A5038727112- Mental Health Research Topics
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Functional Brain Connectivity Studies
- Neuroscience and Neuropharmacology Research
- Transcranial Magnetic Stimulation Studies
- Heart Rate Variability and Autonomic Control
- Neural and Behavioral Psychology Studies
- Advanced MRI Techniques and Applications
- Neural dynamics and brain function
- Vestibular and auditory disorders
- GABA and Rice Research
- Tryptophan and brain disorders
- Motor Control and Adaptation
Taipei Medical University
2019-2024
Taipei Medical University-Shuang Ho Hospital
2019-2021
Taipei Medical University Hospital
2021
National Central University
2021
University College London
2011-2012
Abstract The brain's intrinsic activity plays a fundamental role in its function. In normal conditions this is responsive to behavioural context, changing as an individual switches between directed tasks and task‐free conditions. A key feature of such changes the movement brain corresponding critical sub‐critical states, with these dynamics supporting efficient cognitive processing. Breakdowns processing efficiency can occur, however, disorders depression. It was therefore hypothesised that...
Rumination, a tendency to focus on negative self-related thoughts, is central symptom of depression. Studying the aspect such symptoms challenging because need distinguish self effects from emotional content task stimuli. This study employed an emotionally neutral paradigm investigate possible altered self-processing in depression and its link rumination.People with major depressive disorder (n = 25) controls underwent task-based electro-encephalogram recording. We studied late event-related...
Abstract The neurotransmitters GABA and glutamate have been suggested to play a role in Major Depressive Disorder (MDD) through an imbalance between cortical inhibition excitation. This effect has highlighted higher brain areas, such as the prefrontal cortex, but also posited basic sensory cortices. Based on this, magnetic resonance spectroscopy (MRS) was used investigate potential changes GABA+ glutamate+glutamine (Glx) concentrations within occipital cortex MDD patients (n = 25) healthy...
Abstract Rumination is a common symptom in major depressive disorder (MDD) and has been linked to risk for that disorder, its prognosis, relapse likelihood. Previous work individual differences rumination structural properties variety of brain regions. Some these regions, such as the dorsolateral prefrontal cortex (dlPFC), have also highlighted being altered MDD, suggesting connection between changes ruminative symptoms. Although informative, localised relations some limitations context...
Abstract The brain’s intrinsic activity plays a fundamental role in its function. In normal conditions this is responsive to behavioural context, changing as an individual switches between directed tasks and task-free conditions. A key feature of such changes the movement brain corresponding critical sub-critical states, with these dynamics supporting efficient cognitive processing. Breakdowns processing efficiency can occur, however, disorders depression. It was therefore hypothesised that...
Abstract Background Rumination, a tendency to focus on negative self-related thoughts, is central symptom of depression. Studying the aspect such symptoms challenging due need distinguish self effects per se from emotional content task stimuli. This study employs an emotionally neutral paradigm investigate possible altered processing in depression and its link rumination. Methods People with unipolar (MDD; n = 25) controls (n underwent task-based EEG recording. Late event-related potentials...