Jorge Lázaro

ORCID: 0009-0009-5732-9150
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About
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Research Areas
  • Microbial Metabolic Engineering and Bioproduction
  • Gene Regulatory Network Analysis
  • Viral Infectious Diseases and Gene Expression in Insects
  • Bioinformatics and Genomic Networks
  • Process Optimization and Integration
  • Protein purification and stability
  • Biofuel production and bioconversion

Universidad de Zaragoza
2022-2025

ABSTRACT Metabolic models can be used to analyze and predict cellular features such as growth estimation, gene essentiality, product formation. divided into two main types: constraint-based kinetic models. Constraint-based usually account for a large subset of the metabolic reactions organism and, in addition reaction stoichiometry, these accommodate regulation constant flux bounds reactions. are mostly limited steady state it is challenging optimize competing objective functions. On other...

10.1101/2024.07.11.597182 preprint EN cc-by 2024-07-14

The current production of a number commodity chemicals relies on the exploitation fossil fuels and hence has an irreversible impact environment. Biotechnological processes offer attractive alternative by enabling manufacturing genetically modified microorganisms. However, this approach poses some important technical challenges that must be tackled to make it competitive. On one hand, design biotechnological is based trial-and-error approaches, which are not only costly in terms time money,...

10.3389/fmolb.2022.855735 article EN cc-by Frontiers in Molecular Biosciences 2022-04-27
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