+ Yb co-doped are indeed influenced by crystal environment rare earth ions within matrix, fundamental understanding how pH high concentration...