A5088061585- Hematopoietic Stem Cell Transplantation
- Lymphoma Diagnosis and Treatment
- Polyomavirus and related diseases
- Acute Myeloid Leukemia Research
- Hematological disorders and diagnostics
- Acute Lymphoblastic Leukemia research
- Chronic Lymphocytic Leukemia Research
- Viral-associated cancers and disorders
- Orthopedic Infections and Treatments
- Cytomegalovirus and herpesvirus research
- Immune Cell Function and Interaction
- Autoimmune and Inflammatory Disorders Research
- Head and Neck Anomalies
- Glioma Diagnosis and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Mast cells and histamine
- Skin and Cellular Biology Research
- Parvovirus B19 Infection Studies
- Mesenchymal stem cell research
- CNS Lymphoma Diagnosis and Treatment
- Neutropenia and Cancer Infections
- Blood groups and transfusion
- Respiratory Support and Mechanisms
- Iron Metabolism and Disorders
- Renal Transplantation Outcomes and Treatments
Hennepin County Medical Center
1990-2024
Hennepin Healthcare Research Institute
2023-2024
University of Minnesota
1994-2023
University of Minnesota Medical Center
2005-2023
Saint Louis University
2005
Twin Cities Orthopedics
2000
University of Utah
1986
Background and Objectives Acquired red cell aplasia (RCA) is a rare disorder can be either idiopathic or associated with certain diseases, pregnancy, drugs. In exceptionally cases, it has been reported to co-exist other autoimmune cytopenias. We report high incidence of RCA hemolytic anemia (AIHA) in pancreas transplant recipients on alemtuzumab-based maintenance therapy.Design Methods Between February 2003 July 2005, 357 were treated immunosuppressive regimens containing the...
Double- and triple-hit lymphomas (DHL/THL) are aggressive B-cell neoplasms characterized by translocation of MYC with concurrent BCL2 and/or BCL6 translocation. In this retrospective study from one institution, we report clinicopathologic features 13 cases (9 DHL/4 THL). The median age was 59 years (range 30-74) patients included eight females five males. Presentation enlarging lymphadenopathy/masses (11 patients) abnormal peripheral blood findings (2 patients). Features which raised the...
Journal Article Morphologic and Quantitative Changes in Blood Marrow Cells Following Growth Factor Therapy Get access Laura L. Schmitz, MD, MD 1From the Department of Pathology, University Minnesota School Medicine, Minneapolis, Minnesota. Search for other works by this author on: Oxford Academic Google Scholar John S. McClure, Craig E. Litz, Vanessa Dayton, Daniel J. Weisdorf, 2Department Internal Janet Parkin, MT, MT Richard D. Brunning, American Clinical Volume 101, Issue 1, 1 January...
Early after umbilical cord blood transplantation, patients show marked differences in bone marrow (BM) hematogone percentages. Little is known about whether these are clinically relevant. We hypothesized that early recovery of hematogones may be associated with improved transplantation outcomes. BM aspirates were assessed from 88 acute myeloid leukemia by two independent reviewers at day 21 and 100 transplantation. Interobserver variability for percentages time points showed correlation...
The term cutaneous pseudolymphoma (CPL), an accumulation of lymphocytes in response to a foreign antigen or unknown stimuli lacks specificity, and has been used when neither cause nor mechanism for the lymphocytic proliferation identified. Cases childhood CPL are rare require extensive investigation because their potential malignant transformation. We report case child with scalp mass diagnosed as CPL.
We evaluate the need for, feasibility of, and impediments to improving hematopathology diagnoses for cancer hospitals in Vietnam.Two hematopathologists from United States visited three major treatment Vietnam workshop a sampling of difficult cases. With Vietnamese pathologists, they toured histopathology, immunohistochemistry, ancillary laboratory facilities.Automated tissue processors slide staining equipment were documented each hospitals. Between seven 11 cases reviewed hospital....
Although current therapies for acute promyelocytic leukemia (APL), such as all- trans retinoic acid and arsenic trioxide, usually result in remission, some patients relapse. Early recognition of relapse is critical prompt intervention. In this study, we systematically reviewed morphologic, immunophenotypic, cytogenetic findings paired diagnostic relapsed APL cases describe quantify the changes blast morphology at relapse.By electronic database search, identified eight which peripheral blood...
Abstract Hemorrhagic cystitis is a common complication following the use of cyclophosphamide. Associated dysuria can be painful and there are few good options to relieve pain. Phenazopyridine has historically been utilized for available over counter. However, it associated with hematologic side effects prolonged use. Here we present case patient who developed Heinz body hemolysis administration phenazopyridine treat cyclophosphamide‐induced hemorrhagic hematopoietic stem cell transplant.
Abstract Objectives Leukemia diagnosis in Vietnam is limited by a lack of hematopathology training and expert consultation as well the cost high-magnification digitization hematology slides. Screen-sharing software allows international collaboration with experienced hematopathologists for improved diagnostic accuracy. Methods A education program was proposed hospitals. By appointment, pathologists access to microscope camera, imaging software, high-speed internet were invited review slides...
Abstract The purposes of this study were to determine (1) the effects positive end‐expiratory pressure (PEEP) and lung volume on systemic blood flow, (2) whether PEEP levels yielding maximum oxygen transport are associated with compliance, (3) pulmonary resistance gas in an animal model respiratory distress. Twelve cats inoculated 12 mg/kg N‐Nitroso N‐Methylurethane (NNNMU) induce NNNMU caused a 76% decrease disaturated phosphatidyl‐choline lavage, 34% functional residual capacity (FRC), 80%...
The treatment of Burkitt lymphoma (BL) has come a long way in regards to survival, with the majority even advanced stage patients being cured. prognosis for relapsed BL remains dismal, despite attempts further intensify therapy. We report on patient who CNS while was successfully treated an intensified regimen based concentration times time (C x T) CNS-directed model. Our experience shows both feasibility and efficacy such approach otherwise very poor prognosis.
Introduction: Double-hit lymphoma (DHL) and triple-hit (THL) are morphologically heterogeneous B cell neoplasms characterized by rearrangement of the MYC proto-oncogene with concurrent BCL2 and/or BCL6 gene rearrangement, as detected fluorescence in situ hybridization (FISH) or conventional cytogenetic analysis (G-banding). DHL THL aggressive lymphomas poor survival rates. Classification according to 2008 World Health Organization criteria can be challenging, most cases …
Abstract Background: Aggressive NK cell leukemia (ANKL) and systemic EBV-positive T-cell lymphoma of childhood (SEBVTCL) with CD4-positive immunophenotype are both rare. Both entities associated prior chronic active EBV disease (CAEBV) presentation Hemophagocytic Lymphohistiocytosis (HLH). Whereas ANKL is typically seen in young to middle-aged adults, SEBVTCL most commonly children adults. We report the case a 30-year-old Vietnamese woman who presented acutely high fever, generalized...
Abstract Background Using the World Health Organization Classification 5th edition (beta version online; WHO-HAEM5bv) in emerging economies is key to global healthcare equity. Although there may be ongoing updates, hesitancy accepting and reporting these diagnoses publication conflicts with WHO’s commitment accessibility. Aggressive NK cell leukemia (ANKL) systemic EBV-positive T-cell lymphoma of childhood (SEBVTCL) CD4-positive immunophenotype are both rare entities, most described Asians...
Fraser, Christopher J1; Hirsch, Betsy A2; Dayton, Vanessa2; Neglia, Joseph P1; Wagner, John E1; Baker, K Scott1 Author Information