A5027455541- Neonatal Respiratory Health Research
- Congenital Diaphragmatic Hernia Studies
- Human Health and Disease
- Pediatric health and respiratory diseases
- Asthma and respiratory diseases
- Legionella and Acanthamoeba research
- Food Allergy and Anaphylaxis Research
- Pulmonary Hypertension Research and Treatments
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Lysosomal Storage Disorders Research
- Myasthenia Gravis and Thymoma
- Pharmaceutical studies and practices
- Vibrio bacteria research studies
- Phonocardiography and Auscultation Techniques
- Calcium signaling and nucleotide metabolism
- Soft tissue tumor case studies
- Health and Medical Studies
- Cellular transport and secretion
- Infant Nutrition and Health
- Medical Imaging and Pathology Studies
- Diverticular Disease and Complications
- Glycogen Storage Diseases and Myoclonus
- Dermatological and Skeletal Disorders
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Cholangiocarcinoma and Gallbladder Cancer Studies
Centre International de Recherche en Infectiologie
2023-2024
Université Claude Bernard Lyon 1
2023-2024
Inserm
2023-2024
École Normale Supérieure de Lyon
2023-2024
Centre National de la Recherche Scientifique
2023-2024
Imperial College London
2019-2023
Centre Hospitalier d'Arras
1979
Increased expression of CLIC4 (chloride intracellular channel 4) is a feature endothelial dysfunction in pulmonary arterial hypertension, but its role disease pathology not fully understood.To identify effectors and evaluate strategies targeting signaling hypertension.Proteomic analysis CLIC4-interacting proteins human artery cells identified regulators endosomal trafficking, including Arf6 (ADP ribosylation factor 6) GTPase activating clathrin, while overexpression affected protein...
Host actin cytoskeleton is often targeted by pathogenic bacteria through the secretion of effectors. Legionella pneumophila virulence relies on injection largest known arsenal bacterial proteins, over 300 Dot/Icm type 4 system effectors, into host cytosol. Here, we define functional interactions between VipA and LegK2, two effectors with antagonistic activities towards polymerization that have been proposed to interfere endosomal pathway. We confirmed prominent role LegK2 effector in...
ABSTRACT Host actin cytoskeleton is often targeted by pathogenic bacteria through the secretion of effectors. Legionella pneumophila virulence relies on injection largest known arsenal bacterial proteins, over 300 Dot/Icm Type 4 Secretion System effectors, into host cytosol. Here we define functional interactions between VipA and LegK2, two effectors with antagonistic activities towards polymerization that have been proposed to interfere endosomal pathway. We confirmed prominent role LegK2...
The analysis of electrophysiological signals via a recursive segmentation technique is presented. This method leads to an adaptive time reference linked the fluctuations biorhytms. numerical process yields filtered estimation signal as well its first derivative. simplicity equations involved readily conception microprocessor-based structure. used analyze thoracic impedance waveforms newborn. cyclic nature this made use generate LISSAJOUS patterns which characterize each respiratory cycle....