Comparative study of semi-quantitative value based on different reference point in diagnosis of pulmonary lesions with 18F-FDG coincidence imaging

• DOI: 10.3760/cma.j.issn.2095-2848.2013.06.007
• Publication Date: 2013-12-25
• Authors: Wu Lu; Peng Chen; Yong Liu; Changxiang Song; Peng Du
• Keywords: Cut-off

Objective To explore the optimal semi-quantitative uptake ratio for differentiation between benign and malignant lung lesions with 18F-FDG coincidence imaging.Methods One hundred thirty-seven patients (89 males,48 females,age range:33-78 years) diseases underwent 18 FFDG imaging.The maximum radioactivity counts of (T),normal chest wall soft tissues (NT1) contralateral tissue (NT2) were measured.The ratios R1 (T/NT1) R2(T/NT2) calculated.The threshold values R1(cutoff)and R2(cutoff) identified by ROC curve analysis.Using threshold,the sensitivity,specificity accuracy calculated.Results The as 3.58 4.40.The 90.0％(90/100),89.2％(33/37),89.8％(123/137) according to R1(cutoff) 90.0％ (90/100),78.4％(29/37),86.9％(119/137) Conclusion Based on which is taken a reference point,the value T/NT1 in imaging.

Key words: Lung neoplasms ; Coincidence Tomography, emission-computed, single-photon ; Tomography, X-ray computed; Deoxyglucose