A5046369601- Physical Activity and Health
- Cancer Risks and Factors
- Nutritional Studies and Diet
- Cancer survivorship and care
- Obesity, Physical Activity, Diet
- Cancer-related cognitive impairment studies
- Sleep and related disorders
- Childhood Cancer Survivors' Quality of Life
- Sleep and Wakefulness Research
- Diet and metabolism studies
- Nutrition and Health in Aging
- Metabolism, Diabetes, and Cancer
- Obstructive Sleep Apnea Research
- Metabolomics and Mass Spectrometry Studies
- Cancer, Lipids, and Metabolism
- Liver Disease Diagnosis and Treatment
- Chronic Kidney Disease and Diabetes
- Urban Transport and Accessibility
- Cardiovascular Health and Risk Factors
- Estrogen and related hormone effects
- Circadian rhythm and melatonin
- Health disparities and outcomes
- Statistical Methods and Inference
- Antioxidant Activity and Oxidative Stress
- Statistical Methods in Clinical Trials
Human Longevity (United States)
2021-2025
University of California, San Diego
2016-2025
Moores Cancer Center
2013-2024
UC San Diego Health System
2019-2024
Phoenix (United States)
2023
Children's Mercy Hospital
2021
Kaiser Permanente Washington Health Research Institute
2021
Qualcomm (United States)
2021
Center for Children
2021
University of Missouri–Kansas City
2021
Evidence is lacking that a dietary pattern high in vegetables, fruit, and fiber low total fat can influence breast cancer recurrence or survival.
Diabetic kidney disease is the leading cause of ESRD, but few biomarkers diabetic are available. This study used gas chromatography-mass spectrometry to quantify 94 urine metabolites in screening and validation cohorts patients with diabetes mellitus (DM) CKD(DM+CKD), DM without CKD (DM–CKD), healthy controls. Compared levels controls, 13 were significantly reduced DM+CKD (P≤0.001), 12 remained significant when compared DM–CKD cohort. Many differentially expressed water-soluble organic...
Purpose Single-variable analyses have associated physical activity, diet, and obesity with survival after breast cancer. This report investigates interactions among these variables. Patients Methods A prospective study was performed of 1,490 women diagnosed treated for early-stage cancer between 1991 2000. Enrollment an average 2 years postdiagnosis. Only seven were lost to follow-up through December 2005. Results In univariate analysis, reduced mortality weakly higher vegetable-fruit...
To examine whether treatment of obstructive sleep apnea (OSA) with continuous positive airway pressure (CPAP) in patients Alzheimer's disease (AD) results better cognitive function.
We explored whether breast cancer outcomes are associated with endoxifen and other metabolites of tamoxifen examined potential correlates concentration levels in serum including cytochrome P450 2D6 (CYP2D6) metabolizer phenotype body mass index (BMI). Concentration tamoxifen, endoxifen, 4-hydroxytamoxifen (4OH-tamoxifen), N-desmethyltamoxifen (ND-tamoxifen) were measured from samples taken 1,370 patients estrogen receptor (ER)-positive who participating the Women's Healthy Eating Living...
Background:Studies have shown self-monitoring can modify health behaviors, including physical activity (PA). This study tested the utility of a wearable sensor/device (Fitbit® One™; Fitbit Inc., San Francisco, CA) and short message service (SMS) text-messaging prompts to increase PA in overweight obese adults.Materials Methods:Sixty-seven adults wore One tracker for 6 weeks; half were randomized also receive three daily SMS-based prompts. The consisted instant feedback on performance Web...
Prevalence of walking and cycling for transport is low varies greatly across countries. Few studies have examined neighborhood perceptions related to in different Therefore, it challenging prioritize appropriate built-environment interventions. The aim this study was examine the strength shape relationship between adults' diverse environments. As part International Physical activity Environment Network (IPEN) adult project, self-reported data were taken from 13,745 adults (18-65 years)...
SciEnTiFic invESTigATiOnSintroduction: Obstructive sleep apnea (OSA) is common among patients with Alzheimer's disease (AD).Untreated OSA exacerbates the cognitive and functional deficits.Continuous positive airway pressure (CPAP) has recently been shown to have beneficial effects on cognition in AD.Little attention focused long-term benefits of CPAP these patients.Methods: This was an exploratory study sustained use (mean = 13.3 months, SD 5.2) a subset participants from initial 6-week...
Women with breast cancer are thought to be vulnerable depression for reasons associated impact of diagnosis, treatment, and metabolic/endocrine changes. While the literature shows that most these women do not become clinically depressed, 15% 30% report elevated depressive symptoms may important. The purpose was identify determine relative importance predictors in treated early-stage cancer.A total 2,595 (< or = 4 years following completion initial treatment cancer) provided data on...
Abstract Objective : The concept of symptom clusters is relatively new in cancer patients' management. This study, which spanned four cycles chemotherapy, combined three commonly seen pre‐treatment symptoms patients (i.e. sleep disturbances, fatigue and depression) into one cluster, to explore the associations between cluster categories longitudinal profiles these same during chemotherapy. Methods was a prospective study. Seventy‐six women with newly diagnosed stage I–III breast cancer,...
Self-reported diabetes has been associated with poor breast cancer outcomes. Research is needed to investigate the relationship between biologically determined glycemic control and prognosis.
Rodent studies demonstrate that prolonged fasting during the sleep phase positively influences carcinogenesis and metabolic processes are putatively associated with risk prognosis of breast cancer. To our knowledge, no in humans have examined nightly duration cancer outcomes.To investigate whether predicted recurrence mortality among women early-stage and, if so, it was factors for poor outcomes, including glucoregulation (hemoglobin A1c), chronic inflammation (C-reactive protein), obesity,...
BACKGROUND Increasing physical activity can improve cognition in healthy and cognitively impaired adults; however, the benefits for cancer survivors are unknown. The current study examined a 12‐week intervention, compared with control condition, on objective self‐reported among breast survivors. METHODS Sedentary were randomized to an exercise arm (n = 43) or 44). At baseline at 12 weeks, was measured National Institutes of Health Cognitive Toolbox, using Patient‐Reported Outcomes...
REPORT insomnia symptoms. 1,2 There is also evidence suggesting that breast cancer patients constitute the subgroup of most at risk for experiencing sleep difficulties. 3,4 In addition to resulting in restless (i.e., increased activity during night), and its treatment may reduce daytime activity.Although data are rather sparse, there some suggest have disturbed circadian rhythms.6][7][8][9] But few examined variables before patients.Some on rhythms be altered even prior initiation...