Abstract Studies of strength development at polymer‐polymer interfaces are examined and applications to welding similar dissimilar polymers considered. The fracture properties the weld, namely, stress, σ, energy, G Ic , fatigue crack propagation rate da / dN microscopic aspects deformation process determined using compact tension, wedge cleavage, double cantilever beam healing experiments. mechanical related structure interface via mechanisms involving disentanglement bond rupture. time...

We demonstrate the first colloidal synthesis of single-crystalline BiOCl ultrathin nanosheets (UTNSs) that feature a well-defined square morphology. Unlike nanomaterials prepared by hydrothermal routes, our UTNSs exhibit hydrophobic surface properties and high activity selectivity toward photocatalytic aerobic oxidation secondary amines to corresponding imines at room temperature. Hence, application has been successfully extended from widely studied photodecomposition pollutants in aqueous...

BiVO4 was found to be an efficient photocatalyst under visible light irradiation for selective oxidation of amines imines with high activity (99% conversion) and selectivity (up 99%) using oxygen as oxidant.

An iron(II)-catalyzed diastereoselective olefin aminofluorination is reported (dr up to >20:1). This new transformation applies a functionalized hydroxylamine and Et3N·3HF as the nitrogen fluorine source, which facilitates efficient synthesis of β-fluoro primary amines amino acids from allylic alcohol derivatives. Preliminary mechanistic studies reveal that an iron–nitrenoid possible intermediate its reactivity enantioselectivity can be efficiently modulated by ligands.

Abstract Background As one of the major components lignocellulosic biomass, lignin has been considered as most abundant renewable aromatic feedstock in world. Comparing with thermal or catalytic strategies for degradation, biological conversion is a promising approach featuring mild conditions and diversity, received great attention nowadays. Results In this study, consortium white rot fungi composed Lenzites betulina Trametes versicolor was employed to enhance ligninolytic enzyme activity...

Contemporary Biocatalysis heavily relies on enzyme engineering as natural enzymes frequently lack the requisite attributes for effective organic synthesis. The inherent limitations in stability, catalytic activity, and selectivity of wild-type often hinder their suitability chemical Over past 25 years, there has been an unprecedented advancement protein tools, empowering enzymologists to customise precisely meet demands In this discussion, we delineate some most crucial techniques...

All roads lead to …︁ atropisomeric diaryl ethers containing a benzylic hydroxy group and an aldehyde unit. The isomers were synthesized in enantiomerically enriched form by desymmetrizing atroposelective enzymatic oxidation (with galactose oxidase (GOase) variant) or reduction ketoreductase (KRED); see scheme).

Peroxyzymes simply use H2O2 as a cosubstrate to oxidize broad range of inert C-H bonds. The lability many peroxyzymes against can be addressed by controlled supply H2O2, ideally in situ. Here, we report simple, robust, and water-soluble anthraquinone sulfonate (SAS) promising organophotocatalyst drive both haloperoxidase-catalyzed halogenation peroxygenase-catalyzed oxyfunctionalization reactions. Simple alcohols, methanol particular, used cosolvent an electron donor for generation. Very...

Light may participate in biocatalytic processes either by direct light-induced biocatalysis or cascading chemical reactions with ones, which are acknowledged as photocatalysis. As it combines the strength of chemocatalysis and biocatalysis, photobiocatalysis provides attractive advantages towards green synthesis terms atom efficiency, selectivity promiscuity. Particularly, has demonstrated its unique power C–H bond functionalization. Versatile approaches, mostly via combining photocatalytic...

Chern insulator (CI) exhibits rich physics with great interest in both theory and experiment. Here, we focus on the honeycomb kagome ferromagnets demonstrate that coupling nontrivial electronic magnonic bands allows for dual CIs, where quantum anomalous Hall effect its bosonic analogue, i.e., topological magnon insulator, appear simultaneously within one two-dimensional (2D) ferromagnet. Both tight-binding model Heisenberg-DM are constructed to feasibility of attaining CIs point out...

A novel NIR light responsive shape memory material exhibits excellent light-induced plasticity and multi-shape properties.

Atropisomeric biaryls carrying ortho-hydroxymethyl and formyl groups were made enantioselectively by desymmetrisation of dialdehyde or diol substrates. The oxidation the symmetrical substrates was achieved using a variant galactose oxidase (GOase), reduction dialdehydes panel ketoreductases. Either M P enantiomers products could be formed, with absolute configurations assigned time-dependent DFT calculations circular dichroism spectra. differing selectivities observed different biaryl...

Targeting the lysine residue of protein kinases to develop covalent inhibitors is an emerging hotspot. Herein, we have reported approach lysine-targeted PI3Kδ by in situ interaction upgradation H-bonding bonding. Several warhead groups were introduced and screened situ, leading bearing aromatic esters with high bioactivity selectivity. Compound A11 phenolic ester was finally optimized show a long duration action SU-DHL-6 cells multiple assays. Docking simulation further mass spectrometry...

Propargylic alcohols and amines are versatile building blocks in organic synthesis. We demonstrate a straightforward enzymatic cascade to synthesize enantiomerically pure propargylic from readily available racemic starting materials. In the first step, peroxygenase Agrocybe aegerita converted into corresponding ketones, which then were using (R)-selective alcohol dehydrogenase Lactobacillus kefir or (S)-selective Thermoanaerobacter brokii. Moreover, an Mitsunobu-type conversion of enriched...

Axially chiral aldehydes have emerged recently as a unique class of motifs for drug design. However, few biocatalytic strategies been reported to construct structurally diverse atropisomeric aldehydes. Herein, we describe the characterization alcohol dehydrogenases catalyze atroposelective desymmetrization biaryl dialdehydes. Investigations into interactions between substrate and key residues enzymes revealed distinct origin atroposelectivity. A panel 13 monoaldehydes was synthesized with...

A new furoketenimine intermediate from the coupling of ene-yne-ketones and o-alkenyl arylisocyanides, which enables efficient synthesis a wide range tetracyclic pentacyclic furan-fused heterocycles in one-pot domino process under catalyst-free conditions, is disclosed. Based on control experiments, cascade 1,6-addition, cyclization, intramolecular Diels–Alder reaction, oxidative aromatization was proposed for mechanism.

Highly enantioselective catalytic asymmetric intramolecular cascade imidization–nucleophilic addition–lactamization of N1-alkylethane-1,2-diamine with methyl 2-formylbenzoate catalyzed by a chiral phosphoric acid represents the first efficient method for preparation medicinally interesting 2,3-dihydro-1H-imidazo[2,1-a]isoindol-5(9bH)-ones high yields and excellent enantioselectivities. This strategy has been shown to be quite general toward various 2-formylbenzoates.