David Wetherell

ORCID: 0000-0001-5783-3642
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About
Contact & Profiles
Research Areas
  • Prostate Cancer Diagnosis and Treatment
  • Pediatric Urology and Nephrology Studies
  • Prostate Cancer Treatment and Research
  • Urologic and reproductive health conditions
  • Radiopharmaceutical Chemistry and Applications
  • Kidney Stones and Urolithiasis Treatments
  • Renal cell carcinoma treatment
  • Web and Library Services
  • Urological Disorders and Treatments
  • Intraocular Surgery and Lenses
  • Trace Elements in Health
  • Ureteral procedures and complications
  • Urinary Bladder and Prostate Research
  • Testicular diseases and treatments
  • Health Literacy and Information Accessibility
  • Social Media in Health Education
  • Gallbladder and Bile Duct Disorders
  • Urinary and Genital Oncology Studies
  • Surgical Simulation and Training
  • MicroRNA in disease regulation
  • Renal and related cancers
  • Muscle and Compartmental Disorders
  • Vascular Malformations and Hemangiomas
  • Cancer, Hypoxia, and Metabolism
  • Magnetic and Electromagnetic Effects

The University of Melbourne
2012-2025

Austin Health
2012-2023

Western Health
2021-2022

The Royal Melbourne Hospital
2022

Monash Health
2021

Austin Hospital
2012-2015

Introduction: The incidence of urolithiasis is increasing in the Western population. Significant advances ureteroscopy and stone fragmentation energy sources have resulted a paradigm shift management. We aimed to assess current state management Australia over last 15 years using population-based data. Methods: Medicare databases were accessed rebate codes pertaining ureteroscopy, extracorporeal shockwave lithotripsy (SWL), percutaneous nephrolithotomy (PCNL) extracted per state, year, gender...

10.1089/end.2016.0513 article EN Journal of Endourology 2016-09-15

Objectives To estimate the cost effectiveness of local anaesthetic (LA) transperineal prostate biopsy (TPB) compared to general (GA) TPB, considering both hospital/health system and societal perspectives. Patients Methods Individual‐patient data from a prospective pilot study 80 patients who underwent LA ( n = 40) or GA TPB according patient preference was used. A cost‐effectiveness analysis conducted using decision tree model cancer detection rates, perioperative return work considerations...

10.1111/bju.16722 article EN cc-by-nc BJU International 2025-04-04

To compare data on transperineal template biopsy (TPTB) under general anesthesia (GA) compared with local (LA) procedures using the PrecisionPoint™ Transperineal Access System (PPTAS) in relation to tolerability, cancer detection rate, complications, and cost.A prospective pilot cohort study of patients undergoing was performed. Patients were excluded if they had concurrent flexible cystoscopy or language barriers. a choice GA LA. A questionnaire Days 0, 1, 7, 30 applied. The primary outcome...

10.1002/bco2.106 article EN cc-by BJUI Compass 2021-09-10

Transperineal biopsy (TPB) of the prostate has been increasingly utilized as it reduced infection risks. Traditionally however, is performed under general anaesthesia, thus carries a differing set Recently, new studies have TPB local anaesthesia with success. In present study, we explored our experience performing in an Australian cohort.

10.1111/ans.17593 article EN ANZ Journal of Surgery 2022-03-10

Spermatocytic seminoma (SCS) with sarcoma is an extremely rare testicular tumor only 11 cases previously described in the literature. We present 12th case of SCS a 29-year-old male. itself uncommon germ cell relatively indolent clinical course that mostly affects males around fifth decade life. Sarcomatous differentiation occurs 5% to 6% and correlates higher possibility metastatic disease poor prognosis. Clinically, this manifests as slow-growing mass often accelerated period secondary...

10.4111/kju.2013.54.12.884 article EN Korean journal of urology 2013-01-01

Health care websites provide a valuable resource of health information to online consumers, especially patients. Official surgical and medical society should be reliable first point contact.The primary aim this study was quantitatively assess for content highlight the essential features required high-quality, user-friendly website.Twenty specialty association from each regions, Australia, UK, Canada, Europe, USA were selected total 100 websites. Medical specialities consistent across region....

10.2196/ijmr.3963 article EN cc-by Interactive Journal of Medical Research 2015-03-27

To assess whether metformin reduces radio-resistance and increases survival in men undergoing external beam radiation therapy (EBRT) for prostate cancer (PCa), to determine its effect on hypoxia inducible factor 1-α (HIF1α).All patients treated with curative intent EBRT PCa at a major centre between 2000 2007 were included this study. The outcome measures of time biochemical failure (BF), metastasis, PCa-specific mortality overall (OS) analysed those taking vs not, using competing risk Cox...

10.1111/bju.14709 article EN BJU International 2019-04-23

Zinc ions (Zn2+) are known to influence cell survival and proliferation. However the homeostatic regulation of Zn2+ their role in prostate cancer (PC) progression is poorly understood. Therefore subcellular distribution uptake PC cells were investigated. Inductively coupled plasma mass spectroscopy fluorescent microscopy with Zn2+-specific probe FluoZin-3 used quantify total free Zn2+, respectively, normal epithelial line (PNT1A) three human lines (PC3, DU145 LNCaP). The effects treatment on...

10.18632/oncotarget.23893 article EN Oncotarget 2018-01-03

True metastatic ureteric lesions are exceptionally rare when sourced from any primary tumour. Primary prostatic cancer metastasis to the ureter is understandably even more atypical with very few cases reported in current literature. intramural disease deposited prostate an rarer occurrence. We present a case of man his mid-60s left-sided hydronephrosis setting biochemical recurrence Gleason 9 cancer. Initially misdiagnosed as obstruction secondary mass effect large trigonal lesion,...

10.1136/bcr-2017-222480 article EN BMJ Case Reports 2018-01-06

Objective To present the early results of a new technique for treatment renal cell carcinoma with intra‐cardiac tumour extension and Budd–Chiari syndrome. Patients Methods The first stage involves transdiaphragmatic debulking right heart, inferior vena cava (IVC) hepatic veins via median sternotomy, followed by purse‐string suture placed in IVC below veins. second is performed separately en bloc resection affected kidney, vascular reconstruction an abdominal incision. Results Three five...

10.1111/bju.16257 article EN cc-by-nc-nd BJU International 2023-12-16

Partial nephrectomy has become the 'gold standard" for treatment of suspicious renal masses when surgery is required. The advantages in terms preservation without compromising cancer control are well accepted provided lesions carefully selected. challenge now to improve upon patient selection partial nephrectomy, optimising surgical technique and also considering how reduce ischaemic time kidney that will remain. This article explores such issues summarises current status nephrectomy.

10.6000/1927-7229.2012.01.01.14 article EN Journal of Analytical Oncology 2012-01-28
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