A5000251191- Nanoplatforms for cancer theranostics
- Luminescence and Fluorescent Materials
- Supramolecular Chemistry and Complexes
- Photodynamic Therapy Research Studies
- Porphyrin and Phthalocyanine Chemistry
- Advanced biosensing and bioanalysis techniques
- Perovskite Materials and Applications
- Advanced Photocatalysis Techniques
- Molecular Sensors and Ion Detection
- Analog and Mixed-Signal Circuit Design
- Advanced Electrical Measurement Techniques
- Geological and Geochemical Analysis
- Health and Well-being Studies
- bioluminescence and chemiluminescence research
- Job Satisfaction and Organizational Behavior
- Analytical Chemistry and Sensors
- Geochemistry and Geologic Mapping
- Photoacoustic and Ultrasonic Imaging
- Healthcare Education and Workforce Issues
- Hydrocarbon exploration and reservoir analysis
East China University of Technology
2025
Nantong University
2022-2024
Guangzhou University
2024
Shanxi University of Traditional Chinese Medicine
2024
This review summarizes organic conjugated small-molecule photosensitizers with D–A, D–A–D and A–D–A structures in phototherapy applications, highlighting some effective molecular design strategies proposing future perspectives opportunities.
Synchronously improving the photothermal conversion efficiency and photodynamic activity of organic small molecule photosensitizers is crucial for their further wide application in cancer treatment. Recently, emerging A–D–A photosensitizer-based phototherapy systems have attracted great interest due to plentiful inherent merits. Herein, we propose a design strategy with synchronously enhanced reactive oxygen species (ROS) generation efficiencies. Side chain programming carried out three...
In the current work, we synthesized an A-D-A smallmolecule photosensitizer, denoted as DPTTIC, and a dual PEG-functionalized pillararene, WP5-8C-2PEG, used them to construct novel DPTTIC nanoparticles (NPs) displaying NIR II absorption. Under 980 nm-wavelength laser irradiation, NPs performed well in mild-temperature photothermal type I & photodynamic anti-tumor therapy.
Supramolecular coordination complexes formed by coordination-induced assembly not only avoid the loss of activity precursors but also provide an efficient way for controlled release, which can be further used in various fields biology such as drug delivery, cell imaging, and tumor treatment. In this work, a PtII metallaclip (4) was prepared from 4-[4-(1,2,2-triphenylvinyl)phenyl]pyridine (1), 5,10,15-triphenyl-20-(pyridin-4-yl)porphyrin (2), 90o Pt, glycol-chain-modified isophthalic acid (3)...
ABSTRACT The Upper Triassic black shales in the Sichuan Basin are formed three stages and predominantly situated at forefront of Longmenshan (LMS) thrust belt. These formations a result rapid subsidence events foredeep development an underfilled foreland basin, triggered by intense nappe movements LMS orogenic wedge during Late Triassic. lateral migration from northeast to southwest, suggests that occurred northeastern region early gradually shifted toward southwestern later ongoing...
A picowatt CMOS voltage reference with dual outputs is proposed and simulated in this paper based on a standard 65 nm process. To compensate for the leakage current caused by parasitic reverse-biased PN junctions, an approach employing gate transistors proposed. Maintaining maximal temperature coefficient (TC) of 20.40 ppm/°C across extended range −10∼155 °C achieved. Additionally, divider consisting diode-connected NMOS introduced to obtain lower output without shunting original branch or...
To assess abusive supervision and organizational silence among nurses investigate the mediating influence of psychological capital fear.
Platinum(II)-based metallacycles/cages have obtained tremendous attention due to their fascinating topology and wide range of applications, such as fluorescent materials, cell imaging, tumor treatment. In this work, a metallatetragon (1) was constructed from 4-(4-(1,2,2-triphenylvinyl)phenyl)pyridine (2) 90° cis-Pt(II) (Pt) in acetone through the strategy called "coordination driven self-assembly". Interestingly, co-assembly 1 poly(ethylene glycol)-modified tetraphenylethylene (TPE-PEG22),...
Abstract Phototheranostics continues to flourish in cancer treatment. Due the competitive relationships between these photophysical processes of fluorescence emission, photothermal conversion, and photodynamic action, it is critical balance them through subtle photosensitizer designs. Herein, provided a useful guideline for constructing A−D−A photosensitizers with superior phototheranostics performance. Various cyanoacetate group‐modified end groups containing ester side chains different...
Tumor-targeting phototheranostics has gradually developed as a powerful tool for the precise diagnosis and treatment of cancer. However, designs tumor-targeting agents with excellent multimodal phototherapy fluorescence imaging (FLI) capability, well very few components, are still scarce challenging cancer treatment. Herein, mitochondria-targeting system been constructed by combining designed amphiphilic pillararene WP5–2PEG–2TPP A–D–A fused-ring photosensitizer F8CA5. is attaching...
BODIPY photosensitizers have been integrated with a hypoxia-activated prodrug to achieve synergistic photodynamic therapy (PDT) and chemotherapy. A novel derivative BDP-CN was designed synthesized. It had two cyano groups make it complex well water-soluble pillar[5]arene. Their association constant calculated be (6.8±0.9)×106 M-1 . After self-assembly in water, regular spherical nanocarriers can formed; these were used encapsulate the tirapazamine (TPZ). displayed excellent activity complete...