A5077023478- N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
- Synthesis and Reactions of Organic Compounds
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Catalytic Cross-Coupling Reactions
- Synthesis and Biological Evaluation
- Synthesis and biological activity
- Synthesis and Characterization of Heterocyclic Compounds
- Chemical Reactions and Mechanisms
- Structural and Chemical Analysis of Organic and Inorganic Compounds
- Cyclopropane Reaction Mechanisms
- Synthesis and Reactivity of Sulfur-Containing Compounds
- Synthesis of heterocyclic compounds
- Inorganic and Organometallic Chemistry
- Carbon dioxide utilization in catalysis
- Fluorine in Organic Chemistry
- Organic Chemistry Cycloaddition Reactions
- Synthesis and Reactivity of Heterocycles
- Chemical Reaction Mechanisms
- Click Chemistry and Applications
- Synthesis and properties of polymers
- Crystallography and molecular interactions
- Coordination Chemistry and Organometallics
- Asymmetric Synthesis and Catalysis
- Quinazolinone synthesis and applications
National Academy of Sciences of Ukraine
2003-2021
Institute of Physical and Organic Chemistry
1978-2014
Vasyl' Stus Donetsk National University
2008
Rosa Luxemburg Foundation
2005
The University of Texas at Austin
2003
Donetsk Institute for Physics and Engineering named after O.O. Galkin
1989-1995
Russian Academy of Sciences
1988
Moscow Polytechnic University
1972
Institute for Single Crystals
1967-1968
Institute for Scintillation Materials
1967
A new sterically shielded carbene with branched aromatic substituents (9a) and two palladium halogenide complexes (11a,b) have been prepared. The single crystal X-ray structures of free 9a 10b 11a were determined. Very high catalytic efficiencies evident for the 11a,b when latter employed as catalysts hydrodechlorination chloroarenes p-dichlorobenzene hexachlorobenzene. When optimized, foregoing approach is significantly more effective than those currently known transition metal complexes....
Two new, more convenient methods for the synthesis of 1,2,4-triazol-5-ylidenes are described. Four new have been prepared using these methods: 1-(1-adamantyl)-3,4-diphenyl-1,2,4-triazol-5-ylidene (2a), 1-(1-adamantyl)-3-phenyl-4-(p-bromophenyl)-1,2,4-triazol-5-ylidene (2b), 1-(1-adamantyl)-3-phenyl-4-(α-naphthyl)-1,2,4-triazol-5-ylidene (2c), and 1-(1-adamantyl)-3,4-di(p-bromophenyl)-1,2,4-triazol-5-ylidene (2d). The X-ray crystal structures 2d precursor salt...
Four stable carbenes, 1-tert-butyl-3,4-diaryl-1,2,4-triazol-5-ylidenes 1a-d, including new fluorine-containing compounds 1c,d, react with a malonic ester to afford heterocyclic zwitterionic 5a-d. The reactions more acidic (ethyl acetoacetate, malononitrile and 1,3-dimethylbarbituric acid) proceed substrate deprotonation form the respective azolium salts 6a-c. X-ray crystal structure of 5a was also determined.
In the review an attempt is made for first time to give a systematic account of available literature data recyclisation reactions heterocyclic compounds under influence two-centre nucleophilic agents — hydrazine and its derivatives. The are classified taking into capacity heterocycles undergo such as function structure distribution in reaction centres determining mode recyclisation. Particular attention has been devoted rearrangements involving moiety molecule. mechanisms processes...
The new sterically shielded 1,3,4-trisubstituted 1,2,4-triazol-5-ylidenes 8b–d were synthesized by a three step method starting from 2-phenyl-1,3,4-oxadiazole. syntheses of palladium complexes 9a–d and 10a–d (including the derivatives 9c,d 10a–d) carried out via reactions stable carbenes 8a–d with halogenide salts in THF or toluene solution. Complexes found to be excellent catalysts for reductive dechlorination (hydrodechlorination) p-dichlorobenzene. structures 8c, 9a,b, 10a determined...
The present review deals with the syntheses and properties of individual heteroaromatic carbenes imidazole, 1,2,4-and 1,2,3-triazole series, their fused analogs mesoionic including unprecedented structures such as hyperbasic hypernucleophilic carbenes.Particular emphasis is placed on physical properties, novel chemical transformations, catalytic properties.
The review is focused on new data concerning the syntheses and selected properties of stable heteroaromatic monocarbenes benzimidazole 1,2,4-triazole series, biscarbenes, anionocarbenes cryptocarbenes.The precursors to these compounds are also described.Special attention paid C-H insertion reactions, X-ray structural spectral characteristics carbenes their analogues.
The first tandem autotransformations of heteroaromatic carbenes have been found.These reactions involve cleavage the 1-tert-butyl-3,4-diaryl-1,2,4-triazol-5-ylidenes 1a-d to form benzonitriles and respective carbodiimides, followed by further latter with afford 3,4-diaryl-5-(1-tert-butyl-3-arylamidin-2-yl)-1,2,4-triazoles 5a-d.The X-ray structures carbene 1-tert-butyl-3-phenyl-4-n-bromophenyl-1,2,4-triazol-5ylidene (1a) amidinotriazole...
The stable 3,3'-bridged biscarbenes, 1,4-and 1, 3-bis[1-alkyl-4-phenyl-1,2,4-triazol-5-yliden-3yl]benzenes (5а,b,d) and 1,3-bis[1-(1-adamantyl)-4-phenyl-1,2,4-triazol-5-yliden-3-yl]butane (5c) have been prepared.Treatment of 5b with copper (I) chloride in tetrahydrofuran/acetonitrile solution cobalt (II) acetonitrile or acetonitrile/toluene afforded the biscarbene complex 8.The reactions 5d diphenyldiazomethane sulfur resulted novel bisthione 6 bisazine (7) derivatives, respectively.The...
Abstract The 1‐adamantyl substituted stable carbene 5 and the biscarbene 9 of 1,2,4‐triazole series with sterically shielding groups at position 4 heterocyclic ring (dbmp, dipp) have been synthesized in three steps starting from derivatives 1,3,4‐oxadiazole 1,6 . A new method for preparation 1,3,4‐triaryl‐1,2,4‐triazol‐5‐ylidenes ( 14 a‐c ) has also proposed includes Vilsmeier reaction 2‐benzoyl‐1‐formylphenylhydrazine phosphorus chloroxide aromatic amines, followed by deprotonation obtained...
A novel 1,3-dimethyl-1,3-di-(1-adamantyl)formamidinium perchlorate has been prepared via the Vilsmeier-Haack reaction of N-methyl-N-(1-adamantyl)formamide and N-methyl-N-(1-adamantyl)amine in a mixture phosphorus oxychloride benzene.The new formamidinium salt was found to undergo addition-elimination reactions when treated with sodium hydride acetonitrile or propionitrile solution, thereby forming corresponding β-[methyl(1-adamantyl)amino]acrylonitriles N-methyl-N-(1-adamantyl)amine.The 1 H...
РЕДАКЦІЙНА КОЛЕГІЯ Б. Д. Грищук -доктор хімічних наук, професор (головний редактор) Я. Г. Бальон В. С. Броварець М. Вовк І. Короткіх О. Лявинець П. Новіков Обушак Станінець Швайка Барановський -кандидат доцент
For carbenes as ambiphilic compounds there is no single scale for estimating their electron properties.Aim. To consider the known methods of electron-donating and electron-withdrawing properties carbenes, first all, created by authors article, show possibilities in predicting carbenes.Materials methods. The studies were performed using DFT (B3LYP5/6-311G/RHF) method to estimate proton affinity, (B3LYP5/3-21G/RHF B3LYP5/3-21G/UHF) determine chemical hardness electronic indices.Results...
A series of new stable halogenated carbenes, 1- tert -butyl-3,4-diaryl-1,2,4-triazol-5-ylidenes, has been synthesized.