A5031660292- Clinical Nutrition and Gastroenterology
- Nutrition and Health in Aging
- Electrolyte and hormonal disorders
- Burn Injury Management and Outcomes
- Diet and metabolism studies
- Abdominal Surgery and Complications
- Vitamin C and Antioxidants Research
- Intensive Care Unit Cognitive Disorders
- Trace Elements in Health
- Wound Healing and Treatments
- Renal function and acid-base balance
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Respiratory Support and Mechanisms
- Cardiac Arrest and Resuscitation
- Injury Epidemiology and Prevention
- Metabolism and Genetic Disorders
- Disaster Response and Management
- Pharmacological Effects and Toxicity Studies
- Antibiotic Resistance in Bacteria
- Poisoning and overdose treatments
- Therapeutic Uses of Natural Elements
- Enhanced Recovery After Surgery
- Venous Thromboembolism Diagnosis and Management
- Hemodynamic Monitoring and Therapy
- Selenium in Biological Systems
University of Lausanne
2016-2025
University Hospital of Lausanne
2013-2024
Intensive Care Society
2002-2019
The First Affiliated Hospital, Sun Yat-sen University
2019
Zhongshan Hospital
2019
Fudan University
2019
Sun Yat-sen University
2019
Kantonsspital Winterthur
2018
University Hospital of Geneva
2018
Hôpital Orthopédique de la Suisse Romande
1998-2017
Critically ill patients have considerable oxidative stress. Glutamine and antioxidant supplementation may offer therapeutic benefit, although current data are conflicting.In this blinded 2-by-2 factorial trial, we randomly assigned 1223 critically adults in 40 intensive care units (ICUs) Canada, the United States, Europe who had multiorgan failure were receiving mechanical ventilation to receive supplements of glutamine, antioxidants, both, or placebo. Supplements started within 24 hours...
Gastrointestinal (GI) dysfunction is frequent in the critically ill but can be overlooked as a result of lack standardization diagnostic and therapeutic approaches. We aimed to develop research agenda for GI future research. systematically reviewed current knowledge on broad range subtopics from specific viewpoint dysfunction, highlighting remaining areas uncertainty suggesting studies.This systematic scoping review was conducted following successive steps: (1) identify clinically important...
BackgroundTrace elements and vitamins, named together micronutrients (MNs), are essential for human metabolism. The importance of MNs in common pathologies is recognized by recent research, with deficiencies significantly impacting the outcome.ObjectiveThis short version guideline aims to provide practical recommendations clinical practice.MethodsAn extensive search literature was conducted databases Medline, PubMed, Cochrane, Google Scholar, CINAHL initial guideline. focused on...
Objective: To evaluate the relative importance of increased lactate production as opposed to decreased utilization in hyperlactatemic patients, well their relation glucose metabolism. Design: Prospective observational study. Setting: Surgical intensive care unit a university hospital. Patients: Seven patients with severe sepsis or septic shock, seven cardiogenic and healthy volunteers. Interventions: 13C-labeled sodium was infused at 10 μmol/kg/min then 20 over 120 mins each. 2H-labeled...
Oxidative stress is involved in the development of secondary tissue damage and organ failure. Micronutrients contributing to antioxidant (AOX) defense exhibit low plasma levels during critical illness. The aim this study was investigate impact early AOX micronutrients on clinical outcome intensive care unit (ICU) patients with conditions characterized by oxidative stress.We conducted a prospective, randomized, double-blind, placebo-controlled, single-center trial admitted university hospital...
Critically ill patients are at high risk of malnutrition. Insufficient nutritional support still remains a widespread problem despite guidelines. The aim this study was to measure the clinical impact two-step interdisciplinary quality nutrition program.Prospective interventional over three periods (A, baseline; B and C, intervention periods).Mixed intensive care unit within university hospital.Five hundred seventy-two (age 59 ± 17 yrs) requiring >72 hrs treatment.Two-step program: 1)...