Muhammad Esa

ORCID: 0009-0009-7331-3925
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Research Areas
  • Antibiotic Use and Resistance
  • Computational Drug Discovery Methods
  • Ethnobotanical and Medicinal Plants Studies
  • Pneumonia and Respiratory Infections
  • Essential Oils and Antimicrobial Activity
  • Biosensors and Analytical Detection
  • Synthesis and biological activity
  • Chemical synthesis and alkaloids
  • Insect Pest Control Strategies
  • Nanomaterials for catalytic reactions
  • Mental Health Research Topics
  • Polysaccharides Composition and Applications
  • Child and Adolescent Psychosocial and Emotional Development
  • Nanoparticles: synthesis and applications
  • Polysaccharides and Plant Cell Walls
  • Advanced biosensing and bioanalysis techniques
  • Silymarin and Mushroom Poisoning
  • Free Radicals and Antioxidants
  • Animal Diversity and Health Studies
  • Cholinesterase and Neurodegenerative Diseases
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Electrochemical Analysis and Applications
  • Alzheimer's disease research and treatments
  • Plant and fungal interactions
  • Antibiotic Resistance in Bacteria

Shaheed Benazir Bhutto University
2023-2025

University of Malakand
2024

Abbottabad University of Science and Technology
2024

King Saud University
2024

Sarhad University of Science and Information Technology
2024

China Pharmaceutical University
2024

Abasyn University
2024

Imam Abdulrahman Bin Faisal University
2024

Abstract: Alzheimer’s disease (AD), a neurodegenerative condition, continues to pose significant challenges modern medicine due the limited efficacy offered by current therapeutic modalities. With complex pathophysiology of AD, which includes tau protein accumulation, amyloid-β plaque formation, neuroinflammation, and synaptic dysfunction, novel drug-targeting sites must be identified. This study presents thorough evaluation drug targeting sites, with focus on these pathological...

10.2174/011570159x361867250313073624 article EN Current Neuropharmacology 2025-04-08

Abstract Silymarin-loaded zein polysaccharide core–shell nanoparticles (SZPCS-NPs) were synthesized where sodium alginate and pectin offer stability controlled release qualities to zein, a maize protein, having excellent biocompatibility. The present study is an attempt develop zein–silymarin nanostructures enhance water solubility, thereby improving bioavailability producing enhanced biological responses in living systems. SZPCS-NPs prepared using pH-induced antisolvent precipitation...

10.1515/gps-2024-0002 article EN cc-by Green Processing and Synthesis 2024-01-01

Abstract The current study attempted to synthesize methoxy-substituted Schiff’s bases, namely MK1 and MK2, evaluate their antidiabetic effects using in vitro , vivo molecular docking studies. Experimental animals (rat model) received the synthetic compounds, orally doses of 25 50 mg/kg body weight, respectively. When comparing compound MK2 at tested glibenclamide on day 28, diabetic rats’ blood glucose levels were nearly normal (139.02 121.23 mg/dL weight doses). IC for against α-glucosidase...

10.1515/chem-2024-0083 article EN cc-by Open Chemistry 2024-01-01

<title>Abstract</title> A prospective cohort study was designed to investigate the safety and effectiveness of escitalopram (10–20 mg) in treatment social anxiety disorder (SAD), with a focus on population district Nowshera, Khyber Pakhtunkhwa, Pakistan. The spanned eight weeks aimed assess impact patients diagnosed SAD. Hamilton Anxiety Rating Scale (HARS) employed by psychiatrists measure scores before after administration escitalopram. reducing SAD assessed treatment, using Wilcoxon...

10.21203/rs.3.rs-3909385/v1 preprint EN cc-by Research Square (Research Square) 2024-02-12

Abstract Background Local and indigenous communities of the Jandool Valley, Dir Lower District, in Northwest Khyber Pakhtunkhwa, Pakistan, rely on ethnoveterinary herbal formulations to treat their domestic animals. Insights into uses local botanical flora can direct investigation phytochemical screening. The present research is carried out with aim documenting expertise concerning various plant species used by population area for curing animal diseases ailments. Ethnoveterinary statistics...

10.21203/rs.3.rs-3988961/v1 preprint EN cc-by Research Square (Research Square) 2024-03-07

Antimicrobial resistance is now considered a global dilemma and threat to many antibiotics running in clinical practices. In Pakistan, its worst consequences appear rise day by day, especially hospital community-acquired healthcare settings. Khyber Pakhtunkhwa (KP) Peshawar, most of the Tertiary Care Hospitals, have big flow outpatients throughout country as well across border from Afghanistan, Iran, Middle Eastern countries. So, opportunities for cross infections, transmission Multidrug...

10.53560/ppasb(61-sp1)1013 article EN cc-by Proceedings of the Pakistan Academy of Sciences B Life and Environmental Sciences 2024-04-30

Antimicrobial resistance (AMR) is now a global pandemic and future threat to the existence of many clinical antibiotics. The excessive overuse in fisheries, poultries, dairy farms its irrational prescribing practices are key factors that lead us AMR explosions. current main research objective evaluate empirical ampicillin along with cloxacillin, which one running antibiotics practices, most tertiary care hospitals Khyber Pakhtunkhwa, Pakistan. In this study, attitude, sensitivity...

10.53560/ppasb(60-sp1)792 article EN cc-by Proceedings of the Pakistan Academy of Sciences B Life and Environmental Sciences 2023-01-17
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