Laure Tonasso‐Calvière
A5051192800- Archaeology and ancient environmental studies
- Forensic and Genetic Research
- Genetic diversity and population structure
- Wildlife Ecology and Conservation
- Rangeland Management and Livestock Ecology
- Environmental DNA in Biodiversity Studies
- Forensic Anthropology and Bioarchaeology Studies
- Pleistocene-Era Hominins and Archaeology
- Identification and Quantification in Food
- Veterinary Equine Medical Research
- Metallurgy and Cultural Artifacts
- Archaeology and Natural History
- Genetic and phenotypic traits in livestock
- Molecular Biology Techniques and Applications
- Paleopathology and ancient diseases
- Ancient and Medieval Archaeology Studies
- Animal Diversity and Health Studies
- Genomics and Phylogenetic Studies
- Eurasian Exchange Networks
Centre National de la Recherche Scientifique
2022-2025
Université de Toulouse
2022-2025
Centre de Physiopathologie de Toulouse-Purpan
2024
Centre d'Anthropobiologie et de Génomique de Toulouse
2021-2024
Université Toulouse III - Paul Sabatier
2021-2024
AMIS - Laboratoire d'anthropologie moléculaire et imagerie de synthèse
2017-2020
Abstract Domestication of horses fundamentally transformed long-range mobility and warfare 1 . However, modern domesticated breeds do not descend from the earliest domestic horse lineage associated with archaeological evidence bridling, milking corralling 2–4 at Botai, Central Asia around 3500 bc 3 Other longstanding candidate regions for domestication, such as Iberia 5 Anatolia 6 , have also recently been challenged. Thus, genetic, geographic temporal origins remained unknown. Here we...
Donkeys transformed human history as essential beasts of burden for long-distance movement, especially across semi-arid and upland environments. They remain insufficiently studied despite globally expanding providing key support to low- middle-income communities. To elucidate their domestication history, we constructed a comprehensive genome panel 207 modern 31 ancient donkeys, well 15 wild equids. We found strong phylogeographic structure in donkeys that supports single Africa ~5000 BCE,...
The horse is central to many Indigenous cultures across the American Southwest and Great Plains. However, when how horses were first integrated into lifeways remain contentious, with extant models derived largely from colonial records. We conducted an interdisciplinary study of assemblage historic archaeological remains, integrating genomic, isotopic, radiocarbon, paleopathological evidence. Archaeological modern North show strong Iberian genetic affinities, later influx British sources, but...
Abstract Horses revolutionized human history with fast mobility 1 . However, the timeline between their domestication and widespread integration as a means of transport remains contentious 2–4 Here we assemble collection 475 ancient horse genomes to assess period when these animals were first reshaped by agency in Eurasia. We find that reproductive control modern domestic lineage emerged around 2200 bce , through close-kin mating shortened generation times. Reproductive following severe...
This paper reports a high-resolution isotopic study of medieval horse mobility, revealing their origins and in-life mobility both regionally internationally. The animals were found in an unusual cemetery site within the City Westminster, London, England. Enamel strontium, oxygen, carbon isotope analysis 15 individuals provides information about likely place birth, diet, during first approximately 5 years life. Results show that at least seven horses originated outside Britain relatively cold...
ABSTRACT In the last three decades, DNA sequencing of ancient animal osteological assemblages has become an important tool complementing standard archaeozoological approaches to reconstruct history domestication. However, key archaeological contexts are not always available or do necessarily preserve enough for a cost‐effective genetic analysis. Here, we develop in‐solution target‐enrichment approach, based on 80‐mer species‐specific RNA probes (ranging from 306 1686 per species)...
Climate affects habitat, food availability, and the movement sustainability of all life. In this work, we apply Indigenous Western scientific methods, including genomics isotope profiling, on fossils from across Beringia to explore effect climate change horses. We find that Late Pleistocene horses Alaska northern Yukon are related populations Eurasia crossed Bering land bridge multiple times during last glacial interval. also deeply divergent lineages north south American ice sheets...
Alongside horses, donkeys and their first-generation hybrids represent members of the Equidae family known for social, economic symbolic importance in protohistoric historical France. However, relative respective roles different regions time periods are difficult to assess based on textual, iconographic archaeological evidence. This is both due incomplete, partial scattered sources difficulties accurately assign fragmentary remains at proper taxonomic level. DNA-based methods, however, allow...
Age profiling of archaeological bone assemblages can inform on past animal management practices, but is limited by the fragmentary nature fossil record and lack universal skeletal markers for age. DNA methylation clocks offer new, albeit challenging, alternatives estimating age-at-death ancient individuals. Here, we take advantage availability a clock based 31,836 CpG sites dental age in horses to assess predictions 84 remains. We evaluate our approach using whole-genome sequencing data...
DNA hybridization-capture techniques allow researchers to focus their sequencing efforts on preselected genomic regions. This feature is especially useful when analysing ancient (aDNA) extracts, which are often dominated by exogenous environmental sources. Here, we assessed, for the first time, performance of hyRAD as an inexpensive and design-free alternative commercial capture protocols obtain authentic aDNA data from osseous remains. HyRAD relies double enzymatic restriction fresh...
While few places on earth have been as deeply impacted by the human-horse relationship steppes of Mongolia and eastern Eurasia, gaps in archaeological record made it strikingly difficult to trace when how first domestic horses were integrated into ancient societies this key region world. Recently, organic materials preserved melting mountain ice emerged a source insight region’s deep past. Newly-identified artefacts recovered from snow Altai Mountain range western (including metal artefacts,...
The field of ancient genomics has undergone a true revolution during the last decade. Input material, time requirements and processing costs have first limited number specimens amenable to genome sequencing. However, discovery that archaeological material such as petrosal bones can show increased DNA preservation rates, combined with advances in sequencing technologies, molecular methods for recovery degraded fragments bioinformatics, vastly expanded range samples compatible genome-wide...
Ancient DNA preservation in subfossil specimens provides a unique opportunity to retrieve genetic information from the past. As ancient extracts are generally dominated by molecules originating environmental microbes, capture techniques often used economically orthologous sequence data at population scale. Post-mortem damage, especially deamination of cytosine residues into uracils, also considerably inflates error rates unless treated with USER enzymatic mix prior library construction....
Abstract Domestic horses and donkeys played a key role in the initial colonization of Atlantic seaboard Americas, process partially chronicled by historical records. While Spanish colonists brought to Caribbean southern latitudes earlier, transport domestic English colony at Jamestown, Virginia 1606 was among first dispersals eastern seaboard. Archaeozoological analysis, isotope radiocarbon dating identifiable equid remains from two contexts associated with occupation Jamestown demonstrate...