A5102917641- Genetic Associations and Epidemiology
- Dementia and Cognitive Impairment Research
- Liver Disease Diagnosis and Treatment
- Diet and metabolism studies
- Adipokines, Inflammation, and Metabolic Diseases
- Climate Change and Health Impacts
- Blind Source Separation Techniques
- Phonocardiography and Auscultation Techniques
- Nutritional Studies and Diet
- Rheumatoid Arthritis Research and Therapies
- Radiomics and Machine Learning in Medical Imaging
- Air Quality Monitoring and Forecasting
- Health disparities and outcomes
- Spectroscopy and Chemometric Analyses
- Folate and B Vitamins Research
- Parkinson's Disease Mechanisms and Treatments
- Air Quality and Health Impacts
- Biomarkers in Disease Mechanisms
Shanghai Ninth People's Hospital
2024-2025
Shanghai Jiao Tong University
2010-2025
Henan Provincial People's Hospital
2025
Zhengzhou University
2025
Zhengzhou University of Light Industry
2025
Introduction Previous researches have often underestimated the diversity and combined effects of risk factors for Parkinson’s disease (PD). This study aimed to identify how multiple modifiable collectively impact PD. Methods The included 452,492 participants from UK Biobank, utilizing genetic data 255 phenotypic variables. A broad exposure association was conducted across seven domains: socioeconomic status, medical history, psychosocial factors, physical measures, early life, local...
Our primary objective was to assess the association between joint exposure various air pollutants and risk of ischemic stroke (IS) modification genetic susceptibility.
<title>Abstract</title> <bold>Background</bold>: The aim of this study was to investigate the relationship between minerals in domestic water and incidence rheumatoid arthritis (RA). <bold>Methods</bold>: This longitudinal observational included 434,958 British individuals from United Kingdom. population consisted RA-free participants with complete information on minerals, genetic data, lifestyle habits, physical measurements at baseline. baseline assessment conducted 2006 2010, follow-up...
<h3>Background:</h3> White matter damage is closely associated with cognitive and psychiatric symptoms prevalent in cerebral small vessel disease (CSVD); although the pathophysiological mechanisms involved CSVD remain elusive, inflammation plays a crucial role. We sought to investigate relationship between systemic markers imaging of CVSD, namely white hyperintensity (WMH) microstructural injury. <h3>Methods:</h3> conducted study involving both cross-sectional longitudinal data from UK...
Abstract Currently, the relationship between household size and incident dementia, along with underlying neurobiological mechanisms, remains unclear. This prospective cohort study was based on UK Biobank participants aged ≥ 50 years without a history of dementia. The linear non-linear longitudinal association assessed using Cox proportional hazards regression restricted cubic spline models. Additionally, potential mechanisms driven by brain structures were investigated We included 275,629...
The Colonic manometry is an important technique to evaluate human colonic motor functions, which are critical for doctors understand the pathology of intestinal diseases like slow transit constipation (STC) and inertia (CI). However, in obtained pressure signals, several patterns activities as well noises mixed together, made it difficult observe information people really needed. In this article, a new method was proposed extract motility from so that researchers could study them thoroughly....