A5089784611- Pelvic floor disorders treatments
- Urinary Bladder and Prostate Research
- Urinary Tract Infections Management
- Anorectal Disease Treatments and Outcomes
- Urological Disorders and Treatments
- Pelvic and Acetabular Injuries
- Ureteral procedures and complications
- Diverticular Disease and Complications
- Hernia repair and management
- Sexual function and dysfunction studies
- Anesthesia and Pain Management
- Bladder and Urothelial Cancer Treatments
- Urologic and reproductive health conditions
- Urinary and Genital Oncology Studies
- Prostate Cancer Diagnosis and Treatment
- Innovations in Medical Education
- Botulinum Toxin and Related Neurological Disorders
- Gut microbiota and health
- Pregnancy-related medical research
- Pressure Ulcer Prevention and Management
- Female Genital Mutilation/Cutting Issues
- Endometriosis Research and Treatment
- Neuroscience of respiration and sleep
- Health and Medical Research Impacts
- Pain Management and Treatment
Duke University
2016-2025
Duke Medical Center
2014-2025
Institute for Female Pelvic Medicine and Reconstructive Surgery
2018-2024
Duke University Health System
2010-2023
Duke University Hospital
2000-2022
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2019-2022
University of North Carolina at Chapel Hill
2021
University of New Mexico
2017-2020
Duke Raleigh Hospital
2019
Brown University
2017-2019
Urodynamic studies are commonly performed in women before surgery for stress urinary incontinence, but there is no good evidence that they improve outcomes.
Women without stress urinary incontinence undergoing vaginal surgery for pelvic-organ prolapse are at risk postoperative incontinence. A midurethral sling may be placed the time of repair to reduce this risk.
<h3>Importance</h3> Women with refractory urgency urinary incontinence are treated sacral neuromodulation and onabotulinumtoxinA limited comparative information. <h3>Objective</h3> To assess whether is superior to in controlling episodes of incontinence. <h3>Design, Setting, Participants</h3> Multicenter open-label randomized trial (February 2012-January 2015) at 9 US medical centers involving 381 women <h3>Interventions</h3> Cystoscopic intradetrusor injection 200 U (n = 192) or 189)....
No AccessJournal of UrologyAdult Urology1 Jun 2009Outcome a Randomized, Double-Blind, Placebo Controlled Trial Botulinum A Toxin for Refractory Overactive Bladder Michael K. Flynn, Cindy L. Amundsen, MaryAnn Perevich, Fan Liu, and George D. Webster FlynnMichael Flynn Division Urogynecology, Department Obstetrics Gynecology, University Rochester, New York , AmundsenCindy Amundsen Duke Medical Center, Durham, North Carolina PerevichMaryAnn Perevich Urology, LiuFan Liu Center Research...
The etiology of postmenopausal recurrent urinary tract infection (UTI) is not completely known, but the microbiome thought to be implicated. We compared in menopausal women with UTIs age-matched controls, both absence acute infection.This a cross-sectional analysis baseline data from 64 enrolled longitudinal cohort study. All were using topically applied vaginal estrogen. Women >55 years age following groups enrolled: 1) on daily antibiotic prophylaxis, 2) prophylaxis and 3) controls without...
We evaluate the characteristics of women with bladder endometriosis successfully treated hormonal therapy.The records 14 patients a mean age 48.7 years (range 26 to 71) diagnosed on cystoscopic evaluation were reviewed for presenting complaints, findings and response most frequent complaints urgency (78%), frequency (71%), suprapubic pain (43%), urge incontinence (21%) dyspareunia (21%). Of 86% did not have history recurrent urinary tract infections, 6 (42%) had endometriosis, including 3...
We determine which urodynamic parameters can best predict postoperative voiding dysfunction following pubovaginal sling surgery.The records of 98 consecutive women who had undergone surgery with allograft fascia lata between July 1998 and 2000 were reviewed. Urodynamic followup data sufficient for evaluation 73 patients. clinical correlated urinary retention, time to return efficient development urgency symptoms.Average was 3.92 days (median 3). Of 21 voided without a detrusor contraction...
Abstract Aims The purpose of this study was to determine whether a percutaneous needle electrode (PNE) technique or surgical first stage lead placement (FSLP) better predicted patient would progress implantation pulse generator (IPG) in older urge incontinent women. Methods Thirty subjects ≥55 years with refractory incontinence who had been selected undergo test stimulation procedure were randomized either PNE FSLP. Thirteen underwent and seventeen FSLP placement. If during the period...
Abstract Aim To evaluate percutaneous placement of electrodes adjacent to the dorsal genital nerve (DGN) and measure effects electrical stimulation on symptoms urge incontinence during 1 week home use. Methods Prospective, multicenter study. Subjects with underwent an electrode using local anesthetic. Test was applied confirm cystometry conducted without application stimulation. A 7‐day testing period connected external pulse generator performed followed by a 3‐day post‐treatment test...
Abstract Aims Pad per day (PPD) usage is a frequently utilized measure of urinary incontinence. The 24‐hour pad weight test (24PWT) reproducible for quantifying incontinence volumes. We investigated whether PPD validly reports the magnitude Methods This was retrospective review patients undergoing stress surgery from July 2002 to 2005. Inclusion criteria were documented 24PWT and patient‐reported usage. Grams urine loss (GPP) provided third Descriptive statistics correlations between all...
In Brief OBJECTIVE: To compare the efficacy of a single-incision mini-sling, placed in "U" position, with tension-free vaginal tape (TVT) treatment stress urinary incontinence. METHODS: Women urodynamic incontinence or without genital prolapse were randomized to receive mini-sling TVT (N=263). Those received two "sham" suprapubic incisions facilitate blinding. The primary outcome was subjective cure (absence any retreatment) as assessed at 1 year. This trial noninferiority study design....
To evaluate whether nitrofurantoin prophylaxis prevents postoperative urinary tract infection (UTI) in patients receiving transurethral catheterization after pelvic reconstructive surgery.In a randomized, double-blind, placebo-controlled trial, participants undergoing surgery were randomized to 100 mg or placebo once daily during if they were: 1) discharged with Foley performing intermittent self-catheterization; 2) hospitalized overnight Foley. Our primary outcome was treatment for...