- Monoclonal and Polyclonal Antibodies Research
- Advanced Condensed Matter Physics
- Glycosylation and Glycoproteins Research
- Platelet Disorders and Treatments
- Complement system in diseases
- Blood groups and transfusion
- Inorganic Fluorides and Related Compounds
- Multiferroics and related materials
- Protein purification and stability
- Bacteriophages and microbial interactions
- Physics of Superconductivity and Magnetism
- Magnetic and transport properties of perovskites and related materials
- X-ray Diffraction in Crystallography
- Electronic and Structural Properties of Oxides
- Crystallization and Solubility Studies
- Scientific Computing and Data Management
- Food Allergy and Anaphylaxis Research
- Mesoporous Materials and Catalysis
- Mass Spectrometry Techniques and Applications
- Analytical Chemistry and Chromatography
- Zeolite Catalysis and Synthesis
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Advanced Biosensing Techniques and Applications
- Blood Coagulation and Thrombosis Mechanisms
- Magnetism in coordination complexes
University of Oxford
1993-2024
Trinity College Dublin
2021
Unilever (United Kingdom)
1997-2001
University of Michigan
1994
The layered honeycomb magnet alpha-RuCl3 has been proposed as a candidate to realize Kitaev spin model with strongly frustrated, bond-dependent, anisotropic interactions between spin-orbit entangled jeff=1/2 Ru4+ magnetic moments. Here we report detailed study of the three-dimensional crystal structure using x-ray diffraction on untwinned crystals combined structural relaxation calculations. We consider several models for stacking layers and find evidence monoclinic unit cell corresponding...
The layered honeycomb magnet $\ensuremath{\alpha}\text{\ensuremath{-}}{\mathrm{Li}}_{2}{\mathrm{IrO}}_{3}$ has been theoretically proposed as a candidate to display unconventional magnetic behaviour associated with Kitaev interactions between spin-orbit entangled ${j}_{\mathrm{eff}}=1/2$ moments on lattice. Here we report single crystal resonant x-ray diffraction combined powder neutron reveal an incommensurate order in the layers Ir counterrotating nearest-neighbor sites. This unexpected...
Thorough mixing of the starting materials is first step a crystal growth procedure. This holds true for almost any standard technique, whereas intentional separation educts considered to be restricted very limited number cases. A noticeable exception in gels that allows better control nucleation by limiting diffusion. The successful application this principle open systems, however, has remained elusive. Here we show single crystals {\alpha}-Li2IrO3 can grown from separated an crucible air....
Factor B is a five-domain 90 kDa serine protease proenzyme which part of the human serum complement system. It binds to other proteins C3b and properdin, activated by factor D. The fourth domain homologous type A von Willebrand (vWF-A). full-length cDNA clone was used amplify region encoding vWF-A (amino acids 229-444 B). fusion protein expression system then generate it in high yield Escherichia coli, where thrombin cleavage separate from its partner. second with improved stability...
Conference Article| February 01 1994 Binding sites involved in the formation of C3(H2O)-factor B complex alternative pathway complement SAMANTHA C. WILLIAMS; WILLIAMS 1MRC Immunochemistry Unit, Department Biochemistry, University Oxford, South Parks Road, Oxford OX1 3QU Search for other works by this author on: This Site PubMed Google Scholar ROBERT B. SIM Biochem Soc Trans (1994) 22 (1): 2S. https://doi.org/10.1042/bst022002s Views Icon Article contents Figures & tables Video Audio...
Abstract Factor B, a serine protease proenzyme and part of the complement system, binds to other proteins such as C3b properdin. While it is known be activated by factor D, interactions that interfere with binding between B are less well-understood. We attached thiol Sepharose via its free SH group conducted competition assay employing 125 I-labelled study competitive binding. Two anti-C3d monoclonal antibodies (F49b 4C2) were found partially inhibit C3b. The inhibitory effects these...
Conference Article| May 01 1997 Epitope mapping of bovine alpha-lactalbumin using a random phage display peptide library ALISON C. HUNT; HUNT 1Unilever Research, Colworth Laboratory, Sharnbrook, Bedford, MK44 1LQ Search for other works by this author on: This Site PubMed Google Scholar SAMANTHA WILLIAMS; WILLIAMS PAUL J. DAVIS; DAVIS R. ANDREW BADLEY Biochem Soc Trans (1997) 25 (2): 160S. https://doi.org/10.1042/bst025160s Views Icon Article contents Figures & tables Video Audio...