A5113627968- Heart Rate Variability and Autonomic Control
- Nitric Oxide and Endothelin Effects
- Cardiovascular and exercise physiology
- Eicosanoids and Hypertension Pharmacology
- Traumatic Brain Injury and Neurovascular Disturbances
- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Cardiovascular Syncope and Autonomic Disorders
- Cardiac electrophysiology and arrhythmias
- Physical Education and Training Studies
- Physical Activity and Health
- Adipose Tissue and Metabolism
- Cardiac Arrhythmias and Treatments
- Blood Pressure and Hypertension Studies
- Vitamin K Research Studies
- Advanced Chemical Sensor Technologies
- Optical Imaging and Spectroscopy Techniques
- Vascular Anomalies and Treatments
- Neuroscience of respiration and sleep
Affiliated Hospital of Southwest Medical University
2025
University of Nebraska Medical Center
1988-2004
University of Nebraska at Omaha
1988-1991
BACKGROUND A carotid artery cavernous sinus fistula (CCF) is an abnormal shunt of blood vessels, allowing to flow directly or indirectly from the into sinus. The most common cause spontaneous CCF (s-CCF) ruptured internal carotid-cavernous aneurysms, while fibromuscular dysplasia (FMD) rare. FMD a rare, idiopathic, segmental, noninflammatory, and nonatherosclerotic disease medium-sized arteries, characterized by cell proliferation distortion arterial wall architecture. authors report case...
Prostaglandin (PG) I2 and PGE2 are known to stimulate left ventricular receptors with nonmyelinated vagal afferents. The present experiments were performed determine the effects of intracoronary infusion (10-50 ng.kg-1.min-1) arachidonic acid (50-100 micrograms.kg-1.min-1) on baroreflex control heart rate in conscious dogs. Dogs anesthetized pentobarbital sodium instrumented using sterile surgical techniques. After recovery, pressure-heart curves constructed by varying arterial pressure...
The present study was undertaken to determine whether left circumflex coronary artery (ic) administration of prostacyclin (PGI2) caused an inhibition the baroreflex control renal sympathetic nerve activity (RSNA). RSNA recorded in 12 dogs. Baroreflex sensitivity assessed by infusion either sodium nitroprusside or phenylephrine and determining slope mean arterial pressure-RSNA relationship. During infusion, intracoronary PGI2 depressed nearly 90% compared with tris(hydroxymethyl)aminomethane...
Prostaglandin I2 (PGI2) is known to stimulate ventricular C fiber receptors resulting in a Bezold-Jarisch-like reflex. Also, cardiac receptor stimulation interact with the expression of arterial baroreflexes. Therefore, experiments were performed determine effects left circumflex coronary artery infusion PGI2 on baroreflex control heart rate conscious instrumented dogs. Dogs chronically an aortic catheter for measurement mean pressure, hydraulic occluder cuffs descending aorta and inferior...
The role of the central nervous system in mechanism(s) involved acute carotid baroreflex resetting was studied six conscious, chronically instrumented, aortic-denervated dogs. Dogs were prepared for reversible vascular isolation sinuses. Acute induced by holding left sinus pressure (LCcsp) at a given value 20 minutes using pulsatile control while same time keeping right (RCSP) subthreshold level (approximately 40 mm Hg). At end minutes, LCcsp) reduced to approximately Hg, and (RCSP-mean...
Captopril administration has been shown to result in the release of prostaglandins (PGs) experimental animals and patients. Also, PGs, particularly prostacyclin (PGI2), have stimulate left ventricular receptor reflexes. Thus, hypothesis that captopril results sensitization reflexes via increased circulating levels PGs was tested conscious instrumented dogs. Left were stimulated by injecting veratridine into circumflex coronary artery through a nonocclusive catheter. Under control conditions,...
1. Acute baroreflex resetting in the control of arterial pressure was studied six chronically instrumented, conscious dogs. Following aortic baroreceptor denervation, carotid sinuses were surgically prepared for reversible vascular isolation. 2. During experiments both temporarily isolated from systemic circulation and conditioned with a pulsatile pressure. The sinus conditioning (CPCSP) at level 100, 140 or 60 mmHg 20 min each. Carotid (CSP) versus mean (MAP) curves constructed after each...