A5015798114- Gastroesophageal reflux and treatments
- Child Nutrition and Feeding Issues
- Microscopic Colitis
- Celiac Disease Research and Management
- Diet and metabolism studies
- Eosinophilic Esophagitis
- Intestinal Malrotation and Obstruction Disorders
- Gastrointestinal motility and disorders
- Infant Health and Development
- Helicobacter pylori-related gastroenterology studies
- Clinical Nutrition and Gastroenterology
- Food Allergy and Anaphylaxis Research
- Esophageal and GI Pathology
- Diet, Metabolism, and Disease
- Gastrointestinal disorders and treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Intestinal and Peritoneal Adhesions
- Clostridium difficile and Clostridium perfringens research
- Inflammatory Bowel Disease
- Digestive system and related health
- Metabolism and Genetic Disorders
- Appendicitis Diagnosis and Management
- Infant Nutrition and Health
- Congenital Anomalies and Fetal Surgery
- Congenital gastrointestinal and neural anomalies
Emma Kinderziekenhuis
1990-2024
Vrije Universiteit Amsterdam
1999-2021
University of Amsterdam
1990-2021
Amsterdam University Medical Centers
2019-2021
Pediatrics and Genetics
2019
Amsterdam UMC Location Vrije Universiteit Amsterdam
2009-2018
Nederlandse Vereniging voor Kindergeneeskunde
1993-2015
Amsterdam UMC Location University of Amsterdam
2013
University Hospitals of North Midlands NHS Trust
2010
Keele University
2010
Disruption of the intestinal microbiota is considered an etiological factor in pediatric functional constipation. Scientifically based selection potential beneficial probiotic strains constipation therapy not feasible due to insufficient knowledge composition affected subjects. The aim this study was describe microbial and diversity children with constipation, compared healthy controls.Fecal samples from 76 diagnosed according Rome III criteria (median age 8.0 years; range 4.2-17.8) were...
Intestinal D-fructose absorption in 31 children was investigated using measurements of breath hydrogen. Twenty five had no abdominal symptoms and six functional bowel disorders. After ingestion fructose (2 g/kg bodyweight), 22 (71%) showed a hydrogen increase more than 10 ppm over basal values, indicating incomplete absorption: the averaged 53 ppm, range 12 to 250 ppm. Four these experienced symptoms. Three with disorders absorption. Seven were tested again an equal amount glucose, three...
Various surgical methods are used to treat meconium ileus (MI), including resection with enterostomy (RES), primary anastomosis (RPA), and purse-string enterotomy intra-operative lavage (PSI). The aim of this study is discuss the treatment MI, based on our experience. Of 41 MI patients treated at institution between 1984 2007, 18 had simple 23 complex MI. These groups were analyzed according modality, concentrating length hospital stay, complications [peritonitis, septicemia, adhesive small...
Infliximab is effective for induction and maintenance of remission in children with moderately to severely active Crohn's disease (CD).To evaluate the long-term efficacy infliximab treatment paediatric CD.In this observational, multicentre study, all CD patients The Netherlands treated from October 1992 November 2009 minimal follow-up 3 months since start infliximab, were studied.One hundred fifty-two [81M; median age at 15.0 years (IQR 13.1-16.4)] received a number 10.5 infusions 6-21)....
Summary Background Inflammatory bowel disease ( IBD ) affects a substantial number of female patients in their reproductive years. Therefore, many physicians face the dilemma whether thiopurines, prescribed to maintain remission, can be taken safely during pregnancy. Data on long‐term development outcome children exposed maternal thiopurine therapy are very limited. Aim To assess effects utero exposure thiopurines pregnancy infant health status. Methods A prospective multicentre follow‐up...
The aim of this study was to evaluate the current implementation 2009 North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition-European Nutrition guidelines, assess proton pump inhibitors' (PPIs) prescribing patterns among pediatricians from different European countries.A randomly identified sample general distributed across 11 countries. They were asked complete a case report-structured questionnaire investigating their approaches infants, children, adolescents with...
Background. Intestinal microbiome may play a role in the pathogenesis of coeliac disease (CD). Studies comparing intestinal children with and without CD are contradictory. Aim. To compare composition diversity duodenal mucosa-associated untreated control to identify specific gut bacteria associated at diagnosis. Methods. Total profile small bowel biopsies 42 (21 21 age-matched controls) were analyzed by means IS-pro, 16S-23S interspacer (IS) region-based profiling method. Results. Both...
Numerous diseases linked to microbial imbalance can be traced back childhood, illustrating the impact of juvenile microbiota development from infancy toward adulthood. However, knowledge on this subject is currently very limited. The primary aim study was characterize composition and short- long-term stability intestinal in healthy children. Between November 2011 June 2014, 61 children 2 18 yr age different areas Netherlands were included instructed collect fecal samples weekly, for 6 wk, a...
Intestinal microbiota is considered to play a crucial role in the aetiology of inflammatory bowel disease (IBD). We aimed describe faecal composition and dynamics large cohort children with de novo (naïve) IBD, comparison healthy paediatric controls (HC).In this prospective study, performed at two tertiary centres, samples from newly diagnosed, treatment-naïve IBD patients were collected prior cleansing for colonoscopy (t0) 1, 3 6 weeks months after initiation therapy. The microbial profiles...
Infliximab is effective for induction and maintenance of remission in Crohn's disease. It unknown how long patients should be kept on infliximab therapy. The primary aim this study was to assess duration therapy dependency pediatric CD initially responding therapy.All treated with by gastroenterologists the Netherlands because severe luminal or fistulizing initial response were reviewed. Duration therapy, clinical adverse events recorded.Sixty-six (37 boys) 10 hospitals Mean age at start...
Pathological food refusal (PFR) is not rare in young children with chronic conditions requiring prolonged tube feeding. We investigated whether these could be weaned from feeding a multidisciplinary hunger provocation program.The study included younger than 2 years PFR who had been dependent on for at least 3 months. They followed in-hospital program. During step 1, only 50% of the normal allowance was given by tube. 2, oral offered and completed up to afterwards. 3, supplementary night. 4,...