A5042596465- Liver physiology and pathology
- Organ Transplantation Techniques and Outcomes
- Pancreatic function and diabetes
- Hepatitis B Virus Studies
Brigham and Women's Hospital
2020
Harvard University
2020
Abstract The liver plays a central role in metabolism, protein synthesis and detoxification. It possesses unique regenerative capacity upon injury. While many factors regulating cellular proliferation during repair have been identified, the mechanisms by which injured maintains vital functions prior to tissue recovery are unknown. Here, we identify new phase of functional compensation following acute injury that occurs proliferation. By coupling single-cell RNA-seq with situ transcriptional...
The liver plays a central role in metabolism, protein synthesis and detoxification. It possesses unique regenerative capacity upon injury. While many factors regulating proliferation during repair have been identified, the mechanisms by which injured maintains vital functions prior to tissue recovery are unknown. Here, we identify new phase of functional compensation following acute injury that occurs cellular proliferation. By coupling single‐cell RNA‐seq with situ transcriptional analyses...