Rapid identification of 14 bile acids contained in Qingkailing injection by HPLC-ESI-MS/MS

• DOI: 10.4268/cjcmm20130712
• Publication Date: 2013-06-20T07:56:40Z
• Authors: Jiayu Zhang; Qian Zhang; Hongxia Zhang; Luyan Dong; Jianqiu Lu; Yanjiang Qiao
• Keywords: Fragmentation

To investigate ESI-MS/MS fragmentation pattern of bile acids contained in Qingkailing injection, and the rapid identification method.HPLC-ESI-MS/MS technology was adopted to five rapidly identify injection from eight different manufacturers.5 showed similar patterns, based on which 14 were separated injection. Among them, 11 found injections all manufacturers, rest three individual manufacturers.HPLC-ESI-MS/MS is used complex material systems, provides an effective method for interpreting base compound traditional Chinese medicine preparations enhance quality standards.