- Occupational exposure and asthma
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National Institute for Occupational Safety and Health
2005-2024
Centers for Disease Control and Prevention
1994-2024
American Conference of Governmental Industrial Hygienists
2011
United States Department of Health and Human Services
1995-2002
University of Cincinnati
1986-1988
Environmental Protection Agency
1984-1985
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTGas chromatographic/mass spectroscopy analysis of mutagenic extracts aqueous chlorinated humic acid. A comparison the byproducts to drinking water contaminantsW. Emile. Coleman, Jean W. Munch, William H. Kaylor, Robert P. Streicher, Paul. Ringhand, and John R. MeierCite this: Environ. Sci. Technol. 1984, 18, 9, 674–681Publication Date (Print):September 1, 1984Publication History Published online1 May 2002Published inissue 1 September...
To outline the knowledge gaps and research priorities identified by a broad base of stakeholders involved in planning participation an international conference agenda workshop on isocyanates human health held Potomac, Maryland, April 2013.A multimodal iterative approach was used for data collection including preconference surveys, review 2001 consensus isocyanates, oral poster presentations, focused break-out sessions, panel discussions, postconference workshop.Participants included...
In April 1991, an excess of bladder cancer cases among workers employed at a chemical manufacturing facility in Niagara Falls, NY, was reported. This primarily confined to 708 who had ever been the rubber chemicals area plant, where aromatic amines aniline and o -toluidine have historically used. An environmental biological monitoring survey conducted evaluate current exposures department. Personal air sampling for with use modified Occupational Safety Health Administration (OSHA) 73 method....
Background: Skin exposure to isocyanates, in addition respiratory exposures, may contribute sensitization and asthma. Quantitative skin data are scarce quantitative methods limited. Methods: As part of the Survey Painters Repairers Autobodies by Yale study, a method sample quantify human isocyanate was developed (based on NIOSH 5525 method) used evaluate aliphatic 81 auto body shop painters technicians. Wipe samples were collected from unprotected under PPE (gloves, clothing respirator)...
Chlorination of humic and fulvic acid results in the formation direct-acting mutagenicity, detectable Salmonella/microsome assay (Ames test). This mutagenicity is being characterized as part an overall effort aimed at evaluating potential health risks associated with presence mutagenic chemicals drinking water. A number chlorinated organic compounds, including several known mutagens, have been identified quantified diethyl ether extracts solutions. However, total these compounds accounts for...
Analytical reference standards generally are not available for non-monomeric isocyanate species, making accurate identification and quantitation by high-performance liquid chromatography (HPLC) difficult. A successful derivatizing reagent must react rapidly with all groups, the derivatized be detectable selectively at very low levels, detector used give a response proportional to number of groups present. novel reagent, 1-(9-anthracenylmethyl)piperazine (MAP), was prepared in an attempt...
Isocyanates may cause contact dermatitis, sensitization and asthma. Dermal exposure to aliphatic aromatic isocyanates can occur in various settings. The fate of on skin is an important unanswered question. Do they react bind the outer layer or do penetrate through epidermis as unreacted compounds? Knowing kinetics these processes developing dermal sampling decontamination strategies, well understanding potential health implications such have. In this paper residence time model hairless...
Tris(1-chloro-2-propyl) phosphate (TCPP, also referenced as TCIPP), a flame retardant used in spray polyurethane foam insulation, increases cell toxicity and affects fetal development. Spray workers have the potential to be exposed TCPP during application. In this study, we determined exposure concentrations of urinary biomarker bis(1-chloro-2-propyl) (BCPP) among 29 over 2 work days. Work was conducted at residential or commercial facilities using both open-cell (low density) closed-cell...
This paper evaluates the performance of NIOSH draft method 5525 for analysis monomeric and TRIG aliphatic isocyanates in autobody repair shops. It was found that an optimized pH gradient enhanced noticeably resolution and, therefore, identification isocyanates. Samples proved to be very stable at least a year when stored −13 °C freezer, no major stability problems were MAP reagent. The detector response factor RSD selected ureas 40% fluorescence (FLD), 3% UV 254 nm (UV254), 1% 370 (UV370)....
A comparison study of isocyanate sampling methods for 1,6-hexamethylene diisocyanate (HDI) monomer and HDI-based polyisocyanates was conducted in spray painting environments. This compared the performance Iso-chek sampler against existing proposed National Institute Occupational Safety Health (NIOSH) Administration (OSHA) monitoring isocyanates. Six HDI polyisocyanate levels were compared. Fifty-eight sets collected during aircraft parts at four U.S. Air Force bases. Impinger cassette...
Isocyanates may cause contact dermatitis and respiratory sensitization leading to asthma. Dermal exposure aliphatic isocyanates in auto body shops is very common. However, little known about the effectiveness of available commercial products used for decontaminating polyisocyanates. This experimental study evaluated decontamination polyisocyanates several skin surface decontaminants use industry. The efficiency two major mechanisms, namely (i) consumption free isocyanate groups via chemical...
The dry cleaning industry is moving away from using perchloroethylene. Occupational exposures to two alternative solvents, butylal and high-flashpoint hydrocarbons, have not been well characterized. We evaluated four shops that used these solvents. were staffed by Korean- Cantonese-speaking owners, Korean-, Cantonese-, Spanish-speaking employees. Because most workers had limited English proficiency we language services in our evaluations. In collected personal area air samples for butylal....
Results of a comparative field study on the performance 25-mm inhalable samplers (Institute Occupational Medicine [IOM]) and midget impingers for collection total isocyanates in air using 1-(9-anthracenylmethyl)piperazine (MAP) reagent are presented. Air sampling analysis was performed according to National Institute Safety Health MAP draft method 5525. Midget filled with 15 mL 1×10−4 M butyl benzoate were operated at 1 L/min. IOM cassettes loaded quartz fiber filters impregnated 500 µg MAP,...