- Food Quality and Safety Studies
- Algal biology and biofuel production
- Phytochemicals and Antioxidant Activities
- Ginseng Biological Effects and Applications
- Pharmacological Effects of Natural Compounds
- Biofuel production and bioconversion
- Seaweed-derived Bioactive Compounds
- Medicinal Plants and Neuroprotection
- Microbial Metabolic Engineering and Bioproduction
- Fungal Biology and Applications
- Agriculture, Soil, Plant Science
- Natural product bioactivities and synthesis
- Ecology and Conservation Studies
- Plant-Derived Bioactive Compounds
- Skin Protection and Aging
- Microbial Inactivation Methods
- Protein Hydrolysis and Bioactive Peptides
- Phytochemistry and Biological Activities
- Medicinal Plants and Bioactive Compounds
- Healthcare and Venom Research
- melanin and skin pigmentation
- Hydrogels: synthesis, properties, applications
- Biodiesel Production and Applications
- Surfactants and Colloidal Systems
- Neuroscience and Neuropharmacology Research
Kangwon National University
2008-2024
University of Malaya
2020-2024
University Malaya Medical Centre
2020-2024
Seowon University
2012-2019
Korea Advanced Institute of Science and Technology
2017
Korea Institute of Ocean Science and Technology
2012
Hoseo University
2010
Kyung Hee University
2006
In the present study, we studied neuroprotective effects of berberry extract (BE) against ischemic damage and temporal spatial alterations N-methyl-D-aspartate receptor type 1 (NR1) NR2A/2B immunoreactivities in gerbil hippocampal CA1 region after transient ischemia to examine anti-ischemic its role forebrain ischemia. vehicle-treated group, percentage cresyl violet positive pyramidal cells was about 11.4% compared sham-operated group 4 d insult. BE showed ischemia-reperfusion. BE-treated...
Marine microalga, Scenedesmus sp., which is known to be suitable for biodiesel production because of its high lipid content, was subjected the conventional Folch method extraction combined with high-pressure homogenization pretreatment process at 1200 psi and 35°C. Algal yield about 24.9% through this process, whereas only 19.8% can obtained by following a procedure using solvent, chloroform : methanol (2 1, v/v). Present approach requires 30 min time moderate working temperature 35°C as...
Abstract Gastrodin is one of the natural compound isolated from Gastrodia elata and has known anticonvulsant effects, although exact pharmacological principles this its effects on other aspects γ‐aminobutyric acid (GABA) metabolism in vivo have not been explored. Therefore, present study, gastrodin GABA gerbil hippocampus were examined, an effort to identify antiepileptic characteristics substance. reduced seizure score treated group, immunoreactivities synthetic enzymes transporters...
Spirulina maxima is a microalgae which contains flavonoids and other polyphenols. Although 70% ethanol extract (SM70EE) has diverse beneficial effects, its effects on neurotoxicity have not been fully understood. In this study, we investigated the neuroprotective of SM70EE against trimethyltin (TMT)-induced in HT-22 cells. inhibited cleavage poly-ADP ribose polymerase (PARP). Besides, ROS production was decreased by down-regulating oxidative stress-associated enzymes. increased factors...
ABSTRACT This study was designed to characterize the viability and potential virulence of bofilm-forming Salmonella enterica serovar Typhimurium under different pH levels, ranging from 5 7. The plate count method real-time reverse transcription-PCR (RT-PCR) were used evaluate survival S. grown in Trypticase soy broth (TSB) adjusted 5, 6, 7 (TSB-5, TSB-6, TSB-7, respectively) at 37°C for 10 days. In TSB-5 numbers viable cells estimated by using RT-PCR greater than culturable counts enumerated...
Glutamate (an endogenous excitatory neurotransmitter) at high concentrations contributes to the development of neurodegenerative diseases. Aronia melanocarpa (A. melanocarpa) berries contain anthocyanins and have antioxidant activities. In this study, we evaluated whether A. could protect neuronal cells against glutamate-induced oxidative stress.A. exerted a protective effect cytotoxicity in HT22 mouse hippocampal by MTT assay. We stress parameters including ROS level, intracellular Ca2+...
This study was designed to evaluate the combined effects of probiotic fermentation and high-pressure extraction (HPE) on functional properties Codonopsis lanceolata. The ground C. lanceolata samples were anaerobically fermented with Lactobacillus acidophilus ADH, Bifidobacterium longum B6, rhamnosus GG, or paracasei at 37 °C for 10 days subjected 500 MPa 50 30 min. yields noticeably increased 29−32% by HPE. B. longum-fermented extracted high pressure (BLF-HPE) exhibited highest antimicrobial...
더덕(Codonopsis lanceolata Bench. et Hook.)은 예로부터 한방에서 염증을 제거하는 작용이 있고, 인후염이나 림프절 결핵에 효과가 있으며 오랫동안 먹어도 독성이 없는 상품(上品)의 한약자원이다. 민간에서는 고혈압 및 당뇨병 치료에도 이용하며, 최근에는 항암효과와 변비 예방 치료에 효능이 있는 식이섬유가 다량 함유되어 것이 밝혀져 약용을 겸한 건강식품으로 주목을 받는 산채이다. 본 연구는 등급 외 더덕을 이용하여 발효더덕을 제조한 후 약이성 음식으로의 활용을 위한 가능성을 타진하고자 계획ㆍ수행되었다. 따라서 발효더덕의 영양성분 분석을 통한 식품영양학적 접근을 하고자 하였다. 접근에서의 일반성분은 건량기준으로 당질(79.3%) 조단백질 (13.0%), 조지방(2.40%) 조회분(5.3%)이었고 각 시료 100 g의 함유 열량은 390.5 ㎉로 분석되었으며, 총 식이섬유소 함량은 당질 중 47.4%를 나타내었다. 또한, 18종의 아미노산으로 구성되었으며...
In general, stepwise hot steaming process is known to be effective in improving its biological activities; however, not much employed processing Codonopsis lanceolata due hardness. this study, C. was first pretreated with warm water at and for two hours, then steamed 3 hours. Antioxidant activities of 70% ethanol extracts were compared the extract from solvent: 41.58% vs 8.98% DPPH radical scavenging activity adding extract, respectively. Reducing power fresh also measured as 1.39 0.71....
In the current study, we show anti-oxidative and hypocholesterol effects of aloe vera in liver. Male specific pathogen-free (SPF) Fischer 344 rats were randomly assigned to one four groups: Group A (control) was fed test chow without supplementation; B a diet containing 1% (per weight basis) freeze-dried filet; C charcoal-processed, D a-charcoal-processed freeze-dried, whole leaf (0.02% per drinking water. Our results that life-long intake had superior action against lipid peroxidation vivo,...