A5074912889- Nanoparticles: synthesis and applications
- Nanoparticle-Based Drug Delivery
- Graphene and Nanomaterials Applications
- Nanoplatforms for cancer theranostics
- Computational Drug Discovery Methods
- Alzheimer's disease research and treatments
- Carbon and Quantum Dots Applications
- Advanced Nanomaterials in Catalysis
- Extraction and Separation Processes
- RNA modifications and cancer
- Cholinesterase and Neurodegenerative Diseases
- COVID-19 Clinical Research Studies
- Metal complexes synthesis and properties
- Radioactive element chemistry and processing
- Aortic aneurysm repair treatments
- Essential Oils and Antimicrobial Activity
- Barrier Structure and Function Studies
- Recycling and Waste Management Techniques
- Central Venous Catheters and Hemodialysis
- Advanced Drug Delivery Systems
- Analytical chemistry methods development
- Advancements in Transdermal Drug Delivery
- Poxvirus research and outbreaks
- Polymer Nanocomposite Synthesis and Irradiation
- Protein Structure and Dynamics
Wayne State University
2020-2025
The Barbara Ann Karmanos Cancer Institute
2020-2025
University of Miami
2021-2024
University of Michigan
2024
Michigan United
2024
Henan University
2019-2024
Eugene Applebaum College of Pharmacy and Health Sciences
2020-2023
Michigan Medicine
2023
King Abdulaziz University
2021
Aligarh Muslim University
2015-2020
Due to drug addiction and the emergence of antibiotic resistance in pathogens, disease load medication intake have risen worldwide. The alternative treatment for drug-resistant infections is Nano formulation-based antimicrobial agents. plant extract Conocarpus Lancifolius fruits was used synthesize silver nanoparticles current study, it further employed as an anticancer agent. Nanoparticles been characterized by UV-visible spectrometer revealed notable peak λ
Biomimetic synthesis of ZnO–NPs and their topical application on <italic>S. aureus</italic> induced skin infection leads to reduction in mice model.
Docking of various therapeutically important chemical entities to the specific target sites offers a meaningful strategy that may have tremendous scope in drug design process. For thorough understanding structural features determine strength bonding between ligand with its receptor, an insight visualize binding geometries and interaction is mandatory. Bioinformatical as well graphical software ‘PyMOL’ combination molecular docking suites Autodock Vina allows study understand...
The zinc oxide nanomaterials (ZnO-NMs), owing to their broad biomedical applications have lately attracted the incredible interest in development of therapeutic agents against microbial infections. In this contribution, we biosynthesized ZnO-NMs with a size ˜ 40 nm from Bougainvillea flower extracts. FTIR and SEM-EDX mapping analysis confirmed size, shape biogenic origin ZnO-NPs. Furthermore, purified were applied for antibacterial studies susceptible resistant bacterial strains elucidate...
Considering the significance of biological and eco-friendly nanomaterials, in present study, we have synthesized silver nanoparticles from exopolysaccharide recently recovered bacterial strain CEES51 Red Sea coastal area Jeddah, Saudi Arabia. 16S ribosomal RNA gene sequencing was used to characterize isolated bacteria, it identified as Mesoflavibacter zeaxanthinifaciens assigned an accession number MH707257.1 GenBank. The is excellent producer survived at hypersaline (30%) high-temperature...
In this research, Bougainvillea glabra paper flower extract was used to quickly synthesize biogenic silver nanoparticles (BAgNPs) utilizing green chemistry. Using the as a biological reducing agent, were generated by conversion of Ag+ cations Ag0 ions. Data patterns obtained from physical techniques for characterizing BAgNPs, employing UV-visible, scattering electron microscope (SEM), transmission (TEM), dynamic light (DLS), X-ray diffraction (XRD), and Fourier-transform infrared...
Abstract Diabetes significantly impairs the body's wound‐healing capabilities, leading to chronic, infection‐prone wounds. These wounds are characterized by hyperglycemia, inflammation, hypoxia, variable pH levels, increased matrix metalloproteinase activity, oxidative stress, and bacterial colonization. complex conditions complicate effective wound management, prompting development of advanced diabetic care strategies that exploit specific characteristics such as acidic pH, high glucose...
Biomimetic synthesis of nanoparticles offers a convenient and bio friendly approach to fabricate complex structures with sub-nanometer precision from simple precursor components. In the present study, we have synthesized Amphotericin B (AmB), potent antifungal agent, using Aloe vera leaf extract. The AmB nano-assemblies (AmB-NAs) was established employing spectro-photometric electron microscopic studies, while their crystalline nature by X-ray diffraction. AmB-nano-formulation showed much...
Sometimes, life-threatening infections are initiated by the biofilm formation facilitated at infection site drug-resistant bacteria Staphylococcus aureus. The aggregation of same type leads to on delicate tissue, dental plaque, and skin. In present investigation, a Graphene (Gr)-based nano-formulation containing Curcumin (C.C.M.) Zinc oxide nanoparticles (ZnO-NPs) showed wide range anti-microbial activity against Methicillin-resistant aureus (MRSA) demonstrated mechanism action. effect GrZnO...
The constant rise of microbial biofilm formation and drug resistance to existing antimicrobial drugs poses a significant threat community health around the world because it reduces efficacy efficiency treatments, increasing morbidity, mortality, health-care expenditures. As result, there is an urgent need develop novel agents that inhibit formation.The [Ni0.4Cu0.2Zn0.4](Fe2-xDyx)O4(x≤0.04) (Ni-Cu-Zn) nano spinel ferrites (NSFs) have been synthesized by sol-gel auto-combustion process were...
Nowadays, the infection caused by methicillin-resistant Staphylococcus aureus (MRSA) and countless different types of bacterial cause death millions people worldwide. Thereby, several strategies have explored for advancement better active antimicrobial agents; one these lies in form two-dimensional carbon-based nanocomposites. Herein, we demonstrate synthesis graphene-polyindole (Gr@PIn) nanocomposite polyindole (PIn) significantly enhance proficiency against MRSA strains which are immune to...
The ongoing outbreak of coronavirus disease COVID-19 is significantly implicated by global heterogeneity in the genome organization severe acute respiratory syndrome 2 (SARS-CoV-2). causative agents whole SARS-CoV-2 are not well characterized due to lack comparative study a large enough sample size from around globe reduce standard deviation acceptable margin error. To better understand architecture, we have performed comprehensive analysis codon usage bias sixty (60) strains get snapshot...
The molecular transformation of the human preaccess vein after arteriovenous fistula (AVF) creation is poorly understood. This limits our ability to design efficacious therapies improve maturation outcomes.
A 40-year-old man presented with obstructive jaundice complicated by DIC and AKI, highlighting the challenges in diagnosis management. Obstructive can present a spectrum of complications, including which significantly impact patient management outcomes. Prompt recognition intervention are crucial such cases. ERCP stent placement is an effective therapeutic modality for relieving biliary obstruction. Close monitoring multidisciplinary involving hepatologists, nephrologists, intensivists...