A5038153651- Parasitic infections in humans and animals
- Parasitic Infections and Diagnostics
- Congenital Anomalies and Fetal Surgery
- Parasite Biology and Host Interactions
- Toxoplasma gondii Research Studies
- Helminth infection and control
- Memory and Neural Mechanisms
- Parasites and Host Interactions
- Animal Ecology and Behavior Studies
- Neuroscience and Neuropharmacology Research
- Amoebic Infections and Treatments
- Neural dynamics and brain function
- Stress Responses and Cortisol
- Echinoderm biology and ecology
- Herpesvirus Infections and Treatments
- Chronic Disease Management Strategies
- Parasitic Diseases Research and Treatment
- Cell Image Analysis Techniques
- Coccidia and coccidiosis research
- Urological Disorders and Treatments
- Frailty in Older Adults
- Plant and fungal interactions
- Bacteriophages and microbial interactions
- Food Quality and Safety Studies
- Rabbits: Nutrition, Reproduction, Health
Northumbria University
2024-2025
University of Oxford
2024
University of Salford
2009-2023
COPE Galway
2023
QIMR Berghofer Medical Research Institute
2020
Administración Nacional de Laboratorios e Institutos de Salud
2020
University of Hohenheim
2020
University of Bern
2020
University of Minnesota
2014
Cambridge University Press
2013
Echinococcoses require the involvement of specialists from nearly all disciplines; standardization terminology used in field is thus crucial. To harmonize echinococcosis on sound scientific and linguistic grounds, World Association Echinococcosis launched a Formal Consensus process. Under coordination Steering Writing Group (SWG), Consultation Rating (CRG) had main missions (1) providing input list terms drafted by SWG, taking into account available literature participants' experience; (2)...
Transmission of auditory information from the medial geniculate body to lateral nucleus amygdala is believed be involved in conditioning fear responses acoustic stimuli. This pathway exhibits LTP electrically evoked field potentials after high frequency stimulation body. High also results a long-lasting potentiation potential elicited by naturally transduced stimulus. demonstrates that natural processing can make use physiological mechanisms set motion induction.
SUMMARY Three ELISA assays, based on hyperimmune rabbit serum raised against adult cestode somatic antigen, were applied in this study for the detection of Taenia - and Echinococcus -specific antigens host faeces. The first assay, using an antiserum pisiformis antigen extract, was used a time-course T. experimental infection dogs. assay shown to be considerably more sensitive than microscopical eggs Antigen present faeces before patency levels independent egg output. second involving test...
Echinococcosis is one of the world's most geographically widespread parasitic zoonoses, with transmission occurring in tropical, temperate and arctic biomes. Most human infections are due to Echinococcus granulosus transmitted between domestic dogs livestock, but this cosmopolitan species also cycles wild carnivores (principally canids) ungulates. The other significant zoonotic potential E. multilocularis that occurs naturally fox definitive hosts small mammal intermediate hosts. These two...
A prevalence study of abdominal cystic echinococcosis (CE) was undertaken in the northwest, north-central, and northeast regions Libya. total 36 villages along coast were included, which 20,220 people screened by portable ultrasound. Three hundred thirty-nine (1.7%) diagnosed with CE. There no significant difference between CE rates three Libya (mean = 1.6%); however, intervillage variable, ranging from 0% to 4.5%. The increased significantly age (P < 0.0001) females more affected (2%)...
SUMMARY Echinococcosis is a re-emerging zoonotic disease in Kyrgyzstan, and the incidence of human infection has increased substantially since collapse Soviet Union 1991. Domestic dogs are hosts Echinococcus spp. play an important role transmission these parasites. The demography, ecology behaviour therefore relevant studying transmission. Dog demographics, roles dogs, dog movements faecal environmental contamination were assessed four rural communities Alay Valley, southern Kyrgyzstan....
A prevalence and transmission study of human cystic echinococcosis (CE), due to infection with the dog tapeworm Echinococcus granulosus, was undertaken in village La Paloma central Uruguay. The population registered screened for CE by abdominal ultrasound scan as well a number serologic tests. Dogs were E. granulosus arecoline purgation specific coproantigen testing. total (new cases those previous history) 5.6% (64 1,149); 3.6% (40) new detected asymptomatic (mean age = 45 years). Age...
A rapid dot enzyme-linked immunosorbent assay (dot-ellsa) was developed as a field test for the diagnosis of cystic hydatid disease caused by Echinococcus granulosus. The 30 min based on detection antibodies to antigen B fluid and carried put using 50 μl whole blood in assessment Turkana region north-west Kenya. Initial laboratory studies showed be preferable crude cyst fluid, with 94% sensitivity 90·3% specificity infections. rapid, inexpensive simple perform is considered useful back-up...
Learned safety is established by negatively correlating the occurrence of a neutral stimulus and noxious stimulus, which renders previously 'safety signal'. While neurophysiological molecular mechanisms have been characterized in mice, it currently not known how neural substrates involved compare between mice people.Here we attempt to adapt original animal protocol humans use functional magnetic resonance imaging examine responses conditioned fear subjects. Diffusion tensor (DTI) was used...
SUMMARY The protozoan parasite Toxoplasma gondii is prevalent worldwide and can infect a remarkably wide range of hosts despite felids being the only definitive host. As cats play major role in transmission to secondary mammalian hosts, interaction between these should be factor determining final prevalence This study investigates T. natural population Apodemus sylvaticus collected from an area with low cat density (<2·5 cats/km 2 ). A surprisingly high 40·78% (95% CI: 34·07%–47·79%) was...
Rats treated with the AMPA receptor-facilitating drug 1-(quinoxolin-6-ylcarbonyl)piperidine (BDP-12) during training acquired fear conditioning to a tone faster than vehicle-treated controls. The effect on acquisition was dependent dose given. BDP-12-treated rats and controls reached same level of conditioned extinguished at rate. dissociation learning rate from these other normally covariant measures suggests that had specific isolated acquisition. Controls for effects stimulus sensitivity,...
In order to determine the prevalence of human cystic echinococcosis (CE) in semi-nomadic traditional pastoralist groups north-west China, 2 large community studies were undertaken Altai and Tacheng Prefectures 1990/91 1995/96, respectively. The Kekergash (Altai) comprised mainly ethnic Kazakhs, whereas Narenhebuke (Tacheng) Mongolians. Populations screened for CE by abdominal ultrasound scan (US) serological tests. total confirmed was higher (2·7%, 49/1844) than (0·9%, 17/1861; P < 0·01)....
Technology readinessThe SubtiToolKit (STK) technology standardizes the assembly of genetic constructs in Gram-positive bacteria, with potential for extension to Gram-negative species by building part libraries using STK syntax. This is ready be implemented as a tool accelerate modification thereby fostering advancements synthetic biology and its biotechnological applications. The designed use both basic applied research projects, including upstream bioproduction modify or adapt bacteria...
Selected cytokine profiles of lymphocytes were assessed in BALB/c mice infected with protoscoleces Echinococcus granulosus. Late stages the infection (three months+) characterized by more dominant Th2 activity elevated IL-4 and IL-10 reduced IFN-gamma output Con-A antigen stimulated splenocytes. Circumparasitic leucocytes produced mainly five months post infection. A peak production first month may suggest Th1 or Th0 at this time be correlated initial protoscolex death. In addition, from...
We analysed 3 independently collected datasets of fully censused helminth burdens in wood mice, Apodemus sylvaticus, testing the a priori hypothesis Behnke et al. (2005) that presence intestinal nematode Heligmosomoides polygyrus predisposes mice to carrying other species helminths. In Portugal, H. showed higher prevalence helminths but magnitude effect was seasonal. Egham, with species, not confounded by factors. Malham Tarn, were more likely be infected only among older mice. Allowing for...
Summary Acetylcholinesterase (AChE) secretion by adult N. americanus was enhanced in vitro incorporating insoluble collagen rafts into culture dishes. Enzyme produced this way had preferential substrate specificity for acetylthio‐choline iodide (ATC), and its activity inhibited cscrine (1.1 × 10 −8 m ). Ancylostoma ceytanicum , another hookworm species, failed to produce comparable amounts of AChE culture. efficiently purified from medium affinity chromatography on edrophonium sepharose; 81%...