A5102807493- Metalloenzymes and iron-sulfur proteins
- ATP Synthase and ATPases Research
- Cell Adhesion Molecules Research
- Microbial metabolism and enzyme function
- Advanced Glycation End Products research
- Pediatric health and respiratory diseases
- Pancreatic function and diabetes
- Genomics, phytochemicals, and oxidative stress
- Renal Diseases and Glomerulopathies
- Diabetes and associated disorders
- Coenzyme Q10 studies and effects
- Psoriasis: Treatment and Pathogenesis
- Contact Dermatitis and Allergies
- Dermatology and Skin Diseases
- Pharmacogenetics and Drug Metabolism
- Nuclear Structure and Function
Soonchunhyang University
2023-2024
Chosun University
1996
<title>Abstract</title> Kidney fibrosis is characterized by an aberrant extracellular matrix accumulation. Glutamyl-prolyl-tRNA synthetase 1 (EPRS1) a crucial enzyme involved in the synthesis of proline-rich proteins. However, its role kidney remains unclear. The present study found that EPRS1 expression levels were increased fibrotic kidneys patients and mice. We also fibroblasts proximal tubular epithelial cells major sources based on single-cell analysis immunostaining kidneys. C57BL/6...
Abstract Kidney fibrosis causes irreversible structural damage in chronic kidney disease and is characterized by aberrant extracellular matrix (ECM) accumulation. Although glutamyl-prolyl-tRNA synthetase 1 (EPRS1) a crucial enzyme involved proline-rich protein synthesis, its role remains unclear. The present study revealed that EPRS1 expression levels were increased the fibrotic kidneys of patients mice, especially fibroblasts proximal tubular epithelial cells, on basis single-cell analysis...
Background Chronic kidney disease (CKD)-associated pruritus is a severe distressing condition that frequently occurs in patients undergoing dialysis. In this study, the profile of skin microbiome was analyzed to understand underlying etiology and potential treatments. Methods Seventy-six end-stage (ESKD) (hemodialysis, 40; peritoneal dialysis, 36) 15 healthy controls were enrolled swabbed at three sites: back, antecubital fossa, shin. The severity subjects validated by Worst Itch Numeric...