Background. In patients with injuries of large joints, the activation inflammation causes risk thrombophilia. The prediction thrombotic complications and their prevention can improve quality treatment. purpose: to investigate data scientific medical literature on pathogenetic association between markers hemostasis in degenerative diseases post-traumatic joints. Materials methods. search for has been made PubMed database 10 years. Sixty works were selected. Results. A total 60 papers selected...

The Forgotten Joint Score-12 (FJS-12) is an important tool for assessing the effectiveness of treatment patients after large joint arthroplasty. Its main advantage its sensitivity to patient's subjective perception artificial joint, which makes it extremely useful level comfort surgery. Objective. To perform official translation scale into Ukrainian, conduct adaptation and validation among who have undergone knee or hip was carried out within framework cooperation with Scores (BGGK GmbH,...

Background: There is a lack of comparative data on osseointegration (BIC) acetabular cup surfaces in hip arthroplasty both normal bone mineral density and conditions osteoporosis. Aim: To compare implants with various types an animal model osteoporotic tissue. Material Methods: The study was performed 60 rats. simulate osteoporosis ovariectomy 30 animals. Thirty healthy rats served as controls. In standardised defects the distal metadiaphysis femur we implanted: porous tantalum Trabecular...

Total hip arthroplasty is a common surgical treatment for elderly patients with osteoporosis, particularly in postmenopausal women. In such cases, highly porous acetabular components are favorable option achieving osseointegration. However, further discussion needed if use of justified under the condition normal bone mass.To determine features osseointegration two different types titanium implants [3-dimensional (3D)-printed and plasma-coated implants] tissue distal metaphysis rat femur...

Predicting the risk of developing thrombotic complications is an extremely important task when planning total arthroplasty large joints (TAJ). Objective. Based on retrospective analysis results biochemical examination patients with degenerative diseases before and after TAJ, determine changes in markers hemostasis system inflammatory processes, which are most informative for preoperative prediction development hypercoagulable conditions. Methods. In blood serum 39 hip knee III–IV stages...

Recently for improving techniques of operations in orthopedics and traumatology they widely used mathematical modeling. Need this presented work is due to the lack studies stress-strain state (SSS) pelvic bones terms modeling whole ring. Objective: using study impact SSS on separate parts pelvis. Methods: A geometric model pelvis was developed at biomechanical laboratory SI «Sytenko Institute Spine Joint Pathology National Academy Medical Science Ukraine», Kharkivbased creating models by...

Мета: на основі ретроспективного аналізу історій хвороби, рентгенограм та комп’ютерних томограм з метою профілактики визначити основні причинні фактори виникнення вивихів головки ендопротеза у пацієнтів після первинного ендопротезування кульшового суглоба. Матеріали методи. Історії хвороб, рентгенометрія аналіз 48 вивихом ендопротеза. Результати. Після операцій суглоба, що були виконані в період 2000 по 2015 рік (загалом 3886 операцій), вивихи виявлені (1,23 %), які лікувалися Інституті...

Fixing the acetabular component of prosthesis in conditions osteoporosis and changes acetabulum anatomy is an actual problem modern orthopedics.The goal: to perform a comparative analysis strength bone-metal block for different type implant surfaces ofnormal bone simulation rats.The methods: experimental studies femur were carried 60 laboratory animals (rats). The divided into two groups 30 each: I — relatively healthy, II induced by ovariectomy. 6 subgroups formed each group animals....

The article presents results of hip joint arthroplasty for two periods: I – 1968–1994 and II 1995–2005 (2,798 operations). basic types complications, which required repeated surgical interferences, are analysed. Three groups factors, influenced the development above formulated. observance suggested methods prophylaxis enabled authors, during remote postoperative period, to improve good from 73 % 89 decrease unsatisfactory ones 10 3 %.

Status of development and outlooks joint replacement procedures in Ukraine were analyzed. It is noted that under the auspices Ministry Health, National Academy Medical Sciences, Association Orthopaedic Surgeons Traumatologists there established actively deal some regional centers Kiev, Kharkov, Dnepropetrovsk, Donetsk as well city equipped with modern kinds endoprostheses instruments. There are qualified surgeons experienced on replacement, anesthesiologists rehabilitation specialists...

Objective: To conduct a retrospective analysis of radiographs and CT scans for studying typical changes in acetabulum (A) proximal femur (F) patients with the consequences injuries area hip joint.Methods: We analyzed 106 patients. Patients were divided into groups: I — false joint F neck, II – at level per-, inter- subtrochanteric F, III post-traumatic avascular necrosis head, IV posttraumatic coxarthrosis, V inveterate fracture dislocation. performed an assessment condition space endplates,...

Osseointegration of porous titanium and tantalum implants in ovariectomized rabbits: A biomechanical study

Hip and knee joints replacement became widespread in the world Ukraine due to their high efficiency improvement of life quality. However, similar any other surgical intervention, it is not without complications. Periprosthetic infection among most difficult complications because could easily negate all efforts surgeon patient achieve a positive result. Very little attention was paid this very serious disease Ukrainian medical journals. The authors have presented information from scientific...

The paper considers the use of hemostasis, biochemical and immunological tests in patients with osteoarthritis large joints (knee, hip) during replacement. Given existing modern laboratory diagnosis markers, which is used on to evaluate health status before after joint

The article contains a review of special literature on methods for selecting legs cement-free endoprostheses. problem the necessity to carry thorough preoperative planning and selection endoprosthesis leg according shape femoral canal is examined. component with proper (proximal, intermediate or distal) type fixation chosen regard proximal thereby maximally possible area contact between implant bone tissue secured. In case conical canal, as rule, authors usually use wedge-shaped fixation....

The article examines pathogenetic and diagnostic roles of the following cytokines in osteoarthrosis large joints: interleukin 1 beta (IL-1β), 1RA (IL-1RA), 4 (IL-4), 6 (IL-6) tumour necrosis factor-alpha (TNF-α). It was revealed that levels IL-1β IL-6 increased from stages I-II to III-VI. IL-1RA concentration patients’ blood at III-VI lower versus I-II, IL-4 being higher only III-IV disease, while TNF-α remained within normal values. Such changes content serum patients with demonstrated...

Total hip replacement due to its effectiveness is the most com­mon treatment for patients with severe diseases of joints. The modern idea choice materials (and methods their application as a pair friction) large joints are described, set scope problems and possible solutions. We characterize some direc­tions improvement artificial human It was em­phasized that so far there no perfect friction in ar­tificial joints, it determines surgeon, taking into account anatomical physiological state...

Hip arthroplasty is the most effective method for treatment of severe stages coxarthrosis, hip injury and their conse­quences. The number replacements throughout world increasing every year. In Ukraine, such operations are necessary in 150 000 patients per Among complications frequent require repeated surgical procedures dislocations femoral head. Dur­ing primary they occur 0.5–10 % cases, after revision surgery risk occurrence increases to 10–25 %. Dislocations head associated with in­tense...

Fracture-related infection following orthopedic surgery, especially in cases of war-related trauma, represents a grave complication. The injuries sustained war often entail severe damage to soft tissues, including significant impairment vessels, nerves, tendons, muscles, and result substantial bone defects. Complicating matters further, these infections involve multidrug-resistant pathogens, making effective treatment challenge. Optimal management patients with combat-related trauma signs...

The article is devoted to the Kharkiv regional branch of All-Ukrainian public organization "Ukrainian Association Orthopedic Surgeons and Traumatologists".

Our previous 3-period crossover study in healthy volunteers comparing the pharmacokinetics of nalbuphine nasal spray Apain with parenteral solution demonstrated high bioavailability and close similarity pharmacokinetic profiles after intranasal intramuscular administration, especially within 30 min postdose. The aim present was a noninferiority assessment vs. injection for pain relief postoperative patients.

Background. Nonsteroidal anti-inflammatory drugs (NSAIDs) are an important drug class for the treatment of osteoarthritis (OA). Despite existing studies on bioequivalence original and generic NSAIDs, comparative related to their clinical efficacy safety limited. The purpose study was compare forms etoricoxib in patients with knee OA. ­Materials ­methods. In open, comparative, randomized, multicenter study, 150 OA were examined: group I — 50 persons who received (60 mg/d 10 days), groups II...

The article is dedicated to academician Korzh Oleksii Oleksandrovych.

The increase in the number of primary arthroplasty procedures has led to an revision for periprosthetic infection and fractures hip stems. problem removing stable stems remains relevant, as lack a unified approach leads duration operations, increased risk complications worsening treatment outcomes. Objective. To review existing methods find out most optimal approaches removal arthroplasties different types fixation. Methods. A systematic literature was conducted using electronic databases...