- Animal Nutrition and Physiology
- Influenza Virus Research Studies
- RNA and protein synthesis mechanisms
- Animal Virus Infections Studies
- Livestock and Poultry Management
- Protein Structure and Dynamics
- Meat and Animal Product Quality
- Viral gastroenteritis research and epidemiology
- Philosophical and Theoretical Analysis
- Advanced Biosensing Techniques and Applications
- Viral Infections and Vectors
- Rousseau and Enlightenment Thought
- Rabbits: Nutrition, Reproduction, Health
- Salmonella and Campylobacter epidemiology
- SARS-CoV-2 and COVID-19 Research
- Animal Disease Management and Epidemiology
- Historical and Scientific Studies
- Animal Behavior and Welfare Studies
Utrecht University
2019-2025
Highlights•Influenza A virus hemagglutinins exclusively bind either NeuAc or NeuGc sialic acids•Structural studies reveal this specificity at the atomic level•Influenza neuraminidases are able to cleave NeuGc•NeuGc represents a species barrierSummaryA barrier for influenza is differential expression of acid, which can be α2,3-linked avians α2,6-linked human viruses. The hosts also express other species-specific acid derivatives. One major modification C-5 N-glycolyl (NeuGc), instead N-acetyl...
In late 2015, an epizootic of Highly Pathogenic Avian Influenza (H5Nx) was registered in Southwestern France, including more than 70 outbreaks commercial poultry flocks. Phylogenetic analyses suggested local emergence H5 viruses which differed from A/goose/Guangdong/1/1996 clade 2.3.4.4b lineage and shared a unique polybasic cleavage site their hemagglutinin protein. The present work provides overview the pathobiological picture associated with this naturally infected chickens, guinea fowls...
Enterococci infections may result in acute and chronic disease. Lesions, such as osteomyelitis, arthritis, or endocarditis, depend on the Enterococcus species involved. In this case report, an outbreak of hirae-associated endocarditis affecting young broiler breeders is presented. On a rearing farm with 46,500 breeders, slight increased mortality (1.02%-1.42%) within female line was observed between 2 6 wk posthatch (ph). Between days 12 47 ph, 256 birds were pathologically examined,...
Avian coronaviruses cause major global problems in the poultry industry. As causative agents of huge economic losses, detection and understanding molecular determinants viral tropism are ultimate importance. Here, we set out to study those parameters obtained in-depth insight into virus-host interactions guinea fowl coronavirus (GfCoV). Our data indicate that diversity GfCoV attachment proteins results differences degrees affinity for glycan receptors, as well altered avidity intestinal...
Colibacillosis is a poultry disease that negatively affects welfare and causes economic losses. Treatment with antibiotics raises concerns on antimicrobial resistance. Consequently, alternative approaches to enhance resilience are needed. Access feed water directly after hatch (early feeding) may at later ages. Additionally, high eggshell temperature (EST) during mid incubation improve chick quality hatch, supporting potential positive effects of early feeding. Effects EST [37.8°C (control)...
Broilers kept above their respective thermoneutral zone, aim behavior at dissipating heat rather than the intake of feed, leading to a reduction body weight gain. It is not known whether in growth performance broilers can be fully attributed feed intake. The current experiment was investigate Ross 308 and Korat relation reduced when high ambient temperatures. following treatments were provided: 1. ad libitum fed housed under temperature conditions; 2. climate controlled 3. pair-fed with...