- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- Physiological and biochemical adaptations
- Aquaculture disease management and microbiota
- Developmental Biology and Gene Regulation
- Advanced biosensing and bioanalysis techniques
- Evolution and Genetic Dynamics
- Aquaculture Nutrition and Growth
- Zebrafish Biomedical Research Applications
- Congenital heart defects research
- CRISPR and Genetic Engineering
University of Bergen
2023-2024
Eötvös Loránd University
2019
Abstract The maternal-effect mutation ichabod ( ich ) results in ventralized zebrafish embryos due to impaired induction of the dorsal canonical Wnt-signaling pathway. While previous studies linked phenotype reduced ctnnb2 transcript levels, causative remained unidentified. Using long-read sequencing, we discovered that stems from insertion a non-autonomous CMC-Enhancer/Suppressor-mutator (CMC-EnSpm) transposon 3’UTR gene. Through reporter assays, demonstrate while wild type mRNAs exhibit...
Gilthead seabream (Sparus aurata) is an important species in Mediterranean aquaculture. Rapid intensification of its production and sub-optimal husbandry practices can cause stress, impairing overall fish performance raising issues related to sustainability, animal welfare, food safety. The advent next-generation sequencing technologies has greatly revolutionized the study stress biology, allowing a deeper understanding molecular responses. Here, we characterized for first time, using...
Maternal genes have a pivotal role in regulating metazoan early development. As such their functions been extensively studied since the dawn of developmental biology. The temporal and spatial dynamics transcripts thoroughly described model organisms undergoing heavy investigations. Yet, less is known about evolutionary changes shaping presence within diverse oocytes. Due to unique maternal inheritance pattern, high degree predicted be present when it comes expression. Insofar only limited...
The regeneration of paired appendages in certain fish and amphibian lineages is a well established extensively studied regenerative phenomenon. teleost fin comprised proximal endoskeletal part (considered homologous to the Tetrapod limb) distal exoskeletal one, these two parts form their bony elements through different ossification processes. In past decade, significant body literature has been generated about biology zebrafish. However, it still not clear if this knowledge can be applied...