Nikita M. Paderin

ORCID: 0000-0001-5313-7105
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About
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Research Areas
  • Polysaccharides and Plant Cell Walls
  • Polysaccharides Composition and Applications
  • Proteins in Food Systems
  • Pickering emulsions and particle stabilization
  • Advanced Cellulose Research Studies
  • Seaweed-derived Bioactive Compounds
  • Hydrogels: synthesis, properties, applications
  • biodegradable polymer synthesis and properties
  • Phytochemistry and Bioactive Compounds
  • Stress Responses and Cortisol
  • Heart Rate Variability and Autonomic Control
  • Bone Tissue Engineering Materials
  • Wound Healing and Treatments
  • Diet and metabolism studies
  • Microbial Metabolites in Food Biotechnology
  • Advanced Drug Delivery Systems
  • Sleep and related disorders
  • Pharmacological Effects of Natural Compounds
  • Microencapsulation and Drying Processes
  • Silk-based biomaterials and applications
  • Gut microbiota and health
  • Nanocomposite Films for Food Packaging
  • Inflammation biomarkers and pathways
  • Obesity, Physical Activity, Diet
  • African Botany and Ecology Studies

Institute of Geology, Komi Science Centre
2008-2024

Ural Branch of the Russian Academy of Sciences
2020-2024

Russian Academy of Sciences
2007-2024

Czech Academy of Sciences, Institute of Physiology
2023-2024

Institute of Physiology, Komi Science Center
2021

The discrepancy between biological and social rhythms known as jetlag (SJL) is common in modern society has a range of negative consequences for cognitive functioning, well-being health. Social typical people with late chronotypes. As shown earlier, the prevalence individuals chronotype higher among residents high latitudes. Therefore, rate detection SJL should be expected North. In this study we assessed 62 young inhabitants European North Russia (the Komi Republic), relationship SJL,...

10.3109/07420528.2016.1168829 article EN Chronobiology International 2016-04-21

This study aimed to investigate the influence of kappa (κ)-carrageenan on initial stages foreign body response against pectin gel. Pectin-carrageenan (P-Car) gel beads were prepared from apple and κ-carrageenan using gelling with calcium ions. The inclusion 0.5% (Car0.5) in 1.5 (P1.5) 2% (P2) formulations decreased strength by 2.5 times. Car0.5 was found increase swelling P2 cell culture medium. adsorbed 30–42 mg/g bovine serum albumin (BSA) depending pH. P2-Car0.2, P2-Car0.5, P1.5-Car0.5...

10.3390/md20020094 article EN cc-by Marine Drugs 2022-01-22

The aim of the study was to develop ink enriched with a high content lupine callus tissue (CT) suitable for 3D printing. Printable obtained using mashed potatoes (20 g/100 mL) and 3% agar solution used as parent CT-free (CT0). Viscosity increased from 9.6 75.4 kPa·s during cooling CT0 50 20 °C, while viscosity 80 mL CT (CT80) 0.9 5.6 under same conditions. inclusion shown decrease hardness 3D-printed food gel 0.32 ± 0.03 0.21 N. storage modulus G' value 7.9 times lower in CT80 samples than...

10.3390/gels10010042 article EN cc-by Gels 2024-01-04

This study aims to develop hydrogels from apple pectin (AP) and hogweed (HP) in multiple ratios (4:0; 3:1; 2:2; 1:3; 0:4) using ionotropic gelling with calcium gluconate. Rheological textural analyses, electromyography, a sensory analysis, the digestibility of were determined. Increasing HP content mixed hydrogel increased its strength. The Young's modulus tangent after flow point values higher for than pure AP hydrogels, suggesting synergistic effect. chewing duration, number chews,...

10.3390/gels9030225 article EN cc-by Gels 2023-03-14

The study aims to develop gel beads with improved functional properties and biocompatibility from hogweed (HS) pectin. HS4 AP4 were prepared the HS pectin apple (AP) using gelling calcium ions. swelled in PBS dependence on pH. swelling degree of was 191 136%, respectively, at pH 7.4. hardness reduced 8.2 60 times, compared initial value after 24 h incubation. Both less Hanks' solution than containing peritoneal macrophages cell-free solution. Serum protein adsorption by 118 ± 44 196 68...

10.3390/ijms23063388 article EN International Journal of Molecular Sciences 2022-03-21

The study aimed to compare the in vitro biocompatibility of pectin gels formed by different cross-linking cations. Hydrogel beads named CaPG, ZnPG, FePG, and AlPG were prepared from 4% solutions apple using ionotropic gelling with CaCl2, ZnCl2, FeCl3, AlCl3, respectively. Cations influenced gel strength wet following order (least strong) Ca2+ < Zn2+ Fe3+~Al3+ (most strong). swelling degree CaPG after 24 h incubation RPMI-1640 medium was 104%, whereas swelled 76, 108, 134%, decreased...

10.3390/ijms232314789 article EN International Journal of Molecular Sciences 2022-11-26

The study aims to investigate the adhesion of a hydrogel made cross-linked low-methyl esterified pectin rat intestinal serosa ex vivo. adhesivity FeP hydrogel, which was by Fe3+ cations, exceeded that hydrogels Ca2+, Zn2+, and Al3+ cations. concentration cross-linking cation failed influence serosa. mechanical properties surface microrelief were influenced type cations form harder more elastic gel than Ca2+ Scanning electron microscopy analysis revealed characteristic pattern its denser...

10.3390/ijms24021248 article EN International Journal of Molecular Sciences 2023-01-08

In this work, we studied for the first time formation of olive oil emulsions in water stabilized by plate-like nanocrystals with supramolecular structure cellulose II (pCNC). Effects storage, pCNC concentration, and NaCl on stability properties Pickering emulsions, including creaming index, droplet size, zeta potential, acid-base surface properties, rheology, were studied. A significant influence shape nanoparticles (compared to classical rod-like shape) parameters rheological...

10.1021/acs.langmuir.3c01420 article EN Langmuir 2023-08-09

Abstract The pectic polysaccharide named potamogetonan (PN) was obtained using extraction of the leaves and stems common pondweed Potamogeton natans L. by an aqueous ammonium oxalate. purified PN‐300 membrane ultrafiltration PN proved to be pectin with a molecular weight 300 kDa. capacity prevent inflammation assessed carrageenan paw edema test in mice. Oral administration 24 h prior induction found reduce formation dose‐related manner. maximal effect observed at 1 after injection (60%...

10.1002/ptr.2125 article EN Phytotherapy Research 2007-03-14

Previous research has shown a high prevalence of late chronotype and social jetlag (SJL) among young northerners. These traits are also associated with unhealthy food preferences greater alcohol consumption. The aim this study was to analyze the relationships characteristics sleep–wake rhythm dietary residents North. involved 282 participants from Komi Republic (53.2% female) aged 18.9 ± 2.8 years old. Participants were asked provide personal data complete two questionnaires: Munich...

10.1080/09291016.2018.1455867 article EN Biological Rhythm Research 2018-03-25

The aims of the study were to evaluate influence pectin isolated from fireweed (FP) on mechanical and rheological properties agar (A) gel, investigate release phenolic compounds (PCs) A-FP gels at simulated digestion in vitro, oral processing sensory gels. hardness decreased gradually with increase concentration FP added (0.1, 0.4, 1.6%). A-FP1.6 gel was 41% lower than A gel. Rheological tests found a strong physical (storage modulus (G′) >>loss (G″)), addition up 1.6% did not significantly...

10.3390/gels8110708 article EN cc-by Gels 2022-11-02

The study aims to determine how chitosan impacts pectin hydrogel’s ability attach peritoneal leukocytes, activate complement, induce hemolysis, and adsorb blood proteins. hydrogels PEC-Chi0, PEC-Chi25, PEC-Chi50, PEC-Chi75 were prepared by placing a mixture solution of 4% in ratio 4:0, 3:1, 2:2, 1:3 1.0 M CaCl2. Chitosan was found modify the mechanical properties pectin–calcium hydrogels, such as hardness cohesiveness-to-adhesiveness ratio. hydrogel caused pH-sensitive swelling Hanks’...

10.3390/gels10070472 article EN cc-by Gels 2024-07-17

INTRODUCTION. One of the key stages wound healing is phase inflammation, which a transitional process between hemostasis and healing. Each stage inflammatory-reparative characterized by its own value acidity bed. For example, in acute medium bed decreases to pH 5.5-6. The chronic inflammatory process, on contrary, accompanied an increase 8. To date, so far, effect biomaterials containing components intercellular matrix human dermis fibroblasts under acidosis alkalosis has not been fully...

10.38025/2078-1962-2023-22-2-42-51 article EN cc-by Bulletin of Rehabilitation Medicine 2023-08-22

Vitamin D3 deficiency is a major public health problem worldwide, and standard cholecalciferol formulations provide poor absorbability of the vitamin. Several biphasic formulas have been proposed to overcome disadvantages in which Pickering emulsions stand out particular. This paper describes olive oil-in-water stabilized by pseudoboehmite (AlOOH), cellulose nanocrystals (CNC), their heterocoagulates. Colloidal properties were assessed laser Doppler microelectrophoresis, potentiometric...

10.1021/acsabm.2c00520 article EN ACS Applied Bio Materials 2022-08-26

In the present study, chitosan was included in pectin ionotropic gel to improve its mechanical and bioadhesive properties. Pectin-chitosan gels P-Ch0, P-Ch1, P-Ch2, P-Ch3 of weight fractions 0.00, 0.25, 0.50, 0.75 were prepared characterized by dynamic rheological tests, penetration serosal adhesion ex vivo assays. The storage modulus (G') loss (G″) values, hardness, elasticity P-Ch1 significantly higher than those P-Ch0 gel. However, a further increase content reduced these parameters....

10.3390/md21070375 article EN cc-by Marine Drugs 2023-06-25
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