Wenhao Cheng

ORCID: 0000-0001-6197-8510
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About
Contact & Profiles
Research Areas
  • Infectious Diseases and Mycology
  • Fungal Infections and Studies
  • Mycobacterium research and diagnosis
  • Actinomycetales infections and treatment
  • Pharmacological Effects of Natural Compounds
  • Tuberculosis Research and Epidemiology
  • Parvovirus B19 Infection Studies
  • Antimicrobial Peptides and Activities
  • Mast cells and histamine
  • Immune Response and Inflammation
  • Extracellular vesicles in disease
  • RNA modifications and cancer
  • Ferroptosis and cancer prognosis
  • Histiocytic Disorders and Treatments
  • Reproductive System and Pregnancy
  • Brucella: diagnosis, epidemiology, treatment
  • Cancer-related molecular mechanisms research

Lianyungang Oriental Hospital
2022-2025

Xuzhou Medical College
2021-2024

The First People’s Hospital of Lianyungang
2021-2024

Kangda College of Nanjing Medical University
2024

Nanjing Medical University
2024

This cohort study evaluated the effectiveness and safety of photodynamic therapy (PDT) alone combined with antibiotics for treatment cutaneous Mycobacterium marinum infections.

10.1001/jamadermatol.2025.0645 article EN JAMA Dermatology 2025-04-23

Abstract Background Mycobacterium marinum is a nontuberculous mycobacterium and conditional pathogen to humans, which can be inoculated directly cause chronic skin granulomas. Dermoscopy has been applied other granulomatous diseases, but not M. infection. Aim To explore the dermoscopic features of infection, its correlation with clinical histopathological features. Methods In total, 27 lesions from patients (19 women, 8 men, age range 28–71 years) diagnosed infection were identified by...

10.1093/ced/llac029 article EN Clinical and Experimental Dermatology 2022-10-22

Abstract Nocardia primarily affects immunocompromised individuals, and Infection with is uncommon primary cutaneous nocardiosis caused by percutaneous inoculation even rarer. Primary remains a diagnostic challenge should be considered in the differential diagnosis for any superficial infection that arises patients normal immune function. We report case was diagnosed metagenomic next‐generation sequencing technology.

10.1111/ajd.14187 article EN Australasian Journal of Dermatology 2023-11-20

Recent studies have shown that exosomes are involved in pathogenesis and the treatment of various tumors inflammatory diseases. We examined impacts released from Talaromyces marneffei (T. marneffei)-infected macrophages on human to determine whether they play a role T. infection. Exosomes derived were extracted using commercial kits characterized by transmission electron microscopy western blot. Further, we examine regulate IL-10 TNF-α production activation p42 p44 extracellular...

10.22541/au.170663553.34717745/v1 preprint EN Authorea (Authorea) 2024-01-30

The 47-kDa membrane lipoprotein (Tp47) is the most representative protein of Treponema pallidum (T. pallidum). Dendritic cells (DCs) are potent professional antigen-presenting (APCs) that connect innate and acquired immunity. regulatory role Tp47 on DCs remains unclear.To evaluate effects DC maturation migration, research changes main chemokine C-C receptor type 7 (CCR7) involved in migration.A transwell assay was applied to assess migration DCs. Cytokines (interleukin (IL)-6, IL-10, IL-12,...

10.17219/acem/154857 article EN cc-by Advances in Clinical and Experimental Medicine 2022-11-04

Atopic dermatitis (AD) is a common chronic, recurrent, and non-infectious inflammatory skin disease. Dupilumab human monoclonal antibody with clinical efficacy in severe AD has good safety profile.

10.1159/000539704 article EN cc-by-nc Case Reports in Dermatology 2024-07-01

Ferroptosis is a type of regulated necrosis induced by accumulation free iron and toxic lipid peroxides. However, it unknown that whether ferroptosis, recently identified form lytic cell death, was involved in pathogenicity Mycobacterium marinum (M.marinum). Therefore, to explore the relationship between ferroptosis multiplication M.marinum investigate autophagy regulates during infection human macrophages. Macrophages were infected with for different times. First, we found reduced levels...

10.2139/ssrn.4352898 article EN 2023-01-01
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