A5019945679- Hydraulic and Pneumatic Systems
- Antifungal resistance and susceptibility
- Advanced Sensor and Control Systems
- Lipid metabolism and biosynthesis
- Peptidase Inhibition and Analysis
- Industrial Technology and Control Systems
- Heavy metals in environment
- Evaluation Methods in Various Fields
- Plant Stress Responses and Tolerance
- Antenna Design and Analysis
- Microbial Metabolic Engineering and Bioproduction
- Ocean Waves and Remote Sensing
- Metalloenzymes and iron-sulfur proteins
- Numerical methods in engineering
- Magnetic and Electromagnetic Effects
- Advanced Nanomaterials in Catalysis
- Endoplasmic Reticulum Stress and Disease
- Fractional Differential Equations Solutions
- Real-time simulation and control systems
- Advanced SAR Imaging Techniques
- ATP Synthase and ATPases Research
- Microwave Imaging and Scattering Analysis
- Energy Harvesting in Wireless Networks
- Wireless Power Transfer Systems
- Heavy Metals in Plants
Guilin Medical University
2024
Harbin Institute of Technology
2007-2023
Beijing Institute of Technology
2008-2023
Anhui Provincial Hospital
2020-2023
Tianjin University of Traditional Chinese Medicine
2011-2022
Shanghai Municipal Center For Disease Control Prevention
2022
Inner Mongolia University
2021
Nanjing University of Information Science and Technology
2016-2021
Harbin University of Science and Technology
2021
Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
2021
The maintenance of cellular calcium homeostasis is associated with signalling transduction and the functions many membrane compartments, especially endoplasmic reticulum (ER) function. ER-localized proteins that serve to maintain ER in Candida albicans are still unclear. In this study, Spf1, putative C. homologue Saccharomyces cerevisiae P-type ATPase ScSpf1, was investigated for its roles homeostasis, hyphal development virulence. We constructed an Spf1 null mutant which showed decreased...
Candida albicans morphogenesis and gastrointestinal colonization are closely associated with the pathogenicity of this pathogen. This study investigated in vitro vivo effect verapamil, a calcium channel blocker, on these processes. Exposure to ≥ 10 μg mL(-1) verapamil led significant decrease C. hyphal cells. The ability adhere polystyrene surface buccal epithelial cells was inhibited by exposure 20 verapamil. Detection Hwp1-green fluorescent protein fusion showed that expression transport...
A novel carbon doping strategy induced by an organic salt is successfully developed. Improved carrier separation and exciton binding energies (<italic>E</italic><sub>b</sub>) are achieved on C-doped Bi<sub>24</sub>O<sub>31</sub>Cl<sub>10</sub>, which provides excellent photocatalytic CO<sub>2</sub> reduction persistent <sup>1</sup>O<sub>2</sub> generation.
Since titanium dioxide (TiO<sub>2</sub>) nanomaterials are widely implemented in various fields, their safety and toxicity receive detailed investigation.
RNA-binding proteins play critical roles in post-transcriptional regulation by interacting with RNA to regulate various cellular processes. Inferring the binding signals and sequence patterns of these interactions is essential for elucidating mechanisms underlying gene expression regulation. In this study, we present RBPSignal, a deep learning-based computational tool designed predict RBP on RNAs identify potential motifs associated interactions. RBPSignal leverages learning framework trains...
Candida albicans is an important opportunistic pathogen, causing both superficial mucosal infections and life-threatening systemic diseases. Iron acquisition factor for pathogen–host interaction also a significant element the pathogenicity of this organism. Ferric reductases, which convert ferric iron into ferrous iron, are components high-affinity uptake system. Sequence analyses have identified at least 17 putative reductase genes in C. genome. CFL1 was first albicans. However, little...
Hepatocellular carcinoma (HCC) is the most common liver cancer with high mortality. Here, we found that hnRNPU overexpressed in HCC tissues and correlated poor prognosis of patients. Besides, significance regulating proliferation, apoptosis, self‐renewal, tumorigenic potential cells. Mechanismly, c‐Myc regulates expression at transcriptional level, meanwhile, stabilizes mRNA c‐MYC. We regulatory loop exerts a synergistic effect on proliferation self‐renewal HCC, promotes progression. Taken...
Iron is an essential nutrient required for the growth and metabolism in Candida albicans. Here, we first time identified Mrs4 as a new member of mitochondrial carrier family C. Our experiments revealed that albicans (CaMrs4) localized to mitochondria morphology. We found CaMrs4 cell growth, mrs4Δ/Δ mutant showed more severe defect iron deficiency. Deletion MRS4 affected cellular content by altering expression regulon genes albicans, such AFT2, SMF3, FTR1 ISU1. Aft2 factor functions negative...
Application of mu theory in the electrohydraulic load simulator is studied. Robust control strategy put forward. The a complicated mechanical-electronic-hydraulic compound system, moreover it strong coupling and time-varying controlled object. Synthetically considering uncertainties such as parameter perturbations, model perturbations external disturbances etc., robust force controller designed using synthesis theory. stability performance are analyzed by values system which used. Moreover,...
Unsaturated fatty acids (UFAs) are key compounds which have important roles in maintaining cell membrane physiological functions and the adaption to tough conditions. Defects of acid desaturases will change cellular UFA constitution. Pichia pastoris GS115 has four desaturase genes, namely FAD9A, FAD9B, FAD12 FAD15. Their products catalyze synthesis three kinds UFAs, oleic (catalyzed by Fad9A Fad9B), linoleic Fad12) α-linolenic Fad15), respectively. In this study, we found that deletion led...