A5101910383- Atrial Fibrillation Management and Outcomes
- Venous Thromboembolism Diagnosis and Management
- Advanced Malware Detection Techniques
- Software Engineering Research
- Cardiac Arrhythmias and Treatments
- Reproductive System and Pregnancy
- Antiplatelet Therapy and Cardiovascular Diseases
- Endometriosis Research and Treatment
- Surface Roughness and Optical Measurements
- Optical measurement and interference techniques
- Software Reliability and Analysis Research
- Acute Myeloid Leukemia Research
- Bayesian Modeling and Causal Inference
- Nerve injury and regeneration
- Neurogenesis and neuroplasticity mechanisms
- Atherosclerosis and Cardiovascular Diseases
- Chronic Myeloid Leukemia Treatments
- Anomaly Detection Techniques and Applications
- Domain Adaptation and Few-Shot Learning
- Axon Guidance and Neuronal Signaling
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Reproductive Physiology in Livestock
- Consumer Market Behavior and Pricing
- Acupuncture Treatment Research Studies
- Supply Chain and Inventory Management
Fujian Medical University
2021-2024
Yunnan University
2013-2024
Union Hospital
2021-2022
Zhejiang Chinese Medical University
2021
Kunming University of Science and Technology
2019
Zhejiang University
2016
Jiangsu University
2008-2015
Affiliated Hospital of Jiangsu University
2015
Neurons in the central nervous system (CNS) fail to regenerate axons after injuries due diminished intrinsic axon growth capacity of mature neurons and hostile extrinsic environment composed a milieu inhibitory factors. Recent studies revealed that targeting particular group extracellular factors is insufficient trigger long-distance regeneration. Instead antagonizing growing list impediments, tackling common target mediates inhibition offers an alternative strategy promote Neuronal cone,...
The aim of this study was to examine the interaction Notch/Notch ligand with Th17/Treg, cytokines IL-35 and IL-17 in cases preeclampsia (PE). Methods. Peripheral blood obtained from 42 PE patients 22 health pregnant women. mRNA expressions ligand, Treg transcription factor FoxP3 Th17 ROR γ t, EBI3 P35 (IL-35 two subunits), were determined by qPCR. serum levels measured ELISA. Results. It observed that Foxp3, EBI3, lower compared normal pregnancy, whereas t expression significantly increased....
The death-associated protein kinase 1 (DAPK1) gene is a candidate tumor suppressor (TSG) and the abnormal methylation of DAPK1 has been found in many carcinomas. epigenetic changes TSGs are now recognized as mechanism contributing to development chronic myeloid leukemia (CML). To clarify role CML, we examined status 49 patients with CML using methylation-specific polymerase chain reaction. aberrant was 25 (51.0%) cases, not all controls. No correlation between age, hematologic parameters,...
The aim of this study was to examine the interaction estradiol (E2) with CD4+CD25+FoxP3+ regulatory T (Treg) cells and cytokines in cases missed abortion (MA). peripheral blood lymphocytes from patients MA controls (normal pregnancy non-pregnant females) were isolated by Ficoll density gradient centrifugation. CD4+CD25+ Treg mononuclear (PBMCs). frequencies mRNA expression transcription factor forkhead box protein 3 (FoxP3) (n=33), normal (n=33) females (n=27) determined intracellular...
Promoter hypermethylation plays an important role in the inactivation of cancer-related genes. This abnormality occurs early leukemogenesis and seems to be associated with poor prognosis myelodsplastic syndrome (MDS). The identification more inactivated tumor suppressor genes contributing development MDS may lead further elucidation biology this disease help identify novel targets for therapy. In study, methylation status death-associated protein kinase 1 (DAPK1) gene promoter was analyzed...
In recent years, mobile medical technology has made great progress in chronic disease management, but its application patients with atrial fibrillation (AF) still needs to be clarified.
Depression is a global mental health problem with high disability rate, which brings huge disease burden to the world. Electroacupuncture (EA) has been shown be an effective method for treatment of depression. However, mechanism underling antidepressant effect EA not clearly clarified. The change synaptic plasticity focus in study mechanism. This will observe on LTP hippocampal and explore its possible mechanism.The depression-like behavior rat model was established by chronic unpredictable...
The principle of microscopic scattering dark-field imaging is adopted in surface defects evaluation system (SDES) for large fine optics. However, since are micron or submicron scale, cannot be described simply by geometrical imaging. In this paper, the simulation model electromagnetic field defect established on basis Finite-Difference Time-Domain (FDTD) method to study properties rectangular and triangular with different sizes simulation. criterion board scribed lines dots it used carry out...
The inspection of surface defects is one significant sections optical quality evaluation. Based on microscopic scattering dark-field imaging, sub-aperture scanning and stitching, the Surface Defects Evaluating System (SDES) can acquire full-aperture image elements then extract geometric size position information with processing such as feature recognization. However, distortion existing in SDES badly affects precision defects. In this paper, a correction algorithm based standard lattice...
Thalassemia is a serious hereditary disease, which cannot be cured. It's valuable to study on thalassemia. The input weights and biases of Extreme Learning Machine (ELM) can randomly initialized, sometimes get the better result. So new algorithm named SAELM based thalassemia proposed by using strong global optimization ability Simulated Annealing (SA) algorithm, find best ELM algorithm. Simulation results illustrated that than in main evaluation indices, so used as medical reference index screening
Introduction: Direct oral anticoagulants (DOACs) are associated with bleeding. Patients often stop taking DOACs due to nonmajor bleeding, which may lead venous thromboembolism (VTE) recurrence. We aimed determine the risk of bleeding using different prevent and treat VTE. Methods: PubMed, Embase, Web Science, Cochrane Library databases were searched from inception until January 6, 2021. The incidence clinically relevant minor was investigated. In frequentist-based network meta-analysis, we...
Software vulnerabilities detection is crucial in cyber security which protects the software systems from malicious attacks. The majority of earlier techniques relied on professionals to provide features before training a classification or regression model find vulnerabilities. However, defining and collecting high-quality labeled for are both time consuming. To handle these issues, this paper, we propose an unsupervised effective method extracting detecting automatically. Firstly, obtain...