Doxorubicin is an extensively prescribed antineoplastic agent. It also known for adverse effects, among which cardiotoxicity tops the list. The possible mechanism underlying doxorubicin (DOX)-mediated has been investigated in this study. Further, to reduce DOX-mediated cardiotoxicity, DOX was conjugated with Chitosan Nanoparticles (DCNPs) and supplemented propionic acid. Initially, drug loading efficacy conjugation of chitosan confirmed by UV-Visible Spectroscopy (UV) Fourier Transform...

Abstract Estimating pain levels is crucial for patients with serious illnesses, those recovering from brain surgery, and receiving intensive care etc. An automatic intensity estimator proposed in this study that gathers information about the user’s expressions. The faces database are first cropped using a ‘Chehra’ face detector, which performs well even wildly uncontrolled environments wide range of lighting position fluctuations. suggested technique extracts beneficial distinct patterns...

Diabetes is a complex disorder which requires constant attention to diet, exercise, glucose monitoring, and medication attain better glycemic control. The main goals of diabetes care are good metabolic control, minimization complications modified by patient compliance-the extent person's behavior coincides with medical or other health regimen. Poor adherence regimens common, contributing substantial deterioration disease, mortality increased health-care costs. Low treatments has resulted in...

Oestrus urine was proved as a potential endocrine modulator in alleviating the toxicity induced by 3-methylcholanthrene (3-MC) male rats. We, this study, aimed to prove attributing of alleviation squalene, an oestrus-specific pheromone A single dose (25 mg/kg BW, i.p.) administered Wistar rats with concurrent exposure squalene sprayed bedding material (Group III). Group II did receive 3-MC treatment but not expose squalene. I were intact control neither nor In consequence toxicity, liver and...

Abstract Worldwide, they are more than one in ten children born prematurely. Eleven countries, have higher preterm birth rates Premature maturation (born before 37 weeks of pregnancy) is strongly associated with difficulty breathing diseases, that is, the leading cause death for under five. Because their lungs well developed, enemies particular exposure to respiratory problems. One such child mortality worldwide Respiratory Distress Syndrome (RDS). Currently \ technology (recommended by WHO)...

Introduction: Diabetes Mellitus (DM) can be characterized as a metabolic disorder, which results in the increase of blood sugar level body might lead to macrovascular and microvascular complication. It is non- communicable disease. has also become major concern public health imposed an economic burden on society. Aim: The aim study assess knowledge, attitude practice Diabetic Retinopathy patients with south Indian population. Materials Methods: Patients who were diagnosed admitted...

BACKGROUND: Male breast cancer is a rare condition, accounting for less than 1% of all cancers, and infiltrating ductal carcinoma the most common type. However, Encapsulated Papillary Carcinoma (EPC) in males type cancer, exact etiology unknown. CASE REPORT: A 66-year-old male presented with 15x10 cm mobile swelling over left side anterior chest wall, which was clinically radiologically diagnosed as soft tissue tumor. Wide local excision wall performed. Grossly, it an encapsulated tumor...

Aim This study was intended to evaluate the knowledge and awareness towards infant oral health care among medical nursing undergraduates in Salem , Tamil Nadu. Material And Methods A conducted Salem. self administered 22 questionnaire regarding undergraduate students In this regard, a preliminary with convenience sample of 201 199 so as assess graduating Salem, Results had better compared students. Conclusion As nurses along professionals interact quite frequently parents children at very...

Introduction: There are comparatively fewer surgical site infections after craniofacial trauma than to the extremities, and etiology is complex. Gram-negative facultative anaerobic bacteria Veillonella a common commensal in oral cavity has been linked osteomyelitis prosthetic joint infections. They serve as early biological indicators. Aims/objectives: This study aims assess presence of patients presenting with maxillofacial trauma, document difference colony count requiring intervention at...

Background: Examining small bowel loops within the peritoneal cavity poses significant challenges because of their length and overlapping nature. Aims Objectives: This study aimed to evaluate utility computed tomography enteroclysis (CTE) in diagnosing intestinal diseases understand its clinical application. Materials Methods: The was conducted from November 2019 October 2021 30 patients undergoing CTE treatment. day before treatment, preparation included a low-residue diet, lots fluids, an...

<title>Abstract</title> Aim This study evaluated the effectiveness of transcutaneous electrical nerve stimulation (TENS) and interferential current therapy (IFT) to decrease jaw pain muscle tenderness, improve maximum vertical mouth opening, compare intra-operative patient comfort. Methodology: comparative was conducted in outpatient oral maxillofacial surgery department SRM Kattankulathur Dental College Hospital. Twenty participants with chronic or recurrent were randomly assigned either...

Objectives: Enterococcus faecalis is implicated in various human diseases, including urinary tract infections, dental conditions such as periodontitis, caries, systemic disorders infective endocarditis, meningitis, intra-abdominal and wound infections. The virulence genes associated with these diseases include adhesins ( ace, efaA, efaB, ebp ), biofilm-forming factors esp, gelE, fsr cytolysin cylA, cylB, cylM, cylL hyaluronidase hyl aggregation substance asp gelatinase gelE enterococcal...

Mosquitoes are the vectors of many severe diseases like malaria, dengue, yellow fever, filariasis, chikunguniya, west nile virus, western equine encephalitis and considered as one life threatening creatures in world. The present study aims to identify phytochemical compounds larvicidal activities two extracts, ethanol chloroform, leaves Muntingia calabura against filarial vector Culex quinquefasiatus compare efficiency these extracts. plant were collected, dried powdered extracts prepared...

Diabetes mellitus is a metabolic disorder that characterised by raised blood glucose level in the body as result of insulin resistance and pancreatic beta-cell failure defects secretion or action. Pharmacological therapy for management type II diabetes currently includes six classes Oral Antidiabetic drugs. They are Biguanides, Sulfonylureas, Meglitinides, Thiazolidinediones, Dipeptidyl peptidase IV inhibitors (DPP4) α-Glucosidase inhibitors. The five accessible DPP-4 sitagliptin,...

Background: Neonates are subjected to frequent painful procedures.Neonates can perceive pain which affect neurodevelopmental outcome.It is necessary assess and manage during various procedures.Objective: To compare the effect of oral 25% dextrose placebo in reducing neonatal after venepuncture.Methods: A randomised control study was done a tertiary care hospital.Neonates were into group using sterile water intervention dextrose.Two ml test solution administered neonate two minutes before...

The silver nanoparticles (Ag NPs) were derived from Acorus calamus (A. calamus) rhizome extract using different temperature. absorbance centered at 439 nm, which was corresponds to the wavelength of surface plasmon resonance Ag NPs 95 ◦C. From FESEM and TEM image showed, exhibited spherical structure. Elemental compositions identified by EDAX analysis. synthesized NPs, functional groups FTIR spectra. antibacterial studies performed against a set bacterial strains showed that possessed...