A5029397332- Microbial Natural Products and Biosynthesis
- Plant Pathogens and Fungal Diseases
- Plant Disease Resistance and Genetics
- Microbial Metabolism and Applications
- Mycorrhizal Fungi and Plant Interactions
- Bacterial biofilms and quorum sensing
- Enzyme-mediated dye degradation
- Plant-based Medicinal Research
- Biochemical and Molecular Research
- Microbial Community Ecology and Physiology
- Semiconductor materials and devices
- RNA and protein synthesis mechanisms
- Silicon Nanostructures and Photoluminescence
- Plant-Microbe Interactions and Immunity
- Microbial Metabolic Engineering and Bioproduction
- Advances in Cucurbitaceae Research
- Fungal Biology and Applications
- Genomics and Phylogenetic Studies
- Click Chemistry and Applications
- CRISPR and Genetic Engineering
- Biochemical and Structural Characterization
- Plant Pathogens and Resistance
- Biosimilars and Bioanalytical Methods
- Chemical Synthesis and Analysis
- Genetic diversity and population structure
Chinese Academy of Sciences
1995-2021
North China University of Science and Technology
2019-2021
Microbiology Institute of Shaanxi
2017-2021
Institute of Microbiology
2016-2021
China University of Mining and Technology
2015
Ocean University of China
2011
Institute of Semiconductors
1995
Catalases play a key role in the defense against oxidative stress bacteria by catalyzing decomposition of H 2 O . In addition, catalases are also involved multiple cellular processes, such as cell development and differentiation, well metabolite production. However, little is known about abundance, diversity, distribution bacteria. this study, we systematically surveyed classified homologs three catalase families from 2,634 bacterial genomes. It was found that both typical Mn-catalase could...
Streptomycetes attract a lot of attention in metabolic engineering and synthetic biology because their well-known ability to produce secondary metabolites. However, the available constitutive promoters are rather limited this genus. In work, were selected from pool whose downstream genes maintained constant expression profiles various conditions. A total 941 qualified based on systematic analysis five sets time-series transcriptome microarray data Streptomyces coelicolor M145 cultivated...
Oxytetracycline (OTC) is a broad-spectrum antibiotic commercially produced by Streptomyces rimosus. Despite its importance, little known about the regulation of OTC biosynthesis, which hampered any effort to improve production via engineering regulatory genes.A gene encoding protein (SARP) was discovered immediately adjacent otrB oxy cluster in S. rimosus and designated otcR. Deletion complementation otcR abolished or restored production, respectively, indicating that encodes an essential...
Precise control of gene expression using exogenous factors is great significance. To develop ideal inducible systems for streptomycetes, new genetic parts, oxytetracycline responsive repressor OtrR, operator otrO, and promoter otrBp from Streptomyces rimosus, were selected de novo characterized in vivo vitro. OtrR showed strong affinity to otrO (KD = 1.7 × 10–10 M) induced dissociation the OtrR/DNA complex a concentration-dependent manner. On basis these synthetic system Potr* was optimized....