- Genomics and Phylogenetic Studies
- Vitamin C and Antioxidants Research
- Genetic diversity and population structure
- Spaceflight effects on biology
- Space Exploration and Technology
- Space exploration and regulation
- Spacecraft Design and Technology
- Genetics, Aging, and Longevity in Model Organisms
- Vitamin K Research Studies
- Simulation Techniques and Applications
- Sports injuries and prevention
- Meteorological Phenomena and Simulations
- Insect and Arachnid Ecology and Behavior
- Mechanics and Biomechanics Studies
- Porphyrin Metabolism and Disorders
- Genetics, Bioinformatics, and Biomedical Research
- Physiological and biochemical adaptations
- Antioxidant Activity and Oxidative Stress
- Icing and De-icing Technologies
- Body Composition Measurement Techniques
- Microbial metabolism and enzyme function
- Plant Reproductive Biology
- Photoreceptor and optogenetics research
- Artificial Immune Systems Applications
- Wind Energy Research and Development
Universidade do Porto
2022-2024
i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto
2018-2024
Instituto de Biologia Molecular e Celular
2022-2024
Escola Superior de Saúde Egas Moniz
2022
European Astronaut Centre
2003-2007
Linde (Germany)
2007
European Space Astronomy Centre
2007
Abstract Background Vitamin C (VC) is an indispensable antioxidant and co-factor for optimal function development of eukaryotic cells. In animals, VC can be synthesized by the organism, acquired through diet, or both. single synthesis pathway described in penultimate step catalysed Regucalcin, last l -gulonolactone oxidase (GULO). The GULO gene has been implicated only, while Regucalcin shown to have multiple functions mammals. Results Both found non-bilaterian, protostome deuterostome...
L-ascorbate (Vitamin C) is an important antioxidant and co-factor in eukaryotic cells, mammals it indispensable for brain development cognitive function. Vertebrates usually become auxothrophs when the last enzyme of synthetic pathway, L-gulonolactone oxidase (GULO), lost. Since Protostomes were until recently thought not to have a GULO gene, they considered be Vitamin C. By performing phylogenetic analyses with tens non-Bilateria Protostomian genomes, shown, that gene present Placozoa,...
This study aimed to (i) characterise the body composition of professional and semi-professional male futsal players, (ii) assess validity commonly used equations estimate FM%, (iii) develop cross-validate a futsal-specific FM% prediction equation. In cross-sectional design, 78 adult players were assessed for mass, stature, skinfolds, girths as per International Society Advancement Kinanthropometry protocol completed dual-energy X-ray absorptiometry (DXA) scan reference data. Using...
Abstract When inferring the evolution of a gene/gene family, it is advisable to use all available coding sequences (CDS) from as many species genomes possible in order infer and date gene duplications losses. Nowadays, this means using hundreds or even thousands CDSs, which makes inferred phylogenetic trees difficult visualize interpret. Therefore, useful have an automated way collapsing large according taxonomic term decided by user (family, class, order, for instance), highlight minimal...
SEDA (SEquence DAtaset builder) is a multiplatform desktop application for the manipulation of FASTA files containing DNA or protein sequences. The convenient graphical user interface gives access to collection simple (filtering, sorting, file reformatting, among others) and advanced (BLAST searching, domain annotation, gene sequence alignment) utilities not present in similar applications, which eases work life science researchers working with and/or sequences, especially those who have no...
Abstract The vast amount of genome sequence data that is available, and predicted to drastically increase in the near future, can only be efficiently dealt with by building automated pipelines. Indeed, Earth Biogenome Project will produce high-quality reference sequences for all 1.8 million named living eukaryote species, providing unprecedented insight into evolution genes gene families, thus on biological issues. Here, new modules annotation, further BLAST search algorithms, multiple...
Introduction: Ascaris lumbricoides is a nematode parasite that can infect humans, being the main cause of soil-transmitted helminth infections, which have varied outcomes, from gastrointestinal or respiratory disorders, to surgical emergencies. Its incidence occurs mainly in tropical and temperate zones, with greater number cases reported pediatric population. Materials methods: This clinical case report accompanied by brief review literature on 17-year-old male patient, indigenous race,...