A5020783823- Insect symbiosis and bacterial influences
- RNA Research and Splicing
- Mosquito-borne diseases and control
- Protein Structure and Dynamics
- Lipid metabolism and biosynthesis
- Physiological and biochemical adaptations
- Malaria Research and Control
- Viral Infections and Vectors
- Parasitic Diseases Research and Treatment
The University of Texas Southwestern Medical Center
2020-2021
Southwestern Medical Center
2020-2021
Baylor University
2016-2020
Diapause is a critical eco-physiological adaptation for winter survival in the West Nile Virus vector, Culex pipiens, but little known about molecular mechanisms that distinguish diapause from non-diapause this important mosquito species. We used Illumina RNA-seq to simultaneously identify and quantify relative transcript levels diapausing non-diapausing adult females. Among 65,623,095 read pairs, we identified 41 genes with significantly different abundances between these two groups....
Biomolecular condensates appear throughout the cell serving a wide variety of functions. Many to form by assembly multivalent molecules, which produce phase-separated networks with liquidlike properties. These then recruit client total composition providing functionality. Here we use model system poly-SUMO and poly-SIM proteins understand client-network interactions find that structure network plays strong role in defining recruitment thus The basic unit this is zipperlike filament composed...
Abstract The taxonomy of Culex pipiens complex mosquitoes is still debated, but in North America it generally regarded to include pipiens, molestus, and quinquefasciatus (or quinquefasciatus). Although these have very similar morphometry, they each unique life strategies specifically adapted their ecological niche. Differences the capability for overwintering diapause, bloodmeal preference, mating behaviors, reliance on blood meals produce eggs. Here, we used RNA-seq transcriptome analysis...
Biomolecular condensates appear throughout the cell serving a wide variety of functions. Many to form by assembly multivalent molecules, which produce phase separated networks with liquid-like properties. These then recruit client total composition providing functionality. Here we use model system poly-SUMO and poly-SIM proteins understand client-network interactions find that structure network plays strong role in defining recruitment, thus The basic unit this is zipper-like filament...