Peng Chen

ORCID: 0009-0003-6912-9689
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Meningioma and schwannoma management
  • Advanced Fluorescence Microscopy Techniques
  • Advanced Electron Microscopy Techniques and Applications
  • ATP Synthase and ATPases Research
  • Head and Neck Surgical Oncology
  • Intracranial Aneurysms: Treatment and Complications
  • Sparse and Compressive Sensing Techniques
  • Sarcoma Diagnosis and Treatment
  • Bone Tumor Diagnosis and Treatments
  • Natural product bioactivities and synthesis
  • Mitochondrial Function and Pathology
  • Tumors and Oncological Cases
  • Biochemical and Structural Characterization
  • Medical Imaging Techniques and Applications
  • Mobile Ad Hoc Networks
  • Neurofibromatosis and Schwannoma Cases
  • Caching and Content Delivery
  • Cooperative Communication and Network Coding
  • Stochastic processes and statistical mechanics
  • Optical Imaging and Spectroscopy Techniques
  • Click Chemistry and Applications
  • Marine Sponges and Natural Products
  • Markov Chains and Monte Carlo Methods
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Biochemical Analysis and Sensing Techniques

Sichuan University
2025

Peking University
2013-2024

Kunming Medical University
2024

Georgia Institute of Technology
2024

Beijing Haidian Hospital
2023

Stomatology Hospital
2023

National Clinical Research Center for Digestive Diseases
2023

Xi'an Medical University
2020

The First People’s Hospital of Lianyungang
2013

Cornell University
2010

Capturing mitochondria's intricate and dynamic structure poses a daunting challenge for optical nanoscopy. Different labeling strategies have been demonstrated live-cell stimulated emission depletion (STED) microscopy of mitochondria, but orthogonal are yet to be established, image acquisition has suffered either from photodamage the organelles or rapid photobleaching. Therefore, nanoscopy mitochondria largely restricted two-dimensional (2D) single-color recordings cancer cells. Here, by...

10.1073/pnas.2215799119 article EN cc-by Proceedings of the National Academy of Sciences 2022-12-19

Bone defects caused by trauma or tumor led to high medical costs and poor life quality for patients. The exosomes, micro vesicles of 30-150 nm in diameter, derived from macrophages manipulated bone regeneration. However, the role hydrogen sulfide (H2S) biogenesis function exosomes its effects on regeneration remains elusive. In this study, we used H2S slow releasing donor GYY4137 stimulate found that promoted polarization M2 increase MSCs vitro vivo. Moreover, developed pre-treated...

10.1016/j.bioactmat.2023.08.006 article EN cc-by-nc-nd Bioactive Materials 2023-08-12

Maleimide-cysteine chemistry has been a routine practice for the site-specific labeling of fluorophores to proteins since 1950s. This approach, however, cannot bring out best photon budget fluorophores. Here, we systematically measured Cyanine3/5 dye conjugates via maleimide-thiol and amide linkages by counting total emitted photons at single-molecule level. While brightness signal-to-noise ratios do not change significantly, dyes with thioether exhibit more severe photobleaching than...

10.1021/jacs.2c12635 article EN Journal of the American Chemical Society 2023-02-09

Skin hemangioma is a tumor originating from skin blood vessels, which often occurs in infants and children. Brachytherapy with the 32P-based radionuclide applicator an effective non-invasive therapeutic method. However, inordinance of lesions still main challenge for precise local treatment radiation protection normal skins. A possessing advanced shape adaptability, favorable biodistribution, optimized stress feature, convenient preparation method highly required clinical practice. Herein,...

10.1039/d5tb00647c article EN Journal of Materials Chemistry B 2025-01-01

Fluorescence labeling of chemically fixed specimens, especially immunolabeling, plays a vital role in super-resolution imaging as it offers convenient way to visualize cellular structures like mitochondria or the distribution biomolecules with high detail. Despite development various distinct probes that enable super-resolved stimulated emission depletion (STED) live cells, most these membrane-potential-dependent fluorophores cannot be retained well after chemical fixation. This lack...

10.1073/pnas.2317703121 article EN cc-by Proceedings of the National Academy of Sciences 2024-04-30

Abstract OBJECTIVE AND IMPORTANCE: We present a case of patient with an ophthalmic artery aneurysm in which the originated from body aneurysm, requiring sacrifice to achieve complete obliteration. awakened intraoperatively assess optic nerve function after clipping and were able confirm function. Controlled intraoperative awakening proved valuable adjunct angiography determining immediate consequences artery. CLINICAL PRESENTATION: The was 55-year-old right-handed woman 3-month history...

10.1227/01.neu.0000156846.61123.79 article EN Operative Neurosurgery 2005-04-01

Data S1. Supporting info item Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by authors. Any queries (other than missing content) should be directed to corresponding author article.

10.1002/mrc.4567 article EN Magnetic Resonance in Chemistry 2016-12-15

.The calculation of the direction Wasserstein gradient is vital for addressing problems related to posterior sampling and scientific computing. To approximate using finite samples, it necessary solve a variation problem. Our study focuses on problem within framework two-layer networks with squared ReLU activations. We present semidefinite program (SDP) relaxation as solution, which can be viewed an approximation broader range functions, including networks. By solving convex SDP, we achieve...

10.1137/23m1573173 article EN SIAM Journal on Mathematics of Data Science 2024-10-10

Abstract Capturing mitochondria’s intricate and dynamic structure poses a daunting challenge for optical nanoscopy. Different labeling strategies have been demonstrated live-cell stimulated emission depletion (STED) microscopy of mitochondria, but orthogonal are yet to be established, image acquisition has suffered either from photodamage the organelles or rapid photobleaching. Therefore, nanoscopy mitochondria largely restricted 2D single-color recordings cancer cells. Here, by conjugation...

10.1101/2022.05.09.491019 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2022-05-09

In recent years, the focus to optimize network transmission efficiency has evolved adopt methods that let those intermediate data transferring nodes get involved with routing, forwarding and caching. other words, new architecture designs become in favor of hop-to-hop model, instead traditional TCP-like end-to-end model. Named networking is a promising future internet oriented which uses names addresses exchanges or forwards interest/data pair packets at each node along path route for...

10.1109/cse.2014.128 article EN 2014-12-01

Objective To explore the optimal semi-quantitative uptake ratio for differentiation between benign and malignant lung lesions with 18F-FDG coincidence imaging.Methods One hundred thirty-seven patients (89 males,48 females,age range:33-78 years) diseases underwent 18 FFDG imaging.The maximum radioactivity counts of (T),normal chest wall soft tissues (NT1) contralateral tissue (NT2) were measured.The ratios R1 (T/NT1) R2(T/NT2) calculated.The threshold values R1(cutoff)and R2(cutoff)...

10.3760/cma.j.issn.2095-2848.2013.06.007 article EN Zhonghua heyixue yu fenzi yingxiang zazhi 2013-12-25

The computation of Wasserstein gradient direction is essential for posterior sampling problems and scientific computing. approximation the with finite samples requires solving a variational problem. We study problem in family two-layer networks squared-ReLU activations, towards which we derive semi-definite programming (SDP) relaxation. This SDP can be viewed as an broader function including networks. By convex SDP, obtain optimal this class functions. Numerical experiments PDE-constrained...

10.48550/arxiv.2205.13098 preprint EN cc-by arXiv (Cornell University) 2022-01-01
Coming Soon ...