Radical operation on Tetralogy of Fallot and its perioperative outcomes in different ages

• DOI: 10.3760/cma.j.issn.2095-428x.2015.23.007
• Publication Date: 2015-12-05
• Authors: Lei Shi; Hongliang Xu; Jintao Zhang; Xinhua Wei
• Keywords: Ductus arteriosus; Extracorporeal circulation; Tetralogy

Objective To explore the feasibility and advantages of early open-heart radical operation on infants children with Tetralogy Fallot(TOF) in different ages to analyze its perioperative outcomes.

Methods The clinical data 390 TOF were analyzed, who underwent extracorporeal circulation surgery from January 2007 2014 at Department Cardiovascular Surgery, Third Affiliated Hospital Zhengzhou University.The operative age ranged 3 months 14 years(mean years). There 172 infants(<1 year old)and 218 children(≥1 old). Some accompanied abnormalities included atrial septal defect (33 cases), patent ductus arteriosus (17 coronary artery anomalies (8 multiple ventricular (5 cases).

Results Ten patients died, overall mortality during hospital stay was 2.56%.The group 2.32%(4/172 cases) 2.75%(6/218 respectively, there no significant difference(χ2=0.000, P=1.000). Extracorporeal time was(89.16±74.38) min (83.14±66.72)min, aortic clamping was(59.75±35.20) (54.70±38.54)min were(185.34±168.64)min (163.35±150.15) duration postoperative ventilation (57.17±67.46) h (47.50±58.39) h, hospitalization Intensive Care Unit (5.08±7.93) d (3.71±5.40) d, ave-raged (13.82±17.78) (9.52±8.74) respectively group; differences between 2 groups(t=1.937, 1.890, 1.991, 1.887, 1.951, 1.931; P=0.259, 0.713, 0.194, 0.739, 0.241, 0.308).

Conclusions The curative effect cardiac surgical treatment is considerably good low morbidity mortality.Early can avoid delayed development growth children, hypoxemic spells, sudden death some other kind adverse events.

Key words: Infant; Child; Tetralogy Fallot; Primary repair; Clinical result